Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Hubert Heuer"'
Autor:
Werner Kramer, Siegfried Stengelin, Karl-Heinz Baringhaus, Alfons Enhsen, Hubert Heuer, Wolfgang Becker, Daniel Corsiero, Frank Girbig, Rüdiger Noll, Claudia Weyland
Publikováno v:
Journal of Lipid Research, Vol 40, Iss 9, Pp 1604-1617 (1999)
The substrate specificity of the ileal and the hepatic Na+/bile acid cotransporters was determined using brush border membrane vesicles and CHO cell lines permanently expressing the Na+/bile acid cotransporters from rabbit ileum or rabbit liver. The
Externí odkaz:
https://doaj.org/article/0bd38c9e399a469881c5111bbb621130
Autor:
Oliver Plettenburg, Harm Brummerhop, Andreas W. Herling, Werner Kramer, Martin Bickel, Ulrich Werner, Wendelin Frick, Hubert Heuer, Heiner Glombik, Stefan Theis
Publikováno v:
Arzneimittelforschung. 58:574-580
AVE2268, a substituted glycopyranoside, is an orally active and selective inhibitor of sodium-dependent glucose transporter 2 (SGLT2; IC50 = 13 nmol/L). Investigation of the pharmacological profile of AVE2268 on urinary glucose excretion (UGE) and bl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52c880f86e4382ce32f5bf842dfe2f54
https://doi.org/10.1055/s-0031-1296559
https://doi.org/10.1055/s-0031-1296559
Autor:
Daniel Corsiero, Wolfgang Wendler, Hubert Heuer, Frank Girbig, Werner Kramer, Heiner Glombik, Stephan Petry, Claudia Weyland, Hans-Ludwig Schäfer
Publikováno v:
FEBS Letters. 487:293-297
To identify protein components of the intestinal cholesterol transporter, rabbit small intestinal brush border membrane vesicles were submitted to photoaffinity labeling using photoreactive derivatives of 2-azetidinone cholesterol absorption inhibito
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::feba5699c48d723146727daa45fc969a
https://doi.org/10.1016/s0014-5793(00)02372-3
https://doi.org/10.1016/s0014-5793(00)02372-3
Publikováno v:
European Journal of Pharmacology. 369:225-231
A novel model of allergic early and late-phase reaction in the airways of conscious guinea pigs was developed and the effect of established and novel antiasthmatic drugs on peak of immediate response, late phase response and associated inflammatory c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e9d5add4894060ae760399052fa164b
https://doi.org/10.1016/s0014-2999(99)00080-1
https://doi.org/10.1016/s0014-2999(99)00080-1
Autor:
Armin Hofmeister, Hubert Heuer, Uwe Schwahn, Petra Arndt, Michael Böhm, Klaus Wirth, Hartmut Ruetten, Wolfgang Linz, Wendelin Frick, Uwe Heinelt, Dominik Linz
Publikováno v:
Hypertension (Dallas, Tex. : 1979). 60(6)
High intestinal sodium absorption is one mechanism of hypertension and constipation. The sodium-proton-exchanger subtype 3 (NHE3) is an important mediator of sodium absorption in the gut. SAR218034 (SAR) is an orally nonabsorbable specific NHE3 inhib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2f6dce8287f703ab72d654f7053fd0f
https://pubmed.ncbi.nlm.nih.gov/23108657
https://pubmed.ncbi.nlm.nih.gov/23108657
Publikováno v:
Clinical Experimental Allergy. 24:682-689
Summary. The association between inflammatory cell influx, cell activation status and change of airway responsiveness to acelylcholine (ACh) after daily inhalation of ovalbumin (OA) in sensitized guinea–pigs was investigated. Starting 3 weeks after
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b17744d9f4513d5039a5ecac7755b120
https://doi.org/10.1111/j.1365-2222.1994.tb00973.x
https://doi.org/10.1111/j.1365-2222.1994.tb00973.x
Autor:
Juergen Meyer, Hubert Heuer, Manuela Schierenberg, Helmut F. Lohmann, Norbert Treese, Harald Darius
Publikováno v:
Lipids. 26:1381-1385
The purpose of the present study was to determine whether increased levels of platelet-activating factor (PAF) type activity can be detected in plasma from patients with septicemia and other diseases. A level of PAF below 0.5 ng/mL of plasma was cons
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58f85c9b64f3265afe97c6ad7ae31f4b
https://doi.org/10.1007/bf02536571
https://doi.org/10.1007/bf02536571
Autor:
Hubert Heuer
Publikováno v:
European Journal of Pharmacology. 199:157-163
The aim of this study was to examine the ability of the novel PAF (platelet-activating factor) antagonist WEB 2170 to inhibit active anaphylaxis in mice and guinea pigs. Previous studies with other PAF antagonists have given equivocal results This st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f21bf17635aa6b0583bfdb4786e6008
https://doi.org/10.1016/0014-2999(91)90453-w
https://doi.org/10.1016/0014-2999(91)90453-w
Publikováno v:
Biochemical Pharmacology. 41:657-668
The object of this review is to relate new developments in the field of platelet-activating factor (PAF) research to the problems of understanding. The cause and perhaps improving the therapy of thrombocytopenia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::748d5ad2c85acb4c8c01d59cc4675df1
https://doi.org/10.1016/0006-2952(91)90064-c
https://doi.org/10.1016/0006-2952(91)90064-c
Publikováno v:
Clinical Pharmacology and Therapeutics. 47:456-462
Recent research on asthma mediators has concentrated more and more on platelet-activating factor (PAF), which is one of the most potent bronchoconstrictors known thus far. Inhalant PAF challenge in healthy volunteers may provide a mean of testing PAF
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed81f487af104cba19261a03b40ef4f0
https://doi.org/10.1038/clpt.1990.57
https://doi.org/10.1038/clpt.1990.57