Zobrazeno 1 - 10
of 189
pro vyhledávání: '"Hubert Hackl"'
Autor:
Melina Amor, Malena Diaz, Valentina Bianco, Monika Svecla, Birgit Schwarz, Silvia Rainer, Anita Pirchheim, Laszlo Schooltink, Suravi Mukherjee, Gernot F. Grabner, Giangiacomo Beretta, Claudia Lamina, Giuseppe Danilo Norata, Hubert Hackl, Dagmar Kratky
Publikováno v:
Cardiovascular Diabetology, Vol 23, Iss 1, Pp 1-17 (2024)
Abstract Background Activation of brown adipose tissue (BAT) has gained attention due to its ability to dissipate energy and counteract cardiometabolic diseases (CMDs). Methods This study investigated the consequences of cold exposure on the BAT and
Externí odkaz:
https://doaj.org/article/820c312be79a46f2b97d9536a2e4a617
Autor:
Pablo Monfort-Lanzas, Elena Cristina Rusu, Lucia Parrakova, Cornelia A. Karg, Dorina-Elina Kernbichler, Dietmar Rieder, Peter Lackner, Hubert Hackl, Johanna M. Gostner
Publikováno v:
BMC Genomics, Vol 25, Iss 1, Pp 1-9 (2024)
Abstract Background Reverse transcription quantitative PCR (RT-qPCR) with intercalating dyes is one of the main techniques to assess gene expression levels used in basic and applied research as well as in diagnostics. However, primer design for RT-qP
Externí odkaz:
https://doaj.org/article/c069b496083a4183bb25200a49999a80
Autor:
Theresa Hautz, Hubert Hackl, Hendrik Gottschling, Raphael Gronauer, Julia Hofmann, Stefan Salcher, Bettina Zelger, Rupert Oberhuber, Benno Cardini, Annemarie Weissenbacher, Thomas Resch, Jakob Troppmair, Stefan Schneeberger
Publikováno v:
EBioMedicine, Vol 108, Iss , Pp 105330- (2024)
Summary: Background: A better understanding of the molecular events during liver normothermic machine perfusion (NMP) is warranted to develop a data-based approach for the identification of biomarkers representative of graft quality and posttransplan
Externí odkaz:
https://doaj.org/article/dabf014d3eea4d158514cdf8c8d27c59
Autor:
Marcus Bauer, Astrid Monecke, Hubert Hackl, Andreas Wilfer, Nadja Jaekel, Hendrik Bläker, Haifa Kathrin Al-Ali, Barbara Seliger, Claudia Wickenhauser
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionMyeloid sarcomas (MS) comprise rare extramedullary manifestations of myeloid neoplasms with poor patients’ outcome. While the clinical relevance of the tumor microenvironment (TME) is well established in many malignancies, there exists
Externí odkaz:
https://doaj.org/article/d57c7228eeb94e96aa3ee37df368358a
Autor:
Markus Haake, Beatrice Haack, Tina Schäfer, Patrick N. Harter, Greta Mattavelli, Patrick Eiring, Neha Vashist, Florian Wedekink, Sabrina Genssler, Birgitt Fischer, Julia Dahlhoff, Fatemeh Mokhtari, Anastasia Kuzkina, Marij J. P. Welters, Tamara M. Benz, Lena Sorger, Vincent Thiemann, Giovanni Almanzar, Martina Selle, Klara Thein, Jacob Späth, Maria Cecilia Gonzalez, Carmen Reitinger, Andrea Ipsen-Escobedo, Kilian Wistuba-Hamprecht, Kristin Eichler, Katharina Filipski, Pia S. Zeiner, Rudi Beschorner, Renske Goedemans, Falk Hagen Gogolla, Hubert Hackl, Rogier W. Rooswinkel, Alexander Thiem, Paula Romer Roche, Hemant Joshi, Dirk Pühringer, Achim Wöckel, Joachim E. Diessner, Manfred Rüdiger, Eugen Leo, Phil F. Cheng, Mitchell P. Levesque, Matthias Goebeler, Markus Sauer, Falk Nimmerjahn, Christine Schuberth-Wagner, Stefanie von Felten, Michel Mittelbronn, Matthias Mehling, Andreas Beilhack, Sjoerd H. van der Burg, Angela Riedel, Benjamin Weide, Reinhard Dummer, Jörg Wischhusen
