Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Hubert François Gaertner"'
Autor:
Peter Vollenweider, Nicolas Vuilleumier, Gérard Waeber, François Mach, Fabrizio Montecucco, Nathalie Satta, Karim J. Brandt, Fabienne Burger, Julien Virzi, Oliver Hartley, Pedro Marques-Vidal, Hubert François Gaertner, Panagiotis Antiochos, Sabrina Pagano
Publikováno v:
Clinical & Translational Immunology, Vol 9, Iss 12, Pp n/a-n/a (2020)
Clinical & translational immunology, Vol. 9, No 12 (2020) P. e1220
Clinical & Translational Immunology
Clinical & translational immunology, vol. 9, no. 12, pp. e1220
Clinical & translational immunology, Vol. 9, No 12 (2020) P. e1220
Clinical & Translational Immunology
Clinical & translational immunology, vol. 9, no. 12, pp. e1220
Objectives Autoantibodies against apolipoprotein A1 (anti‐apoA1 IgGs) and its C‐terminal region (cter apoA1) have emerged as an independent biomarker for cardiovascular disease. Cter apoA1 mimetic peptides were shown to reverse the deleterious an
Autor:
He Tian, Jennifer C. Peeler, Manija A. Kazmi, Thomas Huber, Mizuho Horioka, Alexandre Fürstenberg, Oliver Hartley, Thomas P. Sakmar, Emily Lorenzen, Yamina A. Berchiche, Carlos A. Rico, Hubert François Gaertner
The chemokine receptor CCR5 is a drug target to prevent transmission of HIV/AIDS. We studied four analogs of the native chemokine RANTES (CCL5) that have anti-HIV potencies of around 25 pM, which is more than four orders-of-magnitude higher than that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60272af1e30def26b3c4dbced0d36b5f
https://doi.org/10.1101/575795
https://doi.org/10.1101/575795
Autor:
Manija A. Kazmi, Mizuho Horioka, Thomas Huber, Jennifer C. Peeler, He Tian, Thomas P. Sakmar, Alexandre Fürstenberg, Oliver Hartley, Yamina A. Berchiche, Carlos A. Rico, Hubert François Gaertner, Emily Lorenzen
Publikováno v:
Biophys J
Biophysical Journal, Vol. 117, No 5 (2019) pp. 903-919
Biophysical Journal, Vol. 117, No 5 (2019) pp. 903-919
The chemokine receptor CCR5 is a drug target to prevent transmission of HIV/AIDS. We studied four analogs of the native chemokine regulated, on activation, normal T-cell-expressed, and secreted (RANTES) (CCL5) that have anti-HIV potencies of around 2
Autor:
Madiha Derouazi, Else-Marit Suso-Inderberg, Hubert François Gaertner, Pierre-Yves Dietrich, Paul R. Walker, Wilma Di Berardino-Besson, Sébastien Wälchli, Oliver Hartley, Elodie Belnoue, Fabrice Cerini, Andres M. Salazar, Stéphane König, Susanna Carboni, Isabelle Dunand-Sauthier
Publikováno v:
Molecular Therapy, Vol. 24, No 9 (2016) pp. 1675-1685
Cell penetrating peptides (CPPs) from the protein ZEBRA are promising candidates to exploit in therapeutic cancer vaccines, since they can transport antigenic cargos into dendritic cells and induce tumor-specific T cells. Employing CPPs for a given c
Autor:
Hanno Langen, Michelle Butterfield, Oliver Hartley, Nicolas Vuilleumier, Paul Cutler, Priscila Camillo Teixeira, Sabrina Pagano, Axel Ducret, Philippe Ferber, Hubert François Gaertner
Publikováno v:
Journal of Biological Chemistry, Vol. 289, No 41 (2014) pp. 28249-59
The Journal of Biological Chemistry
The Journal of biological chemistry
The Journal of Biological Chemistry
The Journal of biological chemistry
Background: Autoantibodies to apoA-I can be considered markers and mediators of cardiovascular disease. Results: Methodologies for identification of human apoA-I epitopes are described. Two novel immunoreactive peptides were recognized by autoantibod
