Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Huaqing Cui"'
Publikováno v:
Frontiers in Chemistry, Vol 9 (2021)
In this study, we evaluated the applicability of various superoxide anion sensors which were designed based on either redox or non-redox mechanisms. Firstly, both redox- and non–redox-based superoxide anion probes were designed and synthesized usin
Externí odkaz:
https://doaj.org/article/3b191ad2a0a846fdb014bcf2bf9c7323
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
Current methods used to evaluate in vivo target efficacy of selected compound include western blot to semi-quantitatively analyze protