Zobrazeno 1 - 10
of 160
pro vyhledávání: '"Huba Kalász"'
Autor:
Ernest Adeghate, Crystal M. D’Souza, Zulqarnain Saeed, Saeeda Al Jaberi, Saeed Tariq, Huba Kalász, Kornélia Tekes, Ernest A. Adeghate
Publikováno v:
Biology, Vol 10, Iss 7, p 621 (2021)
Nociceptin (NC) consists of 17 amino acids (aa) and takes part in the processing of learning and memory. The role of NC in the induction of endogenous antioxidants in still unclear. We examined the effect of NC on the expression of endogenous antioxi
Externí odkaz:
https://doaj.org/article/28aa97d2335544c189a8f9a062cf04fb
Publikováno v:
Molecules, Vol 25, Iss 5, p 1250 (2020)
Our aim was to find chlorine-substituted antidotes against organophosphate poisoning and compare their pharmacokinetics to their parent compound, K-203. White male Wistar rats were intramuscularly injected with K-203, K-867 or K-870. Serum, brain, ki
Externí odkaz:
https://doaj.org/article/c21957877b1f487383940831ab53e8d6
Autor:
Huba Kalász
Publikováno v:
Current Medicinal Chemistry. 30:3831-3831
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::75b846791e17d8d3773675ea304446fd
https://doi.org/10.2174/092986733034230504145607
https://doi.org/10.2174/092986733034230504145607
Autor:
Huba Kalász, Kornélia Tekes, György Bátor, Jennifer Adeghate, Ernest Adeghate, Ferenc Darvas, József Fűrész, Gellért Karvaly
Publikováno v:
The Open Medicinal Chemistry Journal. 15:17-27
Background: The widespread use of organophosphorus compounds in agriculture and their existence in some military arsenals present continuous threats. Quaternary bis-pyridinium aldoximes are potent, highly polar cholinesterase reactivators and the mos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::11e44ec204501f6a78b5cd3a71491501
https://doi.org/10.2174/1874104502015010017
https://doi.org/10.2174/1874104502015010017
Publikováno v:
Molecular and Cellular Biochemistry. 476:4301-4321
Allium species, belonging to Alliaceae family, are among the oldest cultivated vegetables used as food. Garlic, onions, leeks and chives, which belong to this family, have been reported to have medicinal properties. The Allium species constituents ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3fb749998895c29e94534c224bd44437
https://doi.org/10.1007/s11010-021-04213-2
https://doi.org/10.1007/s11010-021-04213-2
Publikováno v:
Acta Chromatographica. 33:134-144
Mono- and bis-pyridinium quaternary aldoximes (K-oximes) have long been employed as cholinesterase reactivator components of antidotes against lethal cholinesterase-inhibiting organophosphorous chemicals. Their positive charge poses difficulties in t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::58e1df246e5e97f7dc91f064c5070bad
https://doi.org/10.1556/1326.2020.00781
https://doi.org/10.1556/1326.2020.00781
Autor:
Mohamed Omer Mahgoub, Ifrah Ismail Ali, Jennifer O. Adeghate, Kornélia Tekes, Huba Kalász, Ernest A. Adeghate
Publikováno v:
International Journal of Molecular Sciences. 24:9328
Diabetes mellitus (DM) is a chronic illness with an increasing global prevalence. More than 537 million cases of diabetes were reported worldwide in 2021, and the number is steadily increasing. The worldwide number of people suffering from DM is proj
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c778a78eb4e19e3300d04465f76b55da
https://doi.org/10.3390/ijms24119328
https://doi.org/10.3390/ijms24119328
Autor:
Kamil Kuca, Gellért Karvaly, Márton Milánkovits, Jennifer Adeghate, Kornélia Tekes, Ferenc Darvas, Kamil Musilek, Ferenc Szimrók, Huba Kalász, Dóra Szabó, András Keglevich
Publikováno v:
The Open Medicinal Chemistry Journal. 14:99-107
Background: Our recent work has been treating the pharmacokinetics of pyridinium aldoximes of various structures including their time-dependent distribution in the body of male rats and also the extent of blood-brain-barrier penetration. Objective: O
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1a0177bc840b060cebb1491fed5776f9
https://doi.org/10.2174/1874104502014010099
https://doi.org/10.2174/1874104502014010099
Autor:
Ali Yahya, Ernest A. Adeghate, Ernest Adeghate, Faisal Adi, Sahar Mohsin, Kornélia Tekes, Huba Kalász, Fares Ahmed
Publikováno v:
Expert Opinion on Investigational Drugs. 28:811-820
Introduction: More than 424 million adults have diabetes mellitus (DM). This number is expected to increase to 626 million by 2045. The majority (90-95%) of people with DM has type 2-diabetes (T2DM). The continued prevalence of DM and associated comp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dc4d5f4942bc5eb8abad5de97004c02
https://doi.org/10.1080/13543784.2019.1655539
https://doi.org/10.1080/13543784.2019.1655539
Autor:
Ernest Adeghate, Kornélia Tekes, Huba Kalász, Jung Young-Sik, Barbara Malawska, Kamil Musilek, Gellért Karvaly, Syed M. Nurulain, Kamil Kuca, Tibor Zelles, Judit Szepesy
Publikováno v:
The Open Medicinal Chemistry Journal. 13:1-6
Background: Bis-pyridinium aldoximes are reactivators of the paraoxon-inhibited butyrylcholinesterase enzyme. Paraoxon is the active product of parathion, a widely used insecticide. Objective: The objective of this study is to examine the dose-depend
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f4b534618a468fac03e36b5bb71654f4
https://doi.org/10.2174/1874104501913010001
https://doi.org/10.2174/1874104501913010001