Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Hubert Wolfger"'
Publikováno v:
The Journal of Membrane Biology
Rockwell, Nathan C.; Wolfger, Hubert; Kuchler, Karl; & Thorner, Jeremy. (2009). ABC Transporter Pdr10 Regulates the Membrane Microenvironment of Pdr12 in Saccharomyces cerevisiae. Journal of Membrane Biology, 229(1), pp 27-52. doi: 10.1007/s00232-009-9173-5. Retrieved from: http://www.escholarship.org/uc/item/3tm2b87j
Rockwell, Nathan C.; Wolfger, Hubert; Kuchler, Karl; & Thorner, Jeremy. (2009). ABC Transporter Pdr10 Regulates the Membrane Microenvironment of Pdr12 in Saccharomyces cerevisiae. Journal of Membrane Biology, 229(1), pp 27-52. doi: 10.1007/s00232-009-9173-5. Retrieved from: http://www.escholarship.org/uc/item/3tm2b87j
The eukaryotic plasma membrane exhibits both asymmetric distribution of lipids between the inner and the outer leaflet and lateral segregation of membrane components within the plane of the bilayer. In budding yeast (Saccharomyces cerevisiae), mainte
Publikováno v:
Annals of Tropical Medicine & Parasitology. 98:643-649
Data indicate a potential role for the Pdr5p P-glycoprotein ATP-binding-cassette (ABC) transporter in mediating chloroquine sensitivity in S. cervisae. This is consistent with the hypothesis that such a transporter plays a role in mediating quinoline
Autor:
Yasmine M. Mamnun, Thomas Eggmann, Karl Kuchler, Hubert Wolfger, Christoph Schüller, Enrico Martinoia, Markus Klein
Publikováno v:
FEBS Letters. 520:63-67
Vacuolar sequestration or cellular extrusion of glutathione-conjugated xenobiotics and catabolites by ATP-binding cassette (ABC) transporters is an important detoxification mechanism operating in many species. In this study, we show that the yeast AB
Publikováno v:
FEBS Letters. 418:269-274
The yeast transcription factors Pdr1 and Pdr3 control pleiotropic drug resistance (PDR) development, since they regulate expression of ATP-binding cassette (ABC) drug efflux pumps through binding to cis-acting sites known as PDREs ( PD R r esponsive
Autor:
Nathan C. Rockwell, Karl Kuchler, Christoph Schüller, Jeremy Thorner, Yasmine M. Mamnun, Hubert Wolfger
Publikováno v:
Molecular biology of the cell. 18(12)
The Saccharomyces cerevisiae zinc cluster transcription factors Pdr1 and Pdr3 mediate general drug resistance to many cytotoxic substances also known as pleiotropic drug resistance (PDR). The regulatory mechanisms that activate Pdr1 and Pdr3 in respo
Publikováno v:
The Journal of biological chemistry. 279(12)
ATP-binding cassette (ABC) transporters play important roles in drug efflux, but some may also function in cellular detoxification. The Pdr15p ABC protein is the closest homologue of the multidrug efflux transporter Pdr5p, which mediates pleiotropic
Autor:
Hubert Wolfger, Bettina E. Bauer, Peter W. Piper, Christa Gregori, Karl Kuchler, Christoph Schüller, Yasmine M. Mamnun, Kostas Hatzixanthis, Mehdi Mollapour, Angelika Kren
The Saccharomyces cerevisiae ATP-binding cassette (ABC) transporter Pdr12p effluxes weak acids such as sorbate and benzoate, thus mediating stress adaptation. In this study, we identify a novel transcription factor, War1p, as the regulator of this st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d94ceac9228b907d25e654570e805cd
https://europepmc.org/articles/PMC151711/
https://europepmc.org/articles/PMC151711/
Publikováno v:
Research in microbiology. 152(3-4)
A number of prominent genetic diseases are caused by mutations in genes encoding ATP-binding cassette (ABC) proteins (Ambudkar, Gottesmann, 1998). Moreover, several mammalian ABC proteins such as P-glycoprotein (P-gp) (Gottesman et al., 1995) and mul
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Biomembranes. (2):217-236
Saccharomyces cerevisiae was the first eukaryotic organism whose complete genome sequence has been determined, uncovering the existence of numerous genes encoding proteins of the ATP-binding cassette (ABC) family. Fungal ABC proteins are implicated i