Functional estrogen receptor signal transduction pathway activity and antihormonal therapy response in low-grade ovarian carcinoma

Autor: Cynthia S. E. Hendrikse, Phyllis van der Ploeg, Nienke M. A. van de Kruis, Jody H. C. Wilting, Floor Oosterkamp, Pauline M. M. Theelen, Christianne A. R. Lok, Joanne A. de Hullu, Huberdina P. M. Smedts, M. Caroline Vos, Brenda M. Pijlman, Loes F. S. Kooreman, Johan Bulten, Marjolein H. F. M. Lentjes‐Beer, Steven L. Bosch, Anja van de Stolpe, Sandrina Lambrechts, Ruud L. M. Bekkers, Jurgen M. J. Piek

Publikováno v: Cancer, 129(9), 1361-1371. Wiley
Cancer, 129, 9, pp. 1361-1371
Cancer, 129, 1361-1371

Contains fulltext : 291887.pdf (Publisher’s version ) (Open Access) BACKGROUND: Advanced low-grade ovarian carcinoma (LGOC) is difficult to treat. In several studies, high estrogen receptor (ER) protein expression was observed in patients with LGOC

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4e78328b415fa76014a1b9e212d0c2b
https://cris.maastrichtuniversity.nl/en/publications/9e6e8598-eebd-4996-aa9c-7406328c4dbe

A derangement of the maternal lipid profile is associated with an elevated risk of congenital heart disease in the offspring

Autor: O. Valkenburg, Joop S.E. Laven, Régine P.M. Steegers-Theunissen, Marinus J.C. Eijkemans, Huberdina P. M. Smedts, E.M. van Uitert, Jan Lindemans, E.A.P. Steegers

Publikováno v: Nutrition, Metabolism and Cardiovascular Diseases, 22(6), 477-485. Elsevier

Maternal hyperglycaemia and hyperhomocysteinaemia are risk factors for congenital heart disease (CHD). These metabolic derangements and deranged lipid levels are associated with adult cardiovascular disease. We examined whether maternal lipid levels

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::818c6f42375f60763ce1f52dd4195055
https://doi.org/10.1016/j.numecd.2010.07.016

High maternal vitamin E intake by diet or supplements is associated with congenital heart defects in the offspring

Autor: Mark F. Wildhagen, M. Rakhshandehroo, E.A.P. Steegers, Anna C. Verkleij-Hagoort, J.H.M. de Vries, Régine P.M. Steegers-Theunissen, Huberdina P. M. Smedts

Publikováno v: BJOG : an international journal of obstetrics and gynaecology 116 (2009) 3
BJOG : an international journal of obstetrics and gynaecology, 116(3), 416-423
Bjog-An International Journal of Obstetrics and Gynaecology, 116(3), 416-423. Wiley-Blackwell Publishing Ltd
BJOG-an International Journal Of Obstetrics And Gynaecology, 116(3), 416-423. Wiley

Objective To study associations between maternal dietary and supplement intake of antioxidants vitamin E, retinol and congenital heart defects (CHDs). Design Case–control study. Setting Erasmus MC, University Medical Center Rotterdam, the Netherlan

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a65606136186565b92be6f0bad518242
https://doi.org/10.1111/j.1471-0528.2008.01957.x

Maternal intake of fat, riboflavin and nicotinamide and the risk of having offspring with congenital heart defects

Autor: Jeanne H.M. de Vries, Anna C. Verkleij-Hagoort, Régine P.M. Steegers-Theunissen, Huberdina P. M. Smedts, Eric A.P. Steegers, Jaap Ottenkamp, Maryam Rakhshandehroo

Publikováno v: European Journal of Nutrition, 47(7), 357-365. D. Steinkopff-Verlag
European Journal of Nutrition, 47(7), 357-365
European Journal of Nutrition 47 (2008) 7
European journal of nutrition, 47(7), 357-365. D. Steinkopff-Verlag

With the exception of studies on folic acid, little evidence is available concerning other nutrients in the pathogenesis of congenital heart defects (CHDs). Fatty acids play a central role in embryonic development, and the B-vitamins riboflavin and n

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90a5d659bef0ea0f4923743bc6cd5aa8
https://pure.eur.nl/en/publications/64670b12-5bc0-45e0-bda4-51a20f56ccd7