Zobrazeno 1 - 10
of 129
pro vyhledávání: '"Huawu Shao"'
Publikováno v:
Molecules, Vol 29, Iss 5, p 1179 (2024)
Inhibition of glycoside hydrolases has widespread application in the treatment of diabetes. Based on our previous findings, a series of dihydrofuro[3,2-b]piperidine derivatives was designed and synthesized from D- and L-arabinose. Compounds 32 (IC50
Externí odkaz:
https://doaj.org/article/9db0a682e8f24c189669acbabeed4e34
Publikováno v:
Molecules, Vol 28, Iss 19, p 6922 (2023)
Several monoterpene glycoside compounds were extracted from Paeonia lactiflora Pall. Among them, paeoniflorin, a water-soluble monoterpene glycoside found in the root of Paeonia lactiflora Pall, exhibits excellent antioxidant pharmacological function
Externí odkaz:
https://doaj.org/article/922f18722b794c5193ab1c5153f6a9fd
Publikováno v:
Molecules, Vol 28, Iss 3, p 923 (2023)
Dess–Martin periodinane (DMP) is a broadly applicable oxidant in chemical synthesis. In this work, an efficient and convenient synthesis of N-substituted isoquinolinone derivatives mediated by DMP was achieved through the oxidative coupling reactio
Externí odkaz:
https://doaj.org/article/a92ed1ac194f46508a5f6bfc840dca07
Publikováno v:
Molecules, Vol 27, Iss 23, p 8517 (2022)
Axially chiral heterobiaryl frameworks are privileged structures in many natural products, pharmaceutically active molecules, and chiral ligands. Therefore, a variety of approaches for constructing these skeletons have been developed. Among them, de
Externí odkaz:
https://doaj.org/article/9a8c5a17506d4516b3649e5dd725f6d7
Publikováno v:
Molecules, Vol 27, Iss 23, p 8538 (2022)
A new approach for the synthesis of 2-aminobenzofurans has been described via Sc(OTf)3 mediated formal cycloaddition of isocyanides with the in situ generated ortho-quinone methides (o-QMs) from o-hydroxybenzhydryl alcohol. Notably, as a class of rea
Externí odkaz:
https://doaj.org/article/9ee00a99a9a44d66af28d33956e94a6c
Publikováno v:
Molecules, Vol 27, Iss 17, p 5517 (2022)
A series of N-substituted iminosugar C-glycosides were synthesized and tested for α-glucosidase inhibition. The results suggested that 6e is a promising and potent α-glucosidase inhibitor. Enzymatic kinetic assays indicated that compound 6e may be
Externí odkaz:
https://doaj.org/article/0f0d867a5d4f46f2b9396023785253a4
Autor:
Yongqian Shu, Xue Wu, Xiaoling Tong, Xiaonan Wang, Zhili Chang, Yu Mao, Xiaofeng Chen, Jing Sun, Zhenxin Wang, Zhuan Hong, Liangjun Zhu, Chunrong Zhu, Jun Chen, Ying Liang, Huawu Shao, Yang W. Shao
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract Cancer is a disease of complex genetic alterations, and comprehensive genetic diagnosis is beneficial to match each patient to appropriate therapy. However, acquisition of representative tumor samples is invasive and sometimes impossible. Ci
Externí odkaz:
https://doaj.org/article/61fe10b0daf04456b58c5188a5068358
Publikováno v:
The Journal of Organic Chemistry. 87:16736-16742
Autor:
Xiaoke Zhang, Haibo Wang, Ziwei Li, Yan Shu, Song Gan, Xuefang Zhang, Huawu Shao, Chaoyong Wang
Publikováno v:
ACS Omega. 7:40963-40972
An efficient [4 + 1] annulation reaction between in situ generated azoalkene intermediates and α-bromocarbonyls has been established. A series of skeletally diverse aza-heterocycles with a functionalized quaternary center were obtained in up to 89%
Autor:
Mian Chen, Jiangjiang Zhang, Jie Qi, Ruihua Dong, Hongmei Liu, Decheng Wu, Huawu Shao, Xingyu Jiang
Publikováno v:
ACS Nano. 16:7732-7744
Metal-organic frameworks (MOFs) are promising photosensitized materials that have displayed great advantages in antibacterial application. However, their bactericidal activity is still limited by the ultrashort diffusion distance of biocidal reactive