Targeting Beta-Amyloid at the CSF: A New Therapeutic Strategy in Alzheimer’s Disease

Autor: Manuel Menendez-Gonzalez, Huber S. Padilla-Zambrano, Gabriel Alvarez, Estibaliz Capetillo-Zarate, Cristina Tomas-Zapico, Agustin Costa

Publikováno v: Frontiers in Aging Neuroscience, Vol 10 (2018)

Although immunotherapies against the amyloid-β (Aβ) peptide tried so date failed to prove sufficient clinical benefit, Aβ still remains the main target in Alzheimer’s disease (AD). This article aims to show the rationale of a new therapeutic str

Externí odkaz: https://doaj.org/article/ccbb91f7f49c407cb2fc1b9f2aef5906

Management of subdural chronic hematoma in Colombia

Autor: Marticela Morales-Cabeza, Amit Agrawal, Gabriel Alcala-Cerra, Huber S. Padilla-Zambrano, Andres M. Rubiano, Alfonso Pacheco-Hernandez, Luis Gabriel Moscote-Salazar, Hernando Alvis-Miranda, Luis Rafael Moscote-Salazar

Publikováno v: Romanian Neurosurgery, Vol 31, Iss 2 (2017)

Chronic subdural hematoma is a growing neurological pathology, especially in older people. Thus, describing how this entity is approached in Colombia is of great importance because it allows to evaluate and contrast this approach with that of other c

Externí odkaz: https://doaj.org/article/214297c8f3dd4f2da9d32a90296d1c58

Clearing Extracellular Alpha-Synuclein from Cerebrospinal Fluid: A New Therapeutic Strategy in Parkinson’s Disease

Autor: Manuel Menéndez-González, Huber S. Padilla-Zambrano, Cristina Tomás-Zapico, Benjamin Fernández García

Publikováno v: Brain Sciences, Vol 8, Iss 4, p 52 (2018)

This concept article aims to show the rationale of targeting extracellular α-Synuclein (α-Syn) from cerebrospinal fluid (CSF) as a new strategy to remove this protein from the brain in Parkinson’s disease (PD). Misfolding and intracellular aggreg

Externí odkaz: https://doaj.org/article/91a88a9cda7042938e55c691993bb275

The Prion-like Properties of Amyloid-beta Peptide and Tau: Is there Any Risk of Transmitting Alzheimer's Disease During Neurosurgical Interventions?

Autor: Andrés E. Sibaja-Perez, Luis Rafael Moscote-Salazar, Ezequiel Garcia-Ballestas, Amit Agrawal, Manuel Menéndez-González, Gabriel Alexander Quiñones-Ossa, Huber S. Padilla-Zambrano

Publikováno v: Repositorio U. El Bosque
Universidad El Bosque
instacron:Universidad El Bosque

Recent studies have recognized similarities between the peptides involved in the neuropathology of Alzheimer’s disease and prions. The Tau protein and the Amyloid β peptide represent the theoretical pillars of Alzheimer’s disease development. It

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01c6f004beb735abeef24afdc245d934
https://doi.org/10.2174/1567205017666201204164220

Current Status of Indications, Timing, Management, Complications, and Outcomes of Tracheostomy in Traumatic Brain Injury Patients

Autor: Gabriel Alexander Quiñones-Ossa, R Hollandx, J Gerber, Luis Rafael Moscote-Salazar, Ranabir Pal, Jenny Ruiz, Yeider A. Durango-Espinosa, Huber S. Padilla-Zambrano, Amrita Ghosh, Sagar Galwankar, Amit Agrawal

Publikováno v: Journal of Neurosciences in Rural Practice
Journal of Neurosciences in Rural Practice, Vol 11, Iss 02, Pp 222-229 (2020)
Repositorio U. El Bosque
Universidad El Bosque
instacron:Universidad El Bosque

Tracheostomy is the commonest bedside surgical procedure performed on patients needing mechanical ventilation with traumatic brain injury (TBI). The researchers made an effort to organize a narrative review of the indications, timing, management, com

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d89487a0e7ae923e4cb0e81d48af410a
http://europepmc.org/articles/PMC7195963