Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Hubertine M E Willems"'
Autor:
Junyan Liu, Hubertine M E Willems, Emily A Sansevere, Stefanie Allert, Katherine S Barker, David J Lowes, Andrew C Dixson, Zhenbo Xu, Jian Miao, Christian DeJarnette, Helene Tournu, Glen E Palmer, Jonathan P Richardson, Francisco N Barrera, Bernhard Hube, Julian R Naglik, Brian M Peters
Publikováno v:
PLoS Pathogens, Vol 17, Iss 9, p e1009884 (2021)
Vulvovaginal candidiasis (VVC), caused primarily by the human fungal pathogen Candida albicans, results in significant quality-of-life issues for women worldwide. Candidalysin, a toxin derived from a polypeptide (Ece1p) encoded by the ECE1 gene, play
Externí odkaz:
https://doaj.org/article/b3e2ce06c5484147bdbc2ffbdee60a64
Autor:
Emily Rayens, Whitney Rabacal, Hubertine M E Willems, Gabrielle M Kirton, James P Barber, Jarrod J Mousa, Brandi N Celia-Sanchez, Michelle Momany, Karen A Norris
Publikováno v:
PNAS Nexus. 1
Invasive fungal infections cause over 1.5 million deaths worldwide. Despite increases in fungal infections as well as the numbers of individuals at risk, there are no clinically approved fungal vaccines. We produced a “pan-fungal” peptide, NXT-2,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9e5cfcc53889bb05eb05d5379f44d821
https://doi.org/10.1093/pnasnexus/pgac248
https://doi.org/10.1093/pnasnexus/pgac248
Autor:
Hubertine M. E. Willems, Andrew C. Dixson, Glen E. Palmer, Junyan Liu, Stefanie Allert, Francisco N. Barrera, Brian M. Peters, Helene Tournu, Jonathan P. Richardson, Jian Miao, Christian DeJarnette, Bernhard Hube, David J. Lowes, Katherine S. Barker, Zhenbo Xu, Julian R. Naglik, Emily A. Sansevere
Publikováno v:
PLoS Pathogens, Vol 17, Iss 9, p e1009884 (2021)
PLoS Pathogens
PLoS Pathogens
Vulvovaginal candidiasis (VVC), caused primarily by the human fungal pathogen Candida albicans, results in significant quality-of-life issues for women worldwide. Candidalysin, a toxin derived from a polypeptide (Ece1p) encoded by the ECE1 gene, play
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5540c6efd61dc51cb2045f29d6cd489e
https://doaj.org/article/b3e2ce06c5484147bdbc2ffbdee60a64
https://doaj.org/article/b3e2ce06c5484147bdbc2ffbdee60a64
Publikováno v:
Infect Immun
While human vaginal pH in childbearing aged women is conclusively acidic, the mouse vaginal pH is reported as being near neutral. However, this information appears to be somewhat anecdotal with respect to vulvovaginal candidiasis as such claims in th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a25aa216037b1534806fb1b631b7600
https://doi.org/10.1128/iai.00550-20
https://doi.org/10.1128/iai.00550-20
Publikováno v:
Journal of Fungi
Journal of Fungi, Vol 6, Iss 1, p 27 (2020)
Journal of Fungi, Vol 6, Iss 1, p 27 (2020)
Candida albicans, along with other closely related Candida species, are the primary causative agents of vulvovaginal candidiasis (VVC)—a multifactorial infectious disease of the lower female reproductive tract resulting in pathologic inflammation.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6870c1cac52a3ec7ed2832263a5388cb
http://europepmc.org/articles/PMC7151053
http://europepmc.org/articles/PMC7151053
Autor:
Hubertine M. E. Willems, Jenneke Klein-Nulend, Ruud J. W. Schoemaker, Astrid D. Bakker, Ellen G. H. M. van den Heuvel
Publikováno v:
Current Osteoporosis Reports
Willems, H M E, van den Heuvel, E G H M, Schoemaker, R J W, Klein-Nulend, J & Bakker, A D 2017, ' Diet and exercise : a match made in bone ', Current Osteoporosis Reports, vol. 15, no. 6, pp. 555-563 . https://doi.org/10.1007/s11914-017-0406-8
