Zobrazeno 1 - 10
of 334
pro vyhledávání: '"Hubert, Kalbacher"'
Autor:
Layla Drwesh, Benjamin Heim, Max Graf, Linda Kehr, Lea Hansen-Palmus, Mirita Franz-Wachtel, Boris Macek, Hubert Kalbacher, Johannes Buchner, Doron Rapaport
Publikováno v:
eLife, Vol 11 (2022)
Signal-anchored (SA) proteins are anchored into the mitochondrial outer membrane (OM) via a single transmembrane segment at their N-terminus while the bulk of the proteins is facing the cytosol. These proteins are encoded by nuclear DNA, translated o
Externí odkaz:
https://doaj.org/article/7dbf58e4eeb745418de493b904849420
Publikováno v:
ACS Omega, Vol 6, Iss 10, Pp 7181-7185 (2021)
Externí odkaz:
https://doaj.org/article/d68423ae8d2a46b8a745202b6444dd8e
Publikováno v:
PLoS ONE, Vol 17, Iss 4 (2022)
The serine proteases neutrophil elastase (NE), proteinase 3 (PR3), cathepsin G (CatG), and neutrophil serine protease 4 (NSP4) are secreted by activated neutrophils as a part of the innate immune response against invading pathogens. However, these se
Externí odkaz:
https://doaj.org/article/4fcec229732040fc81c42620302945a5
Autor:
Franziska Herster, Zsofia Bittner, Nathan K. Archer, Sabine Dickhöfer, David Eisel, Tatjana Eigenbrod, Thomas Knorpp, Nicole Schneiderhan-Marra, Markus W. Löffler, Hubert Kalbacher, Tim Vierbuchen, Holger Heine, Lloyd S. Miller, Dominik Hartl, Lukas Freund, Knut Schäkel, Martin Heister, Kamran Ghoreschi, Alexander N. R. Weber
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Antimicrobial peptide LL37 can bind nucleic acids and potentiate their sensing by endosomal TLRs. Here the authors show that LL37 binds to RNA from neutrophil extracellular traps (NETs), which amplifies inflammation and production of more LL37 and NE
Externí odkaz:
https://doaj.org/article/ea97f7082ce74177a2af8db079fd79c4
Publikováno v:
Molecules, Vol 27, Iss 18, p 5817 (2022)
The prevalence of novel SARS-CoV-2 variants is also accompanied by an increased turnover rate and additional cleavage sites at the positions necessary for priming the Spike (S) protein. Of these priming sites, the proteolytically sensitive polybasic
Externí odkaz:
https://doaj.org/article/2e5fcf9e0bfe478fa29d79d9a9a00551
Autor:
Katharina Bitschar, Birgit Sauer, Jule Focken, Hanna Dehmer, Sonja Moos, Martin Konnerth, Nadine A. Schilling, Stephanie Grond, Hubert Kalbacher, Florian C. Kurschus, Friedrich Götz, Bernhard Krismer, Andreas Peschel, Birgit Schittek
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Lugdunin is a peptide antibiotic produced by the skin commensal Staphylococcus lugdunensis. Here, the authors show that lugdunin reduces Staphylococcus aureus colonization in human keratinocytes and mouse skin by inducing the expression of human LL-3
Externí odkaz:
https://doaj.org/article/cdeeef7531844cd4aa56780138aa628c
Autor:
Anastasios I. Birmpilis, Antonios Paschalis, Apostolis Mourkakis, Panayiota Christodoulou, Ioannis V. Kostopoulos, Elina Antimissari, Georgia Terzoudi, Alexandros G. Georgakilas, Christina Armpilia, Panagiotis Papageorgis, Efstathios Kastritis, Evangelos Terpos, Meletios A. Dimopoulos, Hubert Kalbacher, Evangelia Livaniou, Maria-Ioanna Christodoulou, Ourania E. Tsitsilonis
Publikováno v:
Cells, Vol 11, Iss 9, p 1415 (2022)
The new and increasingly studied concept of immunogenic cell death (ICD) revealed a previously unknown perspective of the various regulated cell death (RCD) modalities, elucidating their immunogenic properties and rendering obsolete the notion that i
Externí odkaz:
https://doaj.org/article/a0d252a316844a5fb71c302cd1054f61
Autor:
Margarita Skopeliti, David Toukli, Eleftheria Klagkou, Anastasios I. Birmpilis, Panagiotis Vitsos, Themis Gkraikou, Wolfgang Voelter, Hubert Kalbacher, Nikolaos Angelis, Pinelopi Samara, Niki Kappa, Ourania E. Tsitsilonis, Persefoni Klimentzou, Nikos E. Papaioannou, Elena Alyfanti, Spiridoula Nikou, Kyriaki Ioannou, Meletios-Athanasios Dimopoulos, Chrysoula-Evangelia Karachaliou, Nikolaos G. Gavalas, Ioannis Kostopoulos, Ioannis F. Voutsas, Lillian Williams, Evangelia Livaniou, Aristotelis Bamias
Publikováno v:
Current Medicinal Chemistry. 29:6463-6478
Background: Members of the α-thymosin family have long been studied for their immunostimulating properties. Among them, the danger-associated molecular patterns (DAMPs) prothymosin α (proTα) and its C-terminal decapeptide proTα(100–109) have be
Autor:
Chrysoula-Evangelia Karachaliou, Ioannis V. Kostopoulos, Vyronia Vassilakopoulou, Persefoni Klimentzou, Maria Paravatou-Petsotas, Wolfgang Voelter, Hubert Kalbacher, Christos Zikos, Ourania Tsitsilonis, Evangelia Livaniou
Publikováno v:
Heliyon, Vol 5, Iss 10, Pp e02616- (2019)
Prothymosin alpha (ProTα) is a highly conserved polypeptide (109 amino acids in humans) with diagnostic and therapeutic potential; ProTα exerts intra- and extra-cellular biological functions associated with cell proliferation, apoptosis and immune
Externí odkaz:
https://doaj.org/article/ade616ea68eb4a20baa3536dbfd68062
Autor:
Markéta Kovářová, Hubert Kalbacher, Andreas Peter, Hans-Ulrich Häring, Triantafyllos Didangelos, Norbert Stefan, Andreas Birkenfeld, Erwin Schleicher, Konstantinos Kantartzis
Publikováno v:
Journal of Clinical Medicine, Vol 10, Iss 3, p 411 (2021)
The hepatokine fetuin A (Fet A) has been associated with diverse pathological states such as insulin resistance, type 2 diabetes, macrovascular disease, and systemic ectopic and vascular calcification. Fet A may also play a role in tumor growth and m
Externí odkaz:
https://doaj.org/article/549f32ce86064c33aab7eb966420d0f9