Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Hubert Stangl"'
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0139726 (2015)
Excessive synovial osteoclastogenesis is a hallmark of rheumatoid arthritis (RA). Concomitantly, local synovial changes comprise neuronal components of the peripheral sympathetic nervous system. Here, we wanted to analyze if collagen-induced arthriti
Externí odkaz:
https://doaj.org/article/b36cade528674aaa84824f0c307ce78f
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
In experimental arthritis, glucocorticoid secretion is inadequate relative to inflammation. We hypothesized that IL-1 is a key factor for inadequate glucocorticoid secretion in arthritic rats. Collagen type II—induced arthritis (CIA) in DA rats was
OBJECTIVE Patients with chronic inflammatory autoimmune diseases benefit from a broad spectrum of immunosuppressive and antiproliferative medication available today. However, nearly all of these therapeutic compounds have unwanted toxic side effects.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b41341444c95d5fe7f973d35d6da376
https://www.ncbi.nlm.nih.gov/pubmed/31509354
https://www.ncbi.nlm.nih.gov/pubmed/31509354
Autor:
Andreas Sellmer, Sigurd Elz, Emerich Eichhorn, Michel Leonhardt, Oliver H. Krämer, Rainer H. Straub, Elisabeth Grünstein, Hubert Stangl, Herwig Pongratz, Siavosh Mahboobi, Birgit Striegl, Mandy Beyer, Stefan Dove, Zsuzsa Jenei-Lanzl
Publikováno v:
Journal of Medicinal Chemistry. 61:3454-3477
Epigenetic modifiers of the histone deacetylase (HDAC) family contribute to autoimmunity, cancer, HIV infection, inflammation, and neurodegeneration. Hence, histone deacetylase inhibitors (HDACi), which alter protein acetylation, gene expression patt
Autor:
Zsuzsa Jenei-Lanzl, Mieczyslaw Gajda, Rainer H. Straub, Hubert Stangl, Gisela Segond von Banchet, Hans-Georg Schaible, Matthias Ebbinghaus
Publikováno v:
Neuroimmunomodulation. 25:225-237
Objectives: The appearance of endogenous tyrosine hydroxylase-positive cells (TH+ cells) in collagen-induced arthritis was associated with an anti-inflammatory effect. Here we investigated putative anti-inflammatory and antinociceptive effects of the
Publikováno v:
Physiological Reports
Previously, we reported that cervical vagal nerve stimulation (VNS) increases blood glucose levels and inhibits insulin secretion in anesthetized rats through afferent signaling. Since afferent signaling is also thought to mediate the therapeutic eff
Publikováno v:
Brain, Behavior, and Immunity. 54:201-210
Objectives In collagen type II-induced arthritis (CIA), early activation of the sympathetic nervous system (SNS) is proinflammatory. Here, we wanted to find new target organs contributing to proinflammatory SNS effects. In addition, we wanted to clar
Publikováno v:
Brain, Behavior, and Immunity. 81:50
Autor:
Hubert Stangl, Harald M. Stauss
Publikováno v:
The FASEB Journal. 32
Autor:
Roland Kontermann, John R. Bethea, Maëlle Duffey, Marcel Proske, Nathalie Peters, George F. Martinez, Rainer H. Straub, Hubert Stangl, Alexandra Kraske, Roman Fischer, Klaus Pfizenmaier
Publikováno v:
Arthritisrheumatology (Hoboken, N.J.). 70(5)
Objective. Treg cells modulate immune responses and can suppress the development of autoimmune diseases. Tumor necrosis factor receptor II (TNFRII) has been recognized as a key receptor on these cells that facilitates expansion and stabilization of C