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Akademický článek

NSGA-II Genetic Algorithm Combined with Response Surface Methodology to Optimize the Extraction Process of Active Ingredients of Inonotus obliquus

Autor: Haocheng YUN, Fanhua YU, Du CHENG, Zhen LIU, Huazhou NIU, Wanchao HOU, Sainan LI, Chunming LIU, Yuchi ZHANG

Publikováno v: Shipin gongye ke-ji, Vol 43, Iss 17, Pp 185-193 (2022)

This paper aimed to investigate the extraction process of total flavonoids and triterpenes in Inonotus obliquus by ultrasound-assisted enzymatic extraction. The UV spectrophotometric method was used as the detection method, the extraction rate of tot

Externí odkaz: https://doaj.org/article/b378a853f7714a32969203385c4ff501

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Akademický článek

UHPLC-MS-Based Metabolomics Reveal the Potential Mechanism of Armillaria mellea Acid Polysaccharide in and Its Effects on Cyclophosphamide-Induced Immunosuppressed Mice

Autor: Ying Li, Qingqing Li, Huazhou Niu, Hui Li, Lili Jiao, Wei Wu

Publikováno v: Molecules, Vol 28, Iss 24, p 7944 (2023)

Armillaria mellea (Vahl) P. Kumm is commonly used for food and pharmaceutical supplements due to its immune regulatory function, and polysaccharides are one of its main components. The aim of this research is to study the immunological activity of th

Externí odkaz: https://doaj.org/article/0a3c480525024f39aadde6c812bc3334

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Akademický článek

Active Compounds of Panax ginseng in the Improvement of Alzheimer’s Disease and Application of Spatial Metabolomics

Autor: Meng Zhang, Huazhou Niu, Qingqing Li, Lili Jiao, Hui Li, Wei Wu

Publikováno v: Pharmaceuticals, Vol 17, Iss 1, p 38 (2023)

Panax ginseng C.A. Meyer (P. ginseng) is one of the more common traditional Chinese medicines (TCMs). It contains numerous chemical components and exhibits a range of pharmacological effects. An enormous burden is placed on people’s health and life

Externí odkaz: https://doaj.org/article/80aa19498f5f4cde8c597dcd17ddb962

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Akademický článek

Structure Elucidation and Immunoactivity Study of Armillaria mellea Fruiting Body Polysaccharides

Autor: Qingqing Li, Ying Li, Huazhou Niu, Enhui Wang, Lili Jiao, Hui Li, Wei Wu

Publikováno v: Separations, Vol 11, Iss 1, p 3 (2023)

Polysaccharides are the main nutritional constituents in the Armillaria mellea fruiting bodies. The structure and immunoactivity of Armillaria mellea polysaccharide are valuable to be determined for development. In the present study, two polysacchari

Externí odkaz: https://doaj.org/article/d63f84f650ee44f0860b8f2cf85fe6db

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An efficient strategy based on two‐stage chromatography and in vitro evaluation for rapid screening and isolation of acetylcholinesterase inhibitors from Scutellaria baicalensis Georgi

Autor: Wanchao Hou, Chunming Liu, Sainan Li, Yuchi Zhang, Yongri Jin, Xuwen Li, Zhen Liu, Huazhou Niu, Jianli Xia

Publikováno v: Journal of Separation Science. 45:1170-1184

The extraction of Scutellaria baicalensis Georgi was investigated using the response surface methodology-genetic algorithm mathematical regression model, and the extraction variables were optimized to maximize the flavonoid yield. Furthermore, a simp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d50d0f2c91798c0ce919ba656d84b06
https://doi.org/10.1002/jssc.202100918

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Ionic‐liquid‐based ultrasound‐assisted extraction combined with countercurrent chromatography and semipreparative LC for the preparation of monoamine oxidase B inhibitors from Pueraria thomsonii

Autor: Sainan Li, Yanjie Li, Ying Wang, Ruizhe Li, Huazhou Niu, Chunming Liu, Yuchi Zhang

Publikováno v: Journal of Separation Science. 45:1116-1127

A simple and efficient method was developed for the rapid screening and identification of ligands for monoamine oxidase B. A new ionic-liquid-based ultrasound-assisted extraction method for medicinal herbs was also developed and validated. In additio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abd49bc45728de57281e1dcef5fb1f39
https://doi.org/10.1002/jssc.202100799

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Development of a method to screen and isolate xanthine oxidase inhibitors from black bean in a single step: Hyphenation of semipreparative liquid chromatography and stepwise flow rate countercurrent chromatography

Autor: Wanchao Hou, Zhen Liu, Yuchi Zhang, Sainan Li, Chunming Liu, Huazhou Niu, Hao-cheng Yun

Publikováno v: Journal of Separation Science. 45:492-506

Black bean, in which isoflavones are the main active constituent, also contains saponins, and monoterpenes. Soybean isoflavone is a secondary metabolite that is formed during the growth of soybean; it exhibits antioxidant and cardiovascular activitie

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::217b64af981c3e5d95b3da51d7861ee0
https://doi.org/10.1002/jssc.202100663

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Screening and isolation of potential lipoxidase and superoxide dismutase inhibitors from Scutellaria baicalensis Georgi using high-speed countercurrent chromatography target-guided by ultrafiltration-liquid chromatography-mass spectrometry

Autor: Huazhou Niu, Jianli Xia, Wanchao Hou, Sainan Li, Chunming Liu

Publikováno v: Journal of separation scienceREFERENCES. 44(7)

We present a simple and efficient method based on ultrafiltration high-performance liquid chromatography coupled with a photodiode array detector and electrospray ionisation mass spectrometry for the rapid screening and identification of ligands obta

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3220c0eb1fcdeefcfb4a6204c0ec877
https://pubmed.ncbi.nlm.nih.gov/33433962

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