Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Hubert Hon"'
Publikováno v:
FASEB BioAdvances, Vol 6, Iss 10, Pp 401-405 (2024)
Abstract The prolonged war in Ukraine is having a strong impact on all sectors of the Ukrainian society, including biomedical research. Although the material and psychological conditions are challenging, the country and its researchers are courageous
Externí odkaz:
https://doaj.org/article/f889dd5e6bf6482c85793b5cbd49b66f
Autor:
Amiee Dowdell, Mark Marsland, Sam Faulkner, Craig Gedye, James Lynam, Cassandra P. Griffin, Joanne Marsland, Chen Chen Jiang, Hubert Hondermarck
Publikováno v:
FASEB BioAdvances, Vol 5, Iss 5, Pp 211-220 (2023)
Abstract Glioblastoma (GBM) is the most frequent and deadly primary brain tumor in adults. Temozolomide (TMZ) is the standard systemic therapy in GBM but has limited and restricted efficacy. Better treatments are urgently needed. The role of endoplas
Externí odkaz:
https://doaj.org/article/dae1375758924a559c52ffbca810fcf9
Autor:
Marie Winter, Amina Nait Eldjoudi, Catherine Guette, Hubert Hondermarck, Roland P. Bourette, Quentin Fovez, William Laine, Bart Ghesquiere, Eric Adriaenssens, Jérôme Kluza, Xuefen Le Bourhis
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 46, Iss , Pp 100949- (2023)
Triple negative breast cancer (TNBC) is an aggressive malignancy for which chemotherapy remains the standard treatment. However, between 3 and 5 years after chemotherapy, about half patients will relapse and it is essential to identify vulnerabilitie
Externí odkaz:
https://doaj.org/article/e150c68e372041aeaf4d518f13976bcb
Autor:
Dong Li, Li Na Hu, Si Min Zheng, Ting La, Li Yuan Wei, Xiao Jun Zhang, Zhen Hua Zhang, Jun Xing, Li Wang, Ruo Qi Li, Qin Zhu, Rick F. Thorne, Yu Chen Feng, Hubert Hondermarck, Xu Dong Zhang, Li Li, Jin Nan Gao
Publikováno v:
FASEB BioAdvances, Vol 4, Iss 6, Pp 391-401 (2022)
Abstract Active crosstalk between the nervous system and breast cancer cells has been experimentally demonstrated in vitro and in animal models. However, low frequencies of peripheral nerve presence in human breast cancers reported in previous studie
Externí odkaz:
https://doaj.org/article/282bc27f9403481e905ec2be6fcf3d2e
Autor:
Hubert Hon, Heino Stass, Rudo Mathivha, Jeffrey Lipman, A.G.S. Gous, Mary Pinder, Lia Verhoef, J. Scribante, Shephelia Tshukutsoane
Publikováno v:
International Journal of Antimicrobial Agents. 26:50-55
This study aimed to investigate whether fluid shifts alter ciprofloxacin pharmacokinetics in critically ill patients over time. Patients >= 18 years, with normal renal function, requiring intensive care treatment and parenteral antibiotics were enrol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::865ce6ed7fd554fac00944b33edaa889
https://doi.org/10.1016/j.ijantimicag.2005.04.005
https://doi.org/10.1016/j.ijantimicag.2005.04.005
Publikováno v:
FASEB BioAdvances, Vol 4, Iss 1, Pp 22-28 (2022)
Abstract Nerve dependence in regeneration has been established more than 200 years ago but the mechanisms by which nerves are necessary to regeneration remain to be fully elucidated. Aside from their direct impact in stimulating cellular growth, nerv
Externí odkaz:
https://doaj.org/article/a34b039405304f8084b3528cb2a92753
Publikováno v:
FASEB BioAdvances, Vol 3, Iss 11, Pp 944-952 (2021)
Abstract Although the role of nerves in stimulating cellular growth and dissemination has long been described in tissue regeneration studies, until recently a similar trophic role of nerves in disease was not well recognized. However, recent studies
Externí odkaz:
https://doaj.org/article/210835dfc91d44de8e5fda9754e2c511
Autor:
Brayden March, Kathleen Rebecca Lockhart, Sam Faulkner, Markus Smolny, Robert Rush, Hubert Hondermarck
Publikováno v:
FASEB BioAdvances, Vol 3, Iss 11, Pp 888-896 (2021)
Abstract Non‐invasive procedures are needed for prostate cancer management, and urine represents a potential source of new biomarkers with translational value. Recent evidence has shown that the growth of new nerves in the tumor microenvironment is
Externí odkaz:
https://doaj.org/article/882a5c98a64b404a84e760134e9732fc
Autor:
Aysha Ferdoushi, Nathan Griffin, Mark Marsland, Xiaoyue Xu, Sam Faulkner, Fangfang Gao, Hui Liu, Simon J. King, James W. Denham, Dirk F. van Helden, Phillip Jobling, Chen Chen Jiang, Hubert Hondermarck
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Pancreatic cancer is a highly aggressive malignancy characterized by poor survival, recurrence after surgery and resistance to therapy. Nerves infiltrate the microenvironment of pancreatic cancers and contribute to tumor progression, however
Externí odkaz:
https://doaj.org/article/57ebd719b81a48ceb0a7183729c7fd08
Autor:
Sam Faulkner, Nathan Griffin, Christopher W. Rowe, Phillip Jobling, Janine M. Lombard, Sonia M. Oliveira, Marjorie M. Walker, Hubert Hondermarck
Publikováno v:
FASEB BioAdvances, Vol 2, Iss 7, Pp 398-408 (2020)
Abstract Nerve growth factor (NGF) and its receptors are increasingly implicated in cancer progression, but their expression in cervical cancer is unclear. The objective of this study was to define the protein expression of NGF, its precursor (proNGF
Externí odkaz:
https://doaj.org/article/c993e07b2b364f0ea4cb27aaf9d18bbb