Výsledky vyhledávání - "Huber-Bruning O"

Autor: Huber-Bruning O, Nietfeld Jj, Bÿlsma Jw

Publikováno v: Proteoglycans ISBN: 9783034875479

Cytokines play an important regulatory role in the metabolism of proteoglycans. Proteoglycans are found in plasma membranes, but predominantly in the extra-cellular matrix. In the latter they are quantitatively and qualitatively essential components.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9d26f93a95e5377d8ac42adaa70807b5
https://doi.org/10.1007/978-3-0348-7545-5_13

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Osteoarthritic human cartilage is more sensitive to transforming growth factor beta than is normal cartilage

Autor: Lafeber, F. P., Vander Kraan, P. M., Huber-Bruning, O., Vanden Berg, W. B., Bijlsma, J. W.

Publikováno v: British journal of rheumatology, 32(4), 281-286. Oxford University Press

Osteoarthritis is a degenerative joint disease, characterized by the destruction of the articular cartilage. One of the first changes in the osteoarthritic articular cartilage is a reduction in proteoglycan content. In this study we demonstrate that

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::af5193a27b4c373c77d5f18941349579
https://pure.amc.nl/en/publications/osteoarthritic-human-cartilage-is-more-sensitive-to-transforming-growth-factor-beta-than-is-normal-cartilage(b0f72767-d242-4674-a8cd-03c2d32c4485).html

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Human osteoarthritic cartilage is synthetically more active but in culture less vital than normal cartilage

Autor: Lafeber, F. P., van Roy, H., Wilbrink, B., Huber-Bruning, O., Bijlsma, J. W.

Publikováno v: Journal of rheumatology, 19(1), 123-129. Journal of Rheumatology

The proteoglycan turnover of human osteoarthritic (OA) cartilage was compared to that of normal (N) cartilage. The cartilage was obtained postmortem from human femoral knee condyles. Short term cultures were compared to longterm cultures, and proteog

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::f382fab7d9bad1dd37d46321fa165e24
https://pure.amc.nl/en/publications/human-osteoarthritic-cartilage-is-synthetically-more-active-but-in-culture-less-vital-than-normal-cartilage(180a1555-9e4e-4413-bb06-e6141e856be9).html

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Local changes in proteoglycan synthesis during culture are different for normal and osteoarthritic cartilage

Autor: Lafeber, F. P., van der Kraan, P. M., van Roy, H. L., Vitters, E. L., Huber-Bruning, O., van den Berg, W. B., Bijlsma, J. W.

Publikováno v: American journal of pathology, 140(6), 1421-1429. Elsevier Inc.

Proteoglycan synthesis of mild-to-moderate osteoarthritic human knee cartilage was compared with that of normal cartilage of the same donor. Immediately after cartilage was obtained, the synthesis rate of proteoglycans was higher for osteoarthritic c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::31e79356df15c795ec7e116939b4792b
https://pure.amc.nl/en/publications/local-changes-in-proteoglycan-synthesis-during-culture-are-different-for-normal-and-osteoarthritic-cartilage(48828be7-ed75-4b04-89ed-550281843c0c).html

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Role of TNF alpha, in relation to IL-1 and IL-6 in the proteoglycan turnover of human articular cartilage

Autor: Wilbrink, B., Nietfeld, J. J., den Otter, W., van Roy, J. L., Bijlsma, J. W., Huber-Bruning, O.

Publikováno v: British journal of rheumatology, 30(4), 265-271. Oxford University Press

In both young and old human articular cartilage explants, TNF alpha induced a concentration-dependent, reversible suppression of the proteoglycan (PG) synthesis. Young cartilage was more sensitive to TNF alpha than old cartilage: 50% suppression of P

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::bd399334aba118238d4417ecdb003a2e
https://pure.amc.nl/en/publications/role-of-tnf-alpha-in-relation-to-il1-and-il6-in-the-proteoglycan-turnover-of-human-articular-cartilage(a43b1919-2472-4ad7-a660-17ca1cfef24d).html

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Relation between patients' own health assessment and clinical and laboratory findings in rheumatoid arthritis

Autor: Bijlsma, J. W., Huiskes, C. J., Kraaimaat, F. W., Vanderveen, M. J., Huber-Bruning, O.

Publikováno v: Journal of rheumatology, 18(5), 650-653. Journal of Rheumatology

Health status encompasses not only physical aspects, but also psychological and social aspects. A multidimensional health status questionnaire was used in 69 Dutch patients with rheumatoid arthritis to assess their physical, psychological and social

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::1bc166185805af762737c3847932ca46
https://pure.amc.nl/en/publications/relation-between-patients-own-health-assessment-and-clinical-and-laboratory-findings-in-rheumatoid-arthritis(3b225ba4-a3fd-4f75-927c-73f78154e792).html

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Mycobacterial antigens stimulate rheumatoid mononuclear cells to cartilage proteoglycan depletion

Autor: Wilbrink, B., Bijlsma, J. W., Huber-Bruning, O., van Roy, J. L., den Otter, W., van Eden, W.

Publikováno v: Journal of rheumatology, 17(4), 532-537. Journal of Rheumatology

In a coculture with porcine articular cartilage explants unstimulated blood mononuclear cells (BMC) from patients with rheumatoid arthritis (RA), but not from healthy controls, induced proteoglycan depletion of dead cartilage. Specific stimulation of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::0d513124a8952453635fa8229b7c6510
https://pure.amc.nl/en/publications/mycobacterial-antigens-stimulate-rheumatoid-mononuclear-cells-to-cartilage-proteoglycan-depletion(838cb962-0a24-4096-b53f-7ad7373eab61).html

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