Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Hubert E. Appert"'
Publikováno v:
Journal of Surgical Oncology. 61:100-105
Oncogenes, tumor suppressor genes, and growth factors are being explored as to their role in the initiation and progression of most neoplasms, but little information exists on the expression of oncoproteins or growth factors in adenocarcinoma of the
Publikováno v:
The Journal of surgical research. 110(2)
Background. Matrix metalloproteinases (MMPs) have been implicated as possible mediators of invasion and metastasis in some cancers. Our objective was to investigate which MMPs were constitutively expressed in breast tumor cells versus those that coul
Publikováno v:
The Journal of surgical research. 110(1)
Background. Extracellular matrix (ECM) components, such as vitronectin and fibronectin, have been shown to enhance the metastatic potential of breast cancer cells. We hypothesized that ECM binding to integrin receptors on breast cancer cells influenc
Publikováno v:
World journal of gastroenterology. 7(1)
Development of drug-resistance to chemotherapy and subsequent metastasis of tumor are primarily responsible for treatment failure and the death from cancer. There have been many previous studies on the relationship between expression of multidrug res
Publikováno v:
The Journal of surgical research. 99(2)
Background. Pancreatic adenocarcinoma (PAC) is generally refractory to most chemotherapeutic agents, including docetaxel (Taxotere; TXT). Specific mechanisms for TXT-related drug resistance in PAC have not been defined. The hypothesis of this study w
Autor:
Edgar D. Staren, Hubert E. Appert, Xinqun Yang, John M. Howard, John E Bartsch, Takeshi Iwamura
Publikováno v:
The Journal of surgical research. 98(1)
Background. Previous investigations have suggested that expression of matrix metalloproteinases (MMPs) may be related to increased invasiveness of various tumors. This study evaluated a possible relation between pancreatic tumor cell invasiveness and
Autor:
Peter J. Delves, Eric G. Berger, Jeremy J. Keusch, Peter M. Lydyard, George Panayotou, Martine Malissard, Hubert E. Appert
Publikováno v:
Carbohydrate research. 313(1)
The epitopes present on beta-(1-->4)-galactosyltransferase-1 (beta 4Gal-T1) have been explored using a panel of monoclonal antibodies (mAbs) raised against the soluble form of the human enzyme. Reactivity of the antibodies with site-specific and trun
Publikováno v:
Biochemical and biophysical research communications. 231(2)
Matrigel invasion assays were used to characterize the invasive abilities of five breast cancer cell lines. Reverse Transcription Polymerase Chain Reaction (RT-PCR) was used to detect the differential gene expression of estrogen receptor (ER), E-cadh
Publikováno v:
International journal of pancreatology : official journal of the International Association of Pancreatology. 17(1)
For the purpose of determining the prognostic significance of HER2/neu oncogene in pancreatic and ampullary cancers, 21 pancreatic cancers of ductal origin and six cancers of the ampulla of Vater were studied immunohistochemically using the monoclona
Autor:
Liyin Zhu, Chuanyan Mao, John M. Howard, Paul Schaefer, Hubert E. Appert, Daniel J. Hanson, Justo M. Dominguez, Paul Carter, Kitai Kim
Publikováno v:
Surgery. 117(1)
Background. Three cases of islet cell tumors of the pancreas with hypercalcemia were studied, and 16 similar cases have been found in a 25-year review of the English-language literature. The purpose of the study was to review the cause of the hyperca