Zobrazeno 1 - 10
of 84
pro vyhledávání: '"Huaye Zhang"'
Autor:
Mikayla M. Voglewede, Elif Naz Ozsen, Noah Ivak, Matteo Bernabucci, Ruizhe Tang, Miao Sun, Zhiping P. Pang, Huaye Zhang
Publikováno v:
iScience, Vol 27, Iss 7, Pp 110308- (2024)
Summary: The Par3 polarity protein is critical for subcellular compartmentalization in different developmental processes. Variants of PARD3, encoding PAR3, are associated with intelligence and neurodevelopmental disorders. However, the role of Par3 i
Externí odkaz:
https://doaj.org/article/45b2d2f255fb4010a9a02d8aeeb8edb8
Autor:
Tatiana Popovitchenko, Yongkyu Park, Nicholas F. Page, Xiaobing Luo, Zeljka Krsnik, Yuan Liu, Iva Salamon, Jessica D. Stephenson, Matthew L. Kraushar, Nicole L. Volk, Sejal M. Patel, H. R. Sagara Wijeratne, Diana Li, Kandarp S. Suthar, Aaron Wach, Miao Sun, Sebastian J. Arnold, Wado Akamatsu, Hideyuki Okano, Luc Paillard, Huaye Zhang, Steven Buyske, Ivica Kostovic, Silvia De Rubeis, Ronald P. Hart, Mladen-Roko Rasin
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-21 (2020)
Translational regulation of isoforms in the developing nervous system is not well understood. Here, the authors report translational de-repression of RNA binding protein isoforms at their 5′UTRs in the neocortex and show the neurodevelopmental risk
Externí odkaz:
https://doaj.org/article/26ec0393d8414ff985171a47ea4a1728
Autor:
Yingying Liu, Samantha Gokhale, Jaeyong Jung, Sining Zhu, Chang Luo, Debanjan Saha, Jessie Yanxiang Guo, Huaye Zhang, Saw Kyin, Wei-Xing Zong, Eileen White, Ping Xie
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Proteins controlling mitochondrial fission have been recognized as essential regulators of mitochondrial functions, mitochondrial quality control and cell apoptosis. In the present study, we identified the critical B cell survival regulator TRAF3 as
Externí odkaz:
https://doaj.org/article/7dbee4054d5a4b1598e411e3fdd1884f
Autor:
Victoria L. DiBona, Wenxin Zhu, Mihir K. Shah, Aditi Rafalia, Hajer Ben Cheikh, David P. Crockett, Huaye Zhang
Publikováno v:
Journal of Neuroinflammation, Vol 16, Iss 1, Pp 1-15 (2019)
Abstract Background Microglia, the resident immune cells of the brain, exhibit various morphologies that correlate with their functions under physiological and pathological conditions. In conditions such as aging and stress, microglia priming occurs,
Externí odkaz:
https://doaj.org/article/0fcdd4f0d131430a91b55f0ae151e50e
Publikováno v:
Neurobiology of Disease, Vol 93, Iss , Pp 1-11 (2016)
The processing of amyloid precursor protein (APP) into β-amyloid peptide (Aβ) is a key step in the pathogenesis of Alzheimer’s disease (AD), and trafficking dysregulations of APP and its secretases contribute significantly to altered APP processi
Externí odkaz:
https://doaj.org/article/2fe6d6b60884479a958d8abe39fbefcc
Autor:
Huaye Zhang
Publikováno v:
Neural Plasticity, Vol 2016 (2016)
The asymmetric distribution of various proteins and RNAs is essential for all stages of animal development, and establishment and maintenance of this cellular polarity are regulated by a group of conserved polarity determinants. Studies over the last
Externí odkaz:
https://doaj.org/article/660674c24db04a1e880de814ec4b6ad5
Autor:
Laura P Bernard, Huaye Zhang
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0124816 (2015)
The Par1 kinases, also known as microtubule affinity-regulating kinases (MARKs), are important for the establishment of cell polarity from worms to mammals. Dysregulation of these kinases has been implicated in autism, Alzheimer's disease and cancer.
Externí odkaz:
https://doaj.org/article/0159f13ea4d64e40a2ae2fb15cae89a9
Autor:
Mikayla M. Voglewede, Huaye Zhang
Publikováno v:
Developmental Biology. 488:68-73
The morphogenesis and plasticity of dendritic spines are associated with synaptic strength, learning, and memory. Dendritic spines are highly compartmentalized structures, which makes proteins involved in cellular polarization and membrane compartmen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a43d179f12ac82344eac51f20405ac69
https://doi.org/10.1016/j.ydbio.2022.05.007
https://doi.org/10.1016/j.ydbio.2022.05.007
Autor:
Dana M. Smith, Victoria L. DiBona, David P. Crockett, Huaye Zhang, Mikayla M. Voglewede, Kayla J. Krause, Wenxin Zhu, Mihir Shah
Publikováno v:
Neurosci Res
Within the brain, traumatic brain injury (TBI) alters synaptic plasticity and increases neuroinflammation and neuronal death. Yet, there lacks effective TBI treatments providing pleiotropic beneficial effects on these diverse cellular processes neces
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::040cee63e8b8810d85acf6f70737dd07
https://doi.org/10.1016/j.neures.2021.05.007
https://doi.org/10.1016/j.neures.2021.05.007
Publikováno v:
Biochemical and Biophysical Research Communications. 632:206-207
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::08c8b6261f0454f1170053cc7a849130
https://doi.org/10.1016/j.bbrc.2022.10.012
https://doi.org/10.1016/j.bbrc.2022.10.012