Zobrazeno 1 - 10
of 197
pro vyhledávání: '"Hubertus Jarry"'
Autor:
Philipp Kauffmann, Anna Rau, Dana Seidlová-Wuttke, Hubertus Jarry, Boris Schminke, Swantje Matthes, Karl Günter Wiese
Publikováno v:
Bone Reports, Vol 13, Iss , Pp 100300- (2020)
Introduction: The aim of this study was to investigate the effect of dihydrotestosterone (DHT), 17-β-estrogen (E2), genistein (GEN) and equol (EQ) on bone remodeling and bone morphology during healing of osteoporotic male rat tibiae. Materials and m
Externí odkaz:
https://doaj.org/article/0973bc1eac744acbadb8cb2b5cbaa2b0
Autor:
Tobias J. Legler, Susanne Papert, Hubertus Jarry, Holger M. Reichardt, Joachim Riggert, Holger Budde
Publikováno v:
Vox Sanguinis. 113:803-810
BACKGROUND AND OBJECTIVE Extracorporeal photopheresis (ECP) is an important immune tolerance inducing therapy for graft-versus-host disease (GvHD). However, a sufficient number of ECP cycles cannot be performed in patients with severe GvHD and contra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f472e035f8ee37bebbefc58e163f70c
https://doi.org/10.1111/vox.12723
https://doi.org/10.1111/vox.12723
Autor:
Lars Fester, Christiana Ossig, Hubertus Jarry, Lepu Zhou, Gabriele M. Rune, Günter Vollmer, Manuela I. Bader, Jan Labitzke, Corinna Bläute
Publikováno v:
Journal of Neurochemistry. 140:126-139
Locally synthesized estradiol plays an important role in synaptic plasticity in the hippocampus. We have previously shown that in hippocampal neurons, activity of the enzyme aromatase, which converts testosterone into estradiol, is reduced via Ca2+ -
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bedbb0b196a5c348fbe532c668ea9c87
https://doi.org/10.1111/jnc.13889
https://doi.org/10.1111/jnc.13889
Autor:
Felix, Bremmer, Hubertus, Jarry, Valerie, Unterkircher, Silke, Kaulfuss, Peter, Burfeind, Heinz-Joachim, Radzun, Philipp, Ströbel, Paul, Thelen
Publikováno v:
Oncotarget
Novel treatments for castration-resistant prostate cancer (CRPC) such as abiraterone acetate (AA) or enzalutamide effectively target the androgen pathway to arrest aberrant signalling and cell proliferation. Testosterone is able to inhibit tumour cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5b990d6b0eb7f099dee5366877855e01
https://pubmed.ncbi.nlm.nih.gov/29682196
https://pubmed.ncbi.nlm.nih.gov/29682196
Autor:
Maike Hassenpflug, Ba Tiep Nguyen, Laura C Zelarayan, Martin Bergmann, Gerd Hasenfuss, Georgios Kararigas, Hugo Sanchez-Ruderisch, Vera Regitz-Zagrosek, Karl Toischer, Hubertus Jarry
Publikováno v:
Endocrinology. 155:2667-2676
Estrogen regulates several biological processes in health and disease. Specifically, estrogen exerts antihypertrophic effects in the diseased heart. However, its role in the healthy heart remains elusive. Our initial aim was to identify the effects o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44df85bb432c0ec6cddae271b94384d9
https://doi.org/10.1210/en.2013-2180
https://doi.org/10.1210/en.2013-2180
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 139:245-251
In 1996, the molecular biology of E2 had to be reevaluated: in an effort to identify novel nuclear receptors or unknown isoforms of existing receptors Kuiper and colleague described the expression of a novel subtype of the estrogen receptor (ER) in r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55a9733446866b46c13ad22bd80e46e1
https://doi.org/10.1016/j.jsbmb.2013.03.003
https://doi.org/10.1016/j.jsbmb.2013.03.003
Autor:
Tobias Schmutterer, Gabriele M. Rune, Ricardo Vierk, Janine Prange-Kiel, Philipp Imholz, Lars Fester, Hubertus Jarry, Nicola Brandt, Lepu Zhou
Publikováno v:
Progress in Histochemistry and Cytochemistry. 48:49-64
Estradiol synthesis in the ovaries is regulated via feedback mechanisms mediated by gonadotrophin-releasing hormone (GnRH) and gonadotrophins, secreted by the hypothalamus and the pituitary, respectively. Estradiol synthesis also takes place in the h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac6fb345886c30147749a99cf775e7fe
https://doi.org/10.1016/j.proghi.2013.07.002
https://doi.org/10.1016/j.proghi.2013.07.002
Publikováno v:
Toxicology. 304:69-75
Equol (EQ), a potent biologically active metabolite of the soy isoflavone daidzein, interacts with estrogen receptors (ERs), however, as suggested recently, EQ may also exert anti-androgenic actions in androgen regulated tissues like prostate and sem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab9fd21e16d6dc36d5df366bded49eea
https://doi.org/10.1016/j.tox.2012.11.017
https://doi.org/10.1016/j.tox.2012.11.017
Autor:
Karl Toischer, Vera Regitz-Zagrosek, Georgios Kararigas, Hubertus Jarry, Gerd Hasenfuss, Laura C Zelarayan
Publikováno v:
Circulation Research. 119
The role of β-catenin and the actions of 17β-estradiol (E2) in cardiovascular (patho)physiology remain unclear. In the diseased heart, E2 is expected to be cardioprotective. However, in the absence of prior disease, complications in pregnancy or tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::072615bd9c4ae076db05bfa85553ba97
https://doi.org/10.1161/res.119.suppl_1.400
https://doi.org/10.1161/res.119.suppl_1.400
Autor:
Lepu Zhou, Julia Böhm, Janine Prange-Kiel, Gabriele M. Rune, Lars Fester, Breda v. Blittersdorf, Hubertus Jarry, Michael Schumacher
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 131:24-29
Hippocampal neurons are capable of synthesizing estradiol de novo. Estradiol synthesis can be suppressed by aromatase inhibitors and by knock-down of steroid acute regulatory protein (StAR), whereas elevated levels of substrates of steroidogenesis en
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3284229be86c17d96ecc5f827984330e
https://doi.org/10.1016/j.jsbmb.2011.11.010
https://doi.org/10.1016/j.jsbmb.2011.11.010