Zobrazeno 1 - 10
of 275
pro vyhledávání: '"Huaxin Sheng"'
Autor:
Ángela del Águila, Ran Zhang, Xinyuan Yu, Lihong Dang, Feng Xu, Jin Zhang, Vaibhav Jain, Jilin Tian, Xiao-Ping Zhong, Huaxin Sheng, Wei Yang
Publikováno v:
Genome Medicine, Vol 16, Iss 1, Pp 1-21 (2024)
Abstract Background Ischemic stroke elicits a complex and sustained immune response in the brain. Immunomodulatory treatments have long held promise for improving stroke outcomes, yet none have succeeded in the clinical setting. This lack of success
Externí odkaz:
https://doaj.org/article/848dab080e1b4085bd4aa81a6c92e9c9
Autor:
Wenxu Zhang, Yajuan Li, Anthony A. Fung, Zhi Li, Hongje Jang, Honghao Zha, Xiaoping Chen, Fangyuan Gao, Jane Y. Wu, Huaxin Sheng, Junjie Yao, Dorota Skowronska-Krawczyk, Sanjay Jain, Lingyan Shi
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Lipids play crucial roles in many biological processes. Mapping spatial distributions and examining the metabolic dynamics of different lipid subtypes in cells and tissues are critical to better understanding their roles in aging and disease
Externí odkaz:
https://doaj.org/article/e4d19d2cd7ce42d29dc0d13cf5953525
Autor:
Xiaoyi Zhu, Qiang Huang, Anthony DiSpirito, Tri Vu, Qiangzhou Rong, Xiaorui Peng, Huaxin Sheng, Xiling Shen, Qifa Zhou, Laiming Jiang, Ulrike Hoffmann, Junjie Yao
Publikováno v:
Light: Science & Applications, Vol 11, Iss 1, Pp 1-15 (2022)
The ultrafast wide-field photoacoustic microscopy integrates novel light source, fast scanning mechanism, and machine learning enhancement, which allows high-speed tracking of whole-brain functions in action at capillary level.
Externí odkaz:
https://doaj.org/article/699a4dcc99ff4e6398ef8707a9ad8d5a
Autor:
Xuan Li, Jingjun Lyu, Ran Li, Vaibhav Jain, Yuntian Shen, Ángela del Águila, Ulrike Hoffmann, Huaxin Sheng, Wei Yang
Publikováno v:
Journal of Neuroinflammation, Vol 19, Iss 1, Pp 1-8 (2022)
Abstract Background Ischemic stroke is a medical emergency that primarily affects the elderly. A complex immune response in the post-stroke brain constitutes a key component of stroke pathophysiology. This study aimed to determine how stroke affects
Externí odkaz:
https://doaj.org/article/43d798b4ba404a69ae64ce3d4a6d98e1
Autor:
Xuan Li, Weina Duan, Li Du, Dongmei Chu, Peng Wang, Zhong Yang, Xingguang Qu, Zhenxing Yang, Ines Batinic-Haberle, Ivan Spasojevic, David S. Warner, James D. Crapo, Miriam M. Treggiari, Huaxin Sheng
Publikováno v:
Antioxidants, Vol 12, Iss 10, p 1861 (2023)
Endovascular mechanical thrombectomy, combined with a tissue plasminogen activator (t-PA), is efficacious as a standard care for qualifying ischemic stroke patients. However, > 50% of thrombectomy patients still have poor outcomes. Manganese porphyri
Externí odkaz:
https://doaj.org/article/cd7bd498d53b459a86835b675ccfbd52
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 16 (2022)
Objective: Brain ischemia leads to the accumulation of unfolded/misfolded proteins in the endoplasmic reticulum (ER) lumen and consequently, ER stress. To help cells restore ER function, a series of adaptive stress response pathways, collectively ter
Externí odkaz:
https://doaj.org/article/b261a86dd9f9448e9d7b44ca8a6e5ba7
Autor:
Maorong Jiang, Ran Li, Jingjun Lyu, Xuan Li, Wei Wang, Zhuoran Wang, Huaxin Sheng, Weiguo Zhang, Jörn Karhausen, Wei Yang
Publikováno v:
Journal of Neuroinflammation, Vol 17, Iss 1, Pp 1-12 (2020)
Abstract Background Cardiac arrest (CA) is associated with high morbidity and mortality, even after spontaneous circulation is re-established. This dire situation is partly due to post-CA syndrome for which no specific and effective intervention is a
Externí odkaz:
https://doaj.org/article/6b94a45d2a344ca68fd2282e26383ff6
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 10, Iss 12 (2021)
Background Ischemia/reperfusion injury impairs proteostasis, and triggers adaptive cellular responses, such as the unfolded protein response (UPR), which functions to restore endoplasmic reticulum homeostasis. After cardiac arrest (CA) and resuscitat
Externí odkaz:
https://doaj.org/article/ac9cf197f74e4eb5a2cdabed4960d93b
Autor:
Wei Wang, Ran Li, Wanying Miao, Cody Evans, Liping Lu, Jingjun Lyu, Xuan Li, David S. Warner, Xiaoping Zhong, Ulrike Hoffmann, Huaxin Sheng, Wei Yang
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 10, Iss 11 (2021)
Background Animal disease models represent the cornerstone in basic cardiac arrest (CA) research. However, current experimental models of CA and resuscitation in mice are limited. In this study, we aimed to develop a mouse model of asphyxial CA follo
Externí odkaz:
https://doaj.org/article/e9649b049f5440bd9734e13b11d309c7
Autor:
Xiaonan Ma, Zihan Liao, Rongxuan Li, Wei Xia, Honghui Guo, Jiawei Luo, Huaxin Sheng, Meihui Tian, Zhipeng Cao
Publikováno v:
Molecules, Vol 27, Iss 13, p 4284 (2022)
Chronic alcohol exposure can cause myocardial degenerative diseases, manifested as cardiac insufficiency, arrhythmia, etc. These are defined as alcoholic cardiomyopathy (ACM). Alcohol-mediated myocardial injury has previously been studied through met
Externí odkaz:
https://doaj.org/article/278aed2aab684471bedc6b70dbac49a9