Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Huaxing Shen"'
Autor:
Wei Cong, Huaxing Shen, Xiufei Liao, Mengjun Zheng, Xianglong Kong, Zhe Wang, Si Chen, Yulei Li, Honggang Hu, Xiang Li
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 13, Iss 9, Pp 3770-3781 (2023)
Stapled peptides with significantly enhanced pharmacological profiles have emerged as promising therapeutic molecules due to their remarkable resistance to proteolysis and performance to penetrate cells. The all-hydrocarbon peptide stapling technique
Externí odkaz:
https://doaj.org/article/7a71b664e86b4b37991939924003c6ef
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
Wnt signaling plays an important role in many biological processes such as stem cell self-renewal, cell proliferation, migration, and differentiation. The β-catenin-dependent signaling pathway mainly regulates cell proliferation, differentiation, an
Externí odkaz:
https://doaj.org/article/eebcf0a23d624eedbaf536cd3edee809
Autor:
Si Chen, Chenchen Geng, Mengjun Zheng, Jie Qing, Wei-Dong Zhang, Yaxin Tang, Yan Zou, Huaxing Shen, Haoran Peng, Xiang Li, Honggang Hu, Wei Cong
Publikováno v:
Journal of Medicinal Chemistry. 64:17486-17495
The pandemic of acute respiratory disease in 2019 caused by highly pathogenic and infectious SARS-CoV-2 has seriously endangered human public safety. The 6-HB (HR1-HR2 complex) formation occurring in the process of spike protein-mediated membrane fus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01ab4456dcd8c7f8f414877180b57e5a
https://doi.org/10.1021/acs.jmedchem.1c01681
https://doi.org/10.1021/acs.jmedchem.1c01681
Publikováno v:
American journal of translational research. 14(11)
Liver cancer stem cells (LCSCs) are regarded as the frequent cause of hepatocellular carcinoma (HCC) relapse and therapeutic resistance. The epithelial cell adhesion molecule (EpCAM) is one of the key biomarkers for LCSCs. EpCAMEpCAMMASM significantl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5563752b4258f55f284902e1fdcce0a6
https://pubmed.ncbi.nlm.nih.gov/36505290
https://pubmed.ncbi.nlm.nih.gov/36505290
Autor:
Liying Pang, Hong Jin, Zhengmao Lu, Fangyuan Xie, Huaxing Shen, Xinying Li, Xinyi Zhang, Xianghe Jiang, Lili Wu, Mengya Zhang, Tinglin Zhang, Yonghua Zhai, Yuanyuan Zhang, Huilin Guan, Jiacan Su, Meng Li, Jie Gao
Publikováno v:
Advanced Healthcare Materials. :2300315
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9a9e4c00c3025d918d9f20542f5129e0
https://doi.org/10.1002/adhm.202300315
https://doi.org/10.1002/adhm.202300315
Autor:
Xiaoyuan Zhao, Xiang Li, Bo Li, Yao Sun, Yejiao Shi, Huaxing Shen, Fan Wang, Jingjing Li, Farukh Sharopov, Zainiddin Mukhiddinov, Chao Ma, Kai Liu, Hong-Gang Hu
Publikováno v:
Chemical Engineering Journal. 453:139886
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2ef5b609348ca84489da81ea0458c5fe
https://doi.org/10.1016/j.cej.2022.139886
https://doi.org/10.1016/j.cej.2022.139886
Autor:
Guanfeng Yao, Huaxing Shen, Zhen Lian, Gang Xie, Jican Zeng, Wei Cong, Zihong Lin, Jiajie Ye, Wenjie Liu, Haotian Feng, Xinjia Wang, Guixin Yuan, Dantao Xie, Weidong Wang
Publikováno v:
Biochemical Pharmacology. 188:114579
Osteolytic diseases, including breast cancer-induced osteolysis and postmenopausal osteoporosis, are attributed to excessive bone resorption by osteoclasts. Spleen tyrosine kinase (SYK) is involved in osteoclastogenesis and bone resorption, whose rol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f39c3df05ceb564c737c3e0c96166cd2
https://doi.org/10.1016/j.bcp.2021.114579
https://doi.org/10.1016/j.bcp.2021.114579
Autor:
Xiaosong Bai, Huaxing Shen, Liang Zhao, Nan Wang, Wei Cong, Shili Xiong, Honggang Hu, Lijun Zhu, Zengqiang Qu, Chao Liu
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 37:127831
Brevinin-1BYa is an amphibian skin-derived peptide that exhibits promising anti-microbial activity against gram-positive and -negative bacteria. However, the anti-tumor activity of Brevinin-1BYa remains unclear, and, more importantly, its therapeutic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e40f5b890ee74a6e4aeac64a06260a5
https://doi.org/10.1016/j.bmcl.2021.127831
https://doi.org/10.1016/j.bmcl.2021.127831