Autor:
Amrita Ahluwalia, Irène Rossitto-Borlat, Elizabeth G. Wood, Pedro R. Cutillas, Jale Yuzugulen, Nimesh S. A. Patel, Hubert François Gaertner, Inmaculada C Villar, Roger Corder, Keith Rose, Oliver Hartley, James Jegard, Julie A. Douthwaite
Publikováno v:
Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-15 (2017)
Scientific Reports, Vol. 7, No 1 (2017) P. 4956
Scientific Reports, Vol 7, Iss 1, Pp 1-15 (2017)
Scientific Reports, Vol. 7, No 1 (2017) P. 4956
Endothelin-1 (ET-1) is involved in the pathogenesis of cardiac and renal diseases, and in the progression of tumour growth in cancer, but current diagnosis and treatment remain inadequate. Peptides derived from the 212 amino acid precursor preproendo
Autor:
Fabrice Cerini, Guy Gorochov, Karim Dorgham, Irène Rossitto-Borlat, Hubert François Gaertner, Oliver Hartley, Astrid Melotti
Publikováno v:
Chemokines
Chemokines, pp.47-72, 2016, ⟨10.1016/bs.mie.2015.09.014⟩
Chemokines, pp.47-72, 2016, ⟨10.1016/bs.mie.2015.09.014⟩
Phage display technology, which allows extremely rare ligands to be selected from libraries of variants according to user-defined selection criteria, has made a huge impact on the life sciences. In this chapter, we describe phage display methods for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cc3f665466687fe48812e2ebbdb1b19
https://hal.archives-ouvertes.fr/hal-02480548
https://hal.archives-ouvertes.fr/hal-02480548
Autor:
Stephan B Abramson, Nico Callewaert, Ilya I. Tolstorukov, Michael M. Meagher, Jay C. Harner, Hubert François Gaertner, Anthony R Sump, Dustin J Peterson, Scott Brown, Robin E. Offord, Bram Laukens, Robert C Sealock, Knut Madden, Fabrice Cerini, Scott K. Johnson, John T Harms, Oliver Hartley, Anna M. Oommen
Publikováno v:
Protein Expression and Purification, Vol. 119 (2016) pp. 1-10
Protein Expression and Purification
PROTEIN EXPRESSION AND PURIFICATION
Protein Expression and Purification
PROTEIN EXPRESSION AND PURIFICATION
In the continued absence of an effective anti-HIV vaccine, approximately 2 million new HIV infections occur every year, with over 95% of these in developing countries. Calls have been made for the development of anti-HIV drugs that can be formulated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0ed5918e72bcd53b6ac92ea4a6c44e4
https://archive-ouverte.unige.ch/unige:88663
https://archive-ouverte.unige.ch/unige:88663
Autor:
Philippe Favreau, Rolf Boelens, Jordi Molgó, Hubert François Gaertner, Daniel Bertrand, Jan Tytgat, Enrico Leipold, Henry G. Hocking, Ludovic Carlier, Dieter D' hoedt, Reto Stöcklin, Marco Cordova, Sébastien Schlumberger, René Markgraf, Oliver Hartley, Evelyne Benoit, Marianne Paolini-Bertrand, Stefan H. Heinemann
Publikováno v:
British Journal of Pharmacology. 166:1654-1668
BACKGROUND AND PURPOSE The µ-conopeptide family is defined by its ability to block voltage-gated sodium channels (VGSCs), a property that can be used for the development of myorelaxants and analgesics. We characterized the pharmacology of a new µ-c
Autor:
Oliver Hartley, Gabriel Kuenzi, Michelangelo Foti, Jean-Michel Escola, Hubert François Gaertner
Publikováno v:
Journal of Biological Chemistry. 285:41772-41780
CC chemokine receptor 5 (CCR5), the major HIV coreceptor, is a G protein-coupled receptor (GPCR) involved in cell activation and migration in response to chemokines. Blockade of CCR5 is an effective anti-HIV strategy, and potent anti-HIV chemokine an