Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Huda Atiya"'
Publikováno v:
Gynecologic Oncology. 166:S62
Publikováno v:
Journal of visualized experiments : JoVE. (169)
Ovarian cancer is characterized by early, diffuse metastasis with 70% of women having metastatic disease at the time of diagnosis. While elegant transgenic mouse models of ovarian cancer exist, these mice are expensive and take a long time to develop
Autor:
Steffi Oesterrich, Tracy Tabib, Robert Lafyatis, Irina Abecassis, Caleb Lampenfeld, Huda Atiya, Sheryl Kunning, Anthony R. Cillo, Cornelius H. L. Kürten, Robert L. Ferris, Seungwon Kim, Sayali Onkar, Ryan J. Soose, Ayana T. Ruffin, Zengbiao Qi, Tullia C. Bruno, Lan G. Coffman, Dario A. A. Vignali, Angen Liu, Umamaheswar Duvvuri
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
Current immunotherapy paradigms aim to reinvigorate CD8+ T cells, but the contribution of humoral immunity to antitumor immunity remains understudied. Here, we demonstrate that in head and neck squamous cell carcinoma (HNSCC) caused by human papillom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1545d2f469a1420d1f490a1d372b94de
https://www.ncbi.nlm.nih.gov/pubmed/34099645
https://www.ncbi.nlm.nih.gov/pubmed/34099645
Autor:
Hui Shen, Thomas R. Pisanic, Kelly K. Foy, Yeh Wang, Huihui Fan, Ie Ming Shih, Chelsea Chandler, Huda Atiya, Lan G. Coffman, Jeff Wang, Leonard Frisbie
SummaryOvarian cancer develops early intra-peritoneal metastasis establishing a supportive tumor microenvironment (TME) through reprogramming normal mesenchymal stem cells into carcinoma-associated mesenchymal stem cells (CA-MSCs). CA-MSCs are the st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c3996f8b0787735958d0e6451d2e97d
Publikováno v:
Advances in experimental medicine and biology. 1234
The interactions between tumor cells and the non-malignant stromal and immune cells that make up the tumor microenvironment (TME) are critical to the pathophysiology of cancer. Mesenchymal stem cells (MSCs) are multipotent stromal stem cells found wi
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9783030371838
The interactions between tumor cells and the non-malignant stromal and immune cells that make up the tumor microenvironment (TME) are critical to the pathophysiology of cancer. Mesenchymal stem cells (MSCs) are multipotent stromal stem cells found wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::145b2be0d2e658190cb01c9a9723fcde
https://doi.org/10.1007/978-3-030-37184-5_3
https://doi.org/10.1007/978-3-030-37184-5_3
Publikováno v:
Journal of Clinical Oncology. 39:5561-5561
5561 Background: Endometriosis-associated carcinomas (EACs) such as ovarian clear cell cancer (OCCC) are rare, aggressive, chemo-resistant malignancies. While endometriosis is a known chronic inflammatory condition, the molecular mechanisms for the m
Publikováno v:
Cancer Research. 80:1446-1446
Introduction: Ovarian cancer is the deadliest gynecologic malignancy in the USA, and many patients incur diffuse metastases before diagnosis. In order to improve prognoses and reveal novel therapeutics, we must understand the mechanisms of ovarian tu
Publikováno v:
Web of Science
e18072 Background: Carcinoma-associated mesenchymal stem cells (CA-MSCs) are mesenchymal stem cells (MSCs) within the tumor microenvironment (TME). We demonstrated that CA-MSCs promote ovarian cancer chemotherapy resistance through paracrine signalin
Autor:
Huda Atiya, Huihui Fan, Kelly K. Foy, Thomas R. Pisanic, Ronald J. Buckanovich, Leonard Frisbie, Alison A. Chomiak, Ie Ming Shih, Scott B. Rothbart, Chelsea Chandler, Tza-Huei Wang, Rochelle L. Tiedemann, Hui Shen, Yeh Wang, Lan G. Coffman
Publikováno v:
Cell reports
SUMMARY A role for cancer cell epithelial-to-mesenchymal transition (EMT) in cancer is well established. Here, we show that, in addition to cancer cell EMT, ovarian cancer cell metastasis relies on an epigenomic mesenchymal-to-epithelial transition (