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Abstract Immune checkpoint blockade therapy is beneficial and even curative for some cancer patients. However, the majority don’t respond to immune therapy. Across different tumor types, pre-existing T cell infiltrates predict response to checkpoin
Externí odkaz:
https://doaj.org/article/5207814fce1e426b9e431dafa4d554e4
Autor:
Stefan Koeck, Arno Amann, Johan Kern, Marit Zwierzina, Edith Lorenz, Sieghart Sopper, Heinz Zwierzina, Finn Mildner, Martina Sykora, Susanne Sprung, Hubert Hackl, Florian Augustin, Hubert T. Maier, Andreas Pircher, Georg Pall, Dominik Wolf, Gabriele Gamerith
Publikováno v:
OncoImmunology, Vol 12, Iss 1 (2023)
ABSTRACTCancer associated fibroblasts (CAF) are known to orchestrate multiple components of the tumor microenvironment, whereas the influence of the whole stromal-fibroblast compartment is less understood. Here, an extended stromal fibroblast signatu
Externí odkaz:
https://doaj.org/article/b8859450d2444344a0b717d8fca9bf03
Autor:
Renate Pichler, Gabriel Diem, Hubert Hackl, Jiří Koutník, Laura S. Mertens, David D`Andrea, Benjamin Pradere, Francesco Soria, Andrea Mari, Ekaterina Laukhtina, Wojciech Krajewski, Jeremy Yuen-Chun Teoh, Francesco Del Guidice, Marco Moschini, Martin Thurnher, Wilfried Posch
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BCG is the most efficient adjuvant therapy for high-risk, non-muscle-invasive bladder cancer (NMIBC). Both innate and adaptive immune responses have been implicated in BCG-mediated effects. BCG vaccination can boost innate immune responses via traine
Externí odkaz:
https://doaj.org/article/3292851d0d8e44c394d83330342e1654
Autor:
Patrick Starlinger, Laura Brunnthaler, Chantal McCabe, David Pereyra, Jonas Santol, Jessica Steadman, Matthias Hackl, Susanna Skalicky, Hubert Hackl, Raphael Gronauer, Daniel O’Brien, Renate Kain, Petra Hirsova, Gregory J. Gores, Chen Wang, Thomas Gruenberger, Rory L. Smoot, Alice Assinger
Publikováno v:
JHEP Reports, Vol 5, Iss 4, Pp 100683- (2023)
Background & Aims: Although extensive experimental evidence on the process of liver regeneration exists, in humans, validation is largely missing. However, liver regeneration is critically affected by underlying liver disease. Within this project, we
Externí odkaz:
https://doaj.org/article/4b427ef4df024f639af616e5875afdfb
Autor:
Anita Pirabe, Sabine Frühwirth, Laura Brunnthaler, Hubert Hackl, Anna Schmuckenschlager, Waltraud C. Schrottmaier, Alice Assinger
Publikováno v:
Cells, Vol 12, Iss 19, p 2419 (2023)
Aging is a multifaceted process that unfolds at both the individual and cellular levels, resulting in changes in platelet count and platelet reactivity. These alterations are influenced by shifts in platelet production, as well as by various environm
Externí odkaz:
https://doaj.org/article/dcff0abb72a3461f806cf4152377ff51
Autor:
Saskia V. Vijver, Sarah Danklmaier, Lisa Pipperger, Raphael Gronauer, Gabriel Floriani, Hubert Hackl, Krishna Das, Guido Wollmann
Publikováno v:
Frontiers in Immunology, Vol 13 (2023)
Oncolytic viruses are currently tested as a novel platform for cancer therapy. These viruses preferentially replicate in and kill malignant cells. Due to their microbial origin, treatment with oncolytic viruses naturally results in anti-viral respons
Externí odkaz:
https://doaj.org/article/3b96f4f2fe924248b1bdfa54a200326f