Willems, H M E, van den Heuvel, E G H M, Schoemaker, R J W, Klein-Nulend, J & Bakker, A D 2017, ' Diet and exercise : a match made in bone ', Current Osteoporosis Reports, vol. 15, no. 6, pp. 555-563 . https://doi.org/10.1007/s11914-017-0406-8
Purpose of Review: Multiple dietary components have the potential to positively affect bone mineral density in early life and reduce loss of bone mass with aging. In addition, regular weight-bearing physical activity has a strong positive effect on b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::763cc9fb1d63de848764fa56083e3e99
https://doi.org/10.1007/s11914-017-0406-8
https://doi.org/10.1007/s11914-017-0406-8
Autor:
Hubertine M. E. Willems, Nina Scheres, Carolien S. Bode, Bastiaan P. Krom, Devon L. Allison, Mark E. Shirtliff
Publikováno v:
Infection and Immunity, 87(11):e00137-19. American Society for Microbiology
Allison, D L, Scheres, N, Willems, H M E, Bode, C S, Krom, B P & Shirtliff, M E 2019, ' The Host Immune System Facilitates Disseminated Staphylococcus aureus Disease Due to Phagocytic Attraction to Candida albicans during Coinfection : a Case of Bait and Switch ', Infection and Immunity, vol. 87, no. 11, e00137-19 . https://doi.org/10.1128/IAI.00137-19
Allison, D L, Scheres, N, Willems, H M E, Bode, C S, Krom, B P & Shirtliff, M E 2019, ' The Host Immune System Facilitates Disseminated Staphylococcus aureus Disease Due to Phagocytic Attraction to Candida albicans during Coinfection : a Case of Bait and Switch ', Infection and Immunity, vol. 87, no. 11, e00137-19 . https://doi.org/10.1128/IAI.00137-19
Invasive Staphylococcus aureus infections account for 15 to 50% of fatal bloodstream infections annually. These disseminated infections often arise without a defined portal of entry into the host but cause high rates of mortality. The fungus Candida
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c88deeba38c69442543ccb64ef3e01ea
https://doi.org/10.1128/iai.00137-19
https://doi.org/10.1128/iai.00137-19
Autor:
Felix E. Y. Aggor, Sarah L. Gaffen, Srinivas Bishu, Bianca M. Coleman, Vincent M. Bruno, Anna H Huppler, Brian M. Peters, Ellyse M Cipolla, Akash H. Verma, Katherine S. Barker, Hubertine M. E. Willems
Publikováno v:
J Infect Dis
Candida albicans, a ubiquitous commensal fungus that colonizes human mucosal tissues and skin, can become pathogenic, clinically manifesting most commonly as oropharyngeal candidiasis and vulvovaginal candidiasis (VVC). Studies in mice and humans con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad1b591e49966fa2738b017722d42d0a
https://pubmed.ncbi.nlm.nih.gov/31805183
https://pubmed.ncbi.nlm.nih.gov/31805183
Autor:
Brian M. Peters, Jabez P Fortwendel, Hubertine M. E. Willems, Molly E Coltrane, Jeremy S. Stultz
Publikováno v:
Antimicrobial agents and chemotherapy. 63(11)
Receipt of parenteral nutrition (PN) remains an independent risk factor for developing catheter-related bloodstream infections (CR-BSI) caused by fungi, including by the polymorphic fungus Candida albicans, which is notoriously adept at forming drug-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf1f0c0c339c52250d0ec84ea0494101
https://pubmed.ncbi.nlm.nih.gov/31405860
https://pubmed.ncbi.nlm.nih.gov/31405860
Publikováno v:
Current Oral Health Reports. 3:36-44
Microbes rarely exist as single species planktonic forms as they have been commonly studied in the laboratory. Instead, the vast majority exists as part of complex polymicrobial biofilm communities attached to host and environmental surfaces. The ora
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55df69601dc43148a11a888434fbb3f8
https://doi.org/10.1007/s40496-016-0078-y
https://doi.org/10.1007/s40496-016-0078-y