Zobrazeno 1 - 10
of 82
pro vyhledávání: '"Hubert Th. Wolterbeek"'
Publikováno v:
EJNMMI Radiopharmacy and Chemistry, Vol 4, Iss 1, Pp 1-12 (2019)
Abstract Background In this work, a lutetium-177 (177Lu) production method based on the separation of nuclear isomers, 177mLu & 177Lu, is reported. The 177mLu-177Lu separation is performed by combining the use of DOTA & DOTA-labelled peptide (DOTATAT
Externí odkaz:
https://doaj.org/article/9ac50a2aa75947e18da93eebc2dd0297
Autor:
Chao Ma, Pablo Serra Crespo, Antonia G. Denkova, Hubert Th. Wolterbeek, Alexandros Vasileiadis
Publikováno v:
Applied Surface Science, 572
The potential of the metal–organic framework UiO-66 and its functionalized derivatives for their utilization in the 99Mo/99mTc generator was assessed. Molybdenum adsorption experiments, structure characterization, molecular simulations and column e
Publikováno v:
Applied Radiation and Isotopes, 164
A solid phase extraction based 177mLu-177Lu separation method has been investigated for its feasibility to be used in the radionuclide generator. The use of 2,2′,2”-(10-(2,6-dioxotetrahydro-2H-pyran-3-yl)-1,4,7,10-tetraazacyclododecane-1,4,7-triy
Publikováno v:
Applied Radiation and Isotopes, 166
In order to determine the potential of 177mLu/177Lu radionuclide generator in 177Lu production it is important to establish the technical needs that can lead to a clinically acceptable 177Lu product quality. In this work, a model that includes all th
Autor:
Antonia G. Denkova, Hubert Th. Wolterbeek, Matthew B. E. Griffiths, Josette L. T. M. Moret, Baukje E. Terpstra, J. Ruud van Ommen, Seán T. Barry, Jeannine E. B. M. Frijns
Publikováno v:
Journal of Vacuum Science and Technology. Part A: International Journal Devoted to Vacuum, Surfaces, and Films, 38(2)
Atomic layer deposition (ALD) is a versatile gas phase coating technique that allows coating of complex structured materials, as well as high-surface area materials such as nanoparticles. In this work, ALD is used to deposit a lutetium oxide layer on
Autor:
Hubert Th. Wolterbeek, J.R. van Ommen, O. van Batenburg, T.A. Hardens, J.L.T.M. Moret, Antonia G. Denkova
Publikováno v:
Applied Radiation and Isotopes, 160
Cu is an important trace metal which plays a role in many biological processes. The radioisotope 64Cu is often used to study such processes. Furthermore, 64Cu finds applications in cancer diagnostics as well as therapy. For all of these applications
Autor:
Jan Willem J. van Dorp, Pablo Serra-Crespo, Peter Bode, Dravin S. Mahes, Hubert Th. Wolterbeek, Antonia G. Denkova
Publikováno v:
Applied Radiation and Isotopes. 140:138-145
The neutron irradiation of molybdenum hexacarbonyl has been systematically studied to identify possible improvements for the production of molybdenum-99. After irradiation, the targets were dissolved in dichloromethane, and Szilard-Chalmers liquid-li
Publikováno v:
Radiation Oncology, Vol 13, Iss 1, Pp 1-11 (2018)
Radiation Oncology (London, England)
Radiation Oncology, 13(1)
Radiation Oncology (London, England)
Radiation Oncology, 13(1)
Background: While alpha microdosimetry dates back a couple of decades, the effects of localized energy deposition of alpha particles are often still unclear since few comparative studies have been performed. Most modern alpha microdosimetry studies r
Autor:
Johan A. Slotman, Antonia G. Denkova, Hubert Th. Wolterbeek, Adrie J. J. Bos, J.J.M. Kouwenberg, Adriaan B. Houtsmuller, Gert-Jan Kremers
Publikováno v:
Journal of Microscopy. 270:326-334
Structured illumination microscopy (SIM) for the imaging of alpha particle tracks in fluorescent nuclear track detectors (FNTD) was evaluated and compared to confocal laser scanning microscopy (CLSM). FNTDs were irradiated with an external alpha sour
Autor:
Frank Bruchertseifer, Antonia G. Denkova, Danny Lathouwers, L. Thijssen, Alfred Morgenstern, R.M. de Kruijff, Hubert Th. Wolterbeek, K. Drost
Publikováno v:
Applied Radiation and Isotopes. 128:183-189
Alpha-emitting radionuclides like actinium-225 (225Ac) are ideal candidates for the treatment of small metastasised tumours, where the long half-life of 225Ac enables it to also reach less accessible tumours. The main challenge lies in retaining the