Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Huazhang Zhu"'
Autor:
Huazhang Zhu, Dawei Wang, Zuodong Ye, Lihong Huang, Wenjie Wei, Kui Ming Chan, Rongxin Zhang, Liang Zhang, Jianbo Yue
Publikováno v:
BMC Biology, Vol 22, Iss 1, Pp 1-15 (2024)
Abstract Background Many viruses enter host cells by hijacking endosomal trafficking. CapZ, a canonical actin capping protein, participates in endosomal trafficking, yet its precise role in endocytosis and virus infection remains elusive. Results Her
Externí odkaz:
https://doaj.org/article/8e664f916c61404889caad51f17ef210
Autor:
Huazhang Zhu, Weizhen Zhang, Yingying Zhao, Xingsheng Shu, Wencong Wang, Dandan Wang, Yangfan Yang, Zhijun He, Xiaomei Wang, Ying Ying
Publikováno v:
Molecular Neurodegeneration, Vol 13, Iss 1, Pp 1-17 (2018)
Abstract Background Although diabetic retinopathy (DR) has long been considered as a microvascular disorder, mounting evidence suggests that diabetic retinal neurodegeneration, in particular synaptic loss and dysfunction of retinal ganglion cells (RG
Externí odkaz:
https://doaj.org/article/aac18fd2322c401fa9ff04bd8b07ec7d
Autor:
Youli Yao, Ying Ying, Qiyu Deng, Wenjiang Zhang, Huazhang Zhu, Zhenglong Lin, Shengli Zhang, Junxian Ma, Yingying Zhao
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
Alzheimer’s disease (AD) patients often exhibit perturbed circadian rhythm with fragmented sleep before disease onset. This study was designed to evaluate the effect of a 40-Hz light flicker on circadian rhythm in an AD mouse model (APP/PS1). Locom
Externí odkaz:
https://doaj.org/article/6c61ac73cf064978a8be73335fc92fcc
Autor:
Zhijun He, Shuangxue Han, Huazhang Zhu, Xia Hu, Xiaoqian Li, Chaofan Hou, Chong Wu, Qingguo Xie, Nan Li, Xiubo Du, Jiazuan Ni, Qiong Liu
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 13 (2020)
Alzheimer’s disease (AD) is a widely distributed neurodegenerative disease characterized clinically by cognitive deficits and pathologically by formation of amyloid-β (Aβ) plaque and neurofibrillary tangles (NFTs) in the brain. Vanadium is a biol
Externí odkaz:
https://doaj.org/article/dc737b0862384e938737f261ca0ce92b
Autor:
Zhijun He, Wen Xiao, Nan Li, Jianxi Song, Chong Wu, Xiubo Du, Xiaoqian Li, Jiazuan Ni, Xuexia Li, Huazhang Zhu, Qiong Liu
Publikováno v:
JBIC Journal of Biological Inorganic Chemistry. 26:551-568
Endoplasmic reticulum stress (ER stress) plays a critical role in neuronal apoptosis along with the aggravation of Alzheimer's disease (AD). Nuclear receptor peroxisome proliferator-activated receptor gamma (PPARγ) is a ligand-activated transcriptio
Autor:
Huazhang Zhu, Yangfan Yang, Minbin Yu, Sarah X. Zhang, Ying Ying, Hui Xiao, Jingming Li, Xing Liu, Yiming Ye, Yimin Zhong, Ran Xue, Guo Chen
Publikováno v:
Aging (Albany NY)
Primary open angle glaucoma (POAG) is the leading cause of irreversible blindness. Dysfunction of the trabecular meshwork (TM), resulting in decreased outflow of aqueous humor and increased intraocular pressure (IOP), plays an important role in the p
Autor:
Le Cheng, Xianxiong Chen, Yingying Zhao, Yiming Ye, Junxian Ma, Yatao Yang, Yixiang Zhang, Xingsheng Shu, Yangfan Yang, Huazhang Zhu, Ying Ying, Xiaoyan Huang, Youli Yao, Xiaomei Wang
Publikováno v:
Journal of Cellular and Molecular Medicine
Primary open‐angle glaucoma (POAG) is the second leading cause of irreversible blindness worldwide. Increased endothelin‐1 (ET‐1) has been observed in aqueous humour (AH) of POAG patients, resulting in an increase in the out‐flow resistance o
Autor:
Lina Liu, Xiubo Du, Zhijun He, Lu Wan, Xiao-Gai Yang, Qingguo Xie, Nan Li, Lu Qiying, Huazhang Zhu, Ang Liu, Shuangxue Han, Qiong Liu, Jiazuan Ni, Chong Wu, Huang Jingqiang, Lingling Chen
Publikováno v:
Metallomics. 12:474-490
Vanadium compounds have been reported to mimic the anti-diabetes effects of insulin on rodent models, but their effects on Alzheimer’s disease (AD) have rarely been explored. In this paper, 9-month-old triple transgenic AD model mice (3×Tg-AD) rec
Autor:
Renkun Chen, Yanliang Zhang, Qingfeng Xing, Yue Wu, Thomas C. Chasapis, Nicholas Kempf, Zhe Li, Shuang Cui, G. Jeffrey Snyder, Huazhang Zhu, Enzheng Shi, Je-Hyeong Bahk
Publikováno v:
Nano Research. 13:1339-1346
Anisotropy and inhomogeneity are ubiquitous in spark plasma sintered thermoelectric devices. However, the origin of inhomogeneity in thermoelectric nanocomposites has rarely been investigated so far. Herein, we systematically study the impact of inho
Autor:
Kaiyuan Zhu, Yang Cai, Xiaotong Si, Zuodong Ye, Yuanzhu Gao, Chuang Liu, Rui Wang, Zhibin Ma, Huazhang Zhu, Liang Zhang, Shengjin Li, Hongmin Zhang, Jianbo Yue
Publikováno v:
Cell death and differentiation. 29(10)
The proper orientation of centrosome and spindle is essential for genome stability; however, the mechanism that governs these processes remains elusive. Here, we demonstrated that polo-like kinase 1 (Plk1), a key mitotic kinase, phosphorylates residu