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Akademický článek

Tumor-Specific CD4+ T Cells Restrain Established Metastatic Melanoma by Developing Into Cytotoxic CD4– T Cells

Autor: Qiao Liu, Lisha Wang, Huayu Lin, Zhiming Wang, Jialin Wu, Junyi Guo, Shuqiong Wen, Ling Ran, Zhengliang Yue, Xingxing Su, Qing Wu, Jianfang Tang, Zhirong Li, Li Hu, Lifan Xu, Lilin Ye, Qizhao Huang

Publikováno v: Frontiers in Immunology, Vol 13 (2022)

Cytotoxic CD8+ T cells are the main focus of efforts to understand anti-tumor immunity and immunotherapy. The adoptive transfer of tumor-reactive cytotoxic CD8+ T lymphocytes expanded and differentiated in vitro has long been considered the primary s

Externí odkaz: https://doaj.org/article/5ff83e5054d4437889eaa6d509215c76

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Akademický článek

Bcl6 Preserves the Suppressive Function of Regulatory T Cells During Tumorigenesis

Autor: Yiding Li, Zhiming Wang, Huayu Lin, Lisha Wang, Xiangyu Chen, Qiao Liu, Qianfei Zuo, Jianjun Hu, Haoqiang Wang, Junyi Guo, Luoyingzi Xie, Jianfang Tang, Zhirong Li, Li Hu, Litian Xu, Xinyuan Zhou, Lilin Ye, Qizhao Huang, Lifan Xu

Publikováno v: Frontiers in Immunology, Vol 11 (2020)

During tumorigenesis, tumor infiltrating regulatory T (Treg) cells restrict the function of effector T cells in tumor microenvironment and thereby promoting tumor growth. The anti-tumor activity of effector T cells can be therapeutically unleashed, a

Externí odkaz: https://doaj.org/article/2646097ec8d24696adbdde1672fd045f

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Tumor Transplantation for Assessing the Dynamics of Tumor-Infiltrating CD8+ T Cells in Mice

Autor: Lisha, Wang, Zhiming, Wang, Junyi, Guo, Huayu, Lin, Shuqiong, Wen, Qiao, Liu, Yiding, Li, Qing, Wu, Leiqiong, Gao, Xiangyu, Chen, Luoyingzi, Xie, Qin, Tian, Jianfang, Tang, Zhirong, Li, Li, Hu, Juan, Wang, Lifan, Xu, Qizhao, Huang, Lilin, Ye

Publikováno v: Journal of visualized experiments : JoVE. (172)

T cell-mediated immunity plays a crucial role in immune responses against tumors, with cytotoxic T lymphocytes (CTLs) playing the leading role in eradicating cancerous cells. However, the origins and replenishment of tumor antigen-specific CD8

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::88ce611bdb560921a2c423680aedf465
https://pubmed.ncbi.nlm.nih.gov/35485914

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Tumor Transplantation for Assessing the Dynamics of Tumor-Infiltrating CD8+ T Cells in Mice

Autor: Luoyingzi Xie, Zhirong Li, Lifan Xu, Lilin Ye, Xiangyu Chen, Qizhao Huang, Leiqiong Gao, Qiao Liu, Qing Wu, Qin Tian, Shuqiong Wen, Junyi Guo, Yiding Li, Zhiming Wang, Li Hu, Jianfang Tang, Lisha Wang, Huayu Lin, Juan Wang

Publikováno v: Journal of Visualized Experiments.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6dccdc23c3101d04c9d55728533f13d
https://doi.org/10.3791/62442

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A novel strategy to investigate the factors regulating the Treg to Tfr transition during acute viral infection

Autor: Huayu Lin, Haoqiang Wang, Qiao Liu, Zhiming Wang, Shuqiong Wen, Lisha Wang, Junyi Guo, Ling Ran, Zhengliang Yue, Qing Wu, Jianfang Tang, Zhirong Li, Li Hu, Lifan Xu, Qizhao Huang, Lilin Ye

Publikováno v: Journal of Immunological Methods. 505:113266

Follicular regulatory T cells (Tfrs), a specialized subset of regulatory T cells (Tregs), have a particular role in the control of follicular helper T cell-driven germinal center (GC) responses. Following differentiation signals similar to those rece

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d1ca0c372b8d1f48c6241fb30dc5d02
https://doi.org/10.1016/j.jim.2022.113266

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