Zobrazeno 1 - 10
of 202
pro vyhledávání: '"Huashan Liu"'
Autor:
Cuncan Deng, Mingyu Huo, Hongwu Chu, Xiaomei Zhuang, Guofei Deng, Wenchao Li, Hongfa Wei, Leli Zeng, Yulong He, Huashan Liu, Jia Li, Changhua Zhang, Hengxing Chen
Publikováno v:
Molecular Cancer, Vol 23, Iss 1, Pp 1-19 (2024)
Abstract Circular RNAs (circRNAs) play important roles in gastric cancer progression but the regulatory role of circRNAs in controlling macrophage function remains elusive. Exosomes serve as cargo for circRNAs and play a crucial role as mediators in
Externí odkaz:
https://doaj.org/article/a60329351d6b4968943c1feb15fe76b9
Autor:
Yebohao Zhou, Ziwei Zeng, Ze Li, Lei Ruan, Hao Xie, Fujin Ye, Liang Huang, Huashan Liu, Liang Kang
Publikováno v:
Therapeutic Advances in Gastroenterology, Vol 17 (2024)
Background: The significance of Kirsten rat sarcoma viral oncogene (KRAS) mutation in colorectal cancer (CRC) is well established; yet, its association with KRAS expression and prognosis warrants further investigation. While high KRAS expression is c
Externí odkaz:
https://doaj.org/article/4432dc77f62d43e9a72e63cd720666df
Autor:
Fujin Ye, Mian Chen, Xiaobin Zheng, Pinzhu Huang, Chao Wang, Huashan Liu, Hao Xie, Wei Xiao, Qin Guo, Liang Huang
Publikováno v:
BMC Gastroenterology, Vol 24, Iss 1, Pp 1-10 (2024)
Abstract Background Adenosquamous carcinoma is a rare sub-type of colorectal cancer with a poor prognosis. Little is known about its clinicopathological and molecular characteristics in Asian populations. This study aimed to investigate these feature
Externí odkaz:
https://doaj.org/article/76ec3ef052bb4126ba49d021bf53aabb
Autor:
Chi Zhou, Wenxin Li, Zhenxing Liang, Xianrui Wu, Sijing Cheng, Jianhong Peng, Kaixuan Zeng, Weihao Li, Ping Lan, Xin Yang, Li Xiong, Ziwei Zeng, Xiaobin Zheng, Liang Huang, Wenhua Fan, Zhanzhen Liu, Yue Xing, Liang Kang, Huashan Liu
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-21 (2024)
Abstract Mutant KRAS (KRASMUT) is often exploited by cancers to shape tumor immunity, but the underlying mechanisms are not fully understood. Here we report that tumor-specific cytotoxic T lymphocytes (CTLs) from KRASMUT cancers are sensitive to acti
Externí odkaz:
https://doaj.org/article/7cd3b6b5ef7b4ab08195a7dd2e90b3a8
Autor:
Li Xiong, Yingying Gong, Huashan Liu, Liang Huang, Ziwei Zeng, Xiaobin Zheng, Wenxin Li, Zhenxing Liang, Liang Kang
Publikováno v:
iScience, Vol 27, Iss 1, Pp 108680- (2024)
Summary: Circular RNAs (circRNAs) are crucial regulators of β-cell function and are involved in lipotoxicity-induced β-cell damage in type 2 diabetes mellitus (T2DM). We previously identified that circGlis3, a circRNA derived from exon 4 of the dia
Externí odkaz:
https://doaj.org/article/a3a78a43ce3d41eb9d68954ddd06ef02
Autor:
Wenfeng Liang, Haiqing Jie, Hao Xie, Yebohao Zhou, Wenxin Li, Liang Huang, Zhenxing Liang, Huashan Liu, Xiaobin Zheng, Ziwei Zeng, Liang Kang
Publikováno v:
Clinical & Translational Immunology, Vol 13, Iss 3, Pp n/a-n/a (2024)
Abstract Objectives Emerging evidence has demonstrated that tumour budding (TB) is negatively associated with T‐lymphocyte infiltration in CRC. Despite extensive research, the molecular characteristics of immunologically ‘hot’ TB remain poorly
Externí odkaz:
https://doaj.org/article/b99a3b9940924e6c8e8203c49b10fafa
Autor:
Chen Shen, Ilias Samathrakis, Kun Hu, Harish K. Singh, Nuno Fortunato, Huashan Liu, Oliver Gutfleisch, Hongbin Zhang
Publikováno v:
npj Computational Materials, Vol 8, Iss 1, Pp 1-12 (2022)
Abstract The Fe–Sn-based kagome compounds attract intensive attention due to its attractive topological transport and rich magnetic properties. Combining experimental data, first-principles calculations, and Calphad assessment, thermodynamic and to
Externí odkaz:
https://doaj.org/article/77e81d4eb26e49be916a361651230957
Publikováno v:
Journal of Materials Research and Technology, Vol 19, Iss , Pp 605-616 (2022)
The Au-28Ge (at%) eutectic alloy is a high-performance solder with a melting point of 361 °C. However, the brittle interfacial reaction products layer formed between the Au–Ge solder and substrate (Cu or Ni) is always the weak region. Hence, the j
Externí odkaz:
https://doaj.org/article/c2ee4974282a4131ab43db08bb2906ae
Autor:
Yihui Pan, Guannan Shu, Liangmin Fu, Kangbo Huang, Xinwei Zhou, Chengpeng Gui, Huashan Liu, Xiaohan Jin, Minyu Chen, Pengju Li, Junjie Cen, Zihao Feng, Jun Lu, Zhenhua Chen, Jiaying Li, Quanhui Xu, Yinghan Wang, Hui Liang, Zhu Wang, Qiong Deng, Wei Chen, Junhang Luo, Jiefeng Yang, Jiaxing Zhang, Jinhuan Wei
Publikováno v:
Advanced Science, Vol 10, Iss 11, Pp n/a-n/a (2023)
Abstract High lymphocyte infiltration and immunosuppression characterize the tumor microenvironment (TME) in renal cell carcinoma (RCC). There is an urgent need to elucidate how tumor cells escape the immune attack and to develop novel therapeutic ta
Externí odkaz:
https://doaj.org/article/61779df20f7547ad966d1eb6dbf1aeba
Autor:
Huashan Liu, Zhenxing Liang, Sijing Cheng, Liang Huang, Wenxin Li, Chi Zhou, Xiaobin Zheng, Shujuan Li, Ziwei Zeng, Liang Kang
Publikováno v:
Advanced Science, Vol 10, Iss 6, Pp n/a-n/a (2023)
Abstract The roles of oncogenic KRAS in tumor immune evasion remain poorly understood. Here, mutant KRAS is identified as a key driver of tumor immune evasion in colorectal cancer (CRC). In human CRC specimens, a significant reduction in cytotoxic CD
Externí odkaz:
https://doaj.org/article/3a6a099b6f4244b6a491a210edd9fb72