Zobrazeno 1 - 10
of 84
pro vyhledávání: '"Huarui Zhang"'
Autor:
Chuanxin Zhong, Nanxi Li, Shengzheng Wang, Dijie Li, Zhihua Yang, Lin Du, Guangxin Huang, Haitian Li, Wing Sze Yeung, Shan He, Shuting Ma, Zhuqian Wang, Hewen Jiang, Huarui Zhang, Zhanghao Li, Xiaoxin Wen, Song Xue, Xiaohui Tao, Haorui Li, Duoli Xie, Yihao Zhang, Zefeng Chen, Junqin Wang, Jianfeng Yan, Zhengming Liang, Zongkang Zhang, Zhigang Zhong, Zeting Wu, Chao Wan, Chao Liang, Luyao Wang, Sifan Yu, Yuan Ma, Yuanyuan Yu, Fangfei Li, Yang Chen, Baoting Zhang, Aiping Lyu, Fuzeng Ren, Hong Zhou, Jin Liu, Ge Zhang
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Excessive glucocorticoid (GC) action is linked to various metabolic disorders. Recent findings suggest that disrupting skeletal GC signaling prevents bone loss and alleviates metabolic disorders in high-fat diet (HFD)-fed obese mice, underpi
Externí odkaz:
https://doaj.org/article/4066e2b4eccd4e0695c1364b8d7b5dfd
Autor:
Tao Xiaohui, Luyao Wang, Xin Yang, Hewen Jiang, Ning Zhang, Huarui Zhang, Dijie Li, Xiaofei Li, Yihao Zhang, Shenghang Wang, Chuanxin Zhong, Sifan Yu, Meishen Ren, Meiheng Sun, Nanxi Li, Tienan Chen, Yuan Ma, Fangfei Li, Jin Liu, Yuanyuan Yu, Hua Yue, Zhenlin Zhang, Ge Zhang
Publikováno v:
Journal of Orthopaedic Translation, Vol 47, Iss , Pp 39-49 (2024)
Sclerostin emerges as a novel target for bone anabolic therapy in bone diseases. Osteogenesis imperfecta (OI) and X-linked hypophosphatemia (XLH) are rare bone diseases in which therapeutic potential of sclerostin inhibition cannot be ignored. In OI,
Externí odkaz:
https://doaj.org/article/af3deae3ca544e9785bfc76fae85e201
Autor:
Bowen Cheng, Huarui Zhang, Wenjin Zhao, Shaofeng Jiang, Zhijun Wu, Huiling Li, Shuai Liu, Hongshun Zhang
Publikováno v:
Heliyon, Vol 10, Iss 20, Pp e39620- (2024)
Background: Maduramicin (MAD) is an anticoccidial veterinary drug, but it frequently causes fatal poisonings in poultry, livestock, or humans. However, there is no specific antidote or guidance on first aid for MAD poisoning. Aim: The aim of the pres
Externí odkaz:
https://doaj.org/article/cca13c8c28d04706a0376529c84f38fd
Autor:
Amu Gubu, Yuan Ma, Sifan Yu, Huarui Zhang, Zefeng Chen, Shuaijian Ni, Razack Abdullah, Huan Xiao, Yihao Zhang, Hong Dai, Hang Luo, Yuanyuan Yu, Luyao Wang, Hewen Jiang, Ning Zhang, Yuan Tian, Haitian Li, Aiping Lu, Baoting Zhang, Ge Zhang
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 35, Iss 1, Pp 102146- (2024)
Osteogenesis imperfecta (OI) is a rare genetic disease characterized by bone fragility and bone formation. Sclerostin could negatively regulate bone formation by antagonizing the Wnt signal pathway, whereas it imposes severe cardiac ischemic events i
Externí odkaz:
https://doaj.org/article/b6892e8f6fee4f7bb088fbb3ea09388b
Autor:
Jinpeng Li, Huarui Zhang, Zhanxin Li, Ming Du, Jiulong Chen, Yesheng Xiong, Hu Zhang, Ying Cheng
Publikováno v:
Journal of Materials Research and Technology, Vol 26, Iss , Pp 7166-7181 (2023)
This study presents an innovative investigation into the wetting characteristic and flow behavior of sand particles, which have different shapes, sizes, and textures, when they bonded with silicate binder. The results revealed that the apparent conta
Externí odkaz:
https://doaj.org/article/4421c3ff7f4e47068acb131041f4de7c
Publikováno v:
Journal of Materials Research and Technology, Vol 26, Iss , Pp 3353-3367 (2023)
Microalloying is a cost-effective strategy to develop high performance nickel-based superalloys. Here, the mechanisms of rare earth Y in IN713C on purification, mechanical property improvement, and microstructure modification were systematically inve
Externí odkaz:
https://doaj.org/article/bc024a69157144b7b8e0b2642e5c18a0
Publikováno v:
International Journal of Disaster Risk Science, Vol 14, Iss 4, Pp 539-548 (2023)
Abstract Thaw slumping is a periglacial process that occurs on slopes in cold environments, where the ground becomes unstable and the surface slides downhill due to saturation with water during thawing. In this study, GaoFen-1 remote sensing and fuse
Externí odkaz:
https://doaj.org/article/effd1c2c18704696acb130df507272d1
Autor:
Jiangyan Jin, Yunlin Tang, Lu Cao, Xue Wang, Yebo Chen, Guozhen An, Huarui Zhang, Guoqing Pan, Jialing Bao, Zeyang Zhou
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 2 (2024)
ABSTRACTMicrosporidia are intracellular fungus-like pathogens and the infection symptoms include recurrent diarrhea and systematic inflammations. The major infection route of microsporidia is the digestive tract. Since microsporidia are hard to fully
Externí odkaz:
https://doaj.org/article/1d1770c0f80f4fc795c5a2cb861fce28
Autor:
Huarui Zhang, Huijuan Zhao, Lu Cao, Bin Yu, Junhong Wei, Guoqing Pan, Jialing Bao, Zeyang Zhou
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 1 (2024)
ABSTRACT Nosema bombycis is transmitted horizontally and vertically from infected female moths to progeny eggs, bringing substantial economic losses to sericulture production. Timely and accurate detection of N. bombycis can effectively block the spr
Externí odkaz:
https://doaj.org/article/49276523dd544875a4bc8c52a78407f2
Autor:
Huarui Zhang, Sifan Yu, Shuaijian Ni, Amu Gubu, Yuan Ma, Yihao Zhang, Haitian Li, Yuzhe Wang, Luyao Wang, Zongkang Zhang, Yuanyuan Yu, Aiping Lyu, Baoting Zhang, Ge Zhang
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 34, Iss , Pp 102073- (2023)
The molecular weight of nucleic acid aptamers (20 kDa) is lower than the cutoff threshold of the renal filtration (30–50 kDa), resulting in a very short half-life, which dramatically limits their druggability. To address this, we utilized 3-(2,5-di
Externí odkaz:
https://doaj.org/article/9411b16d164745c69a52c4f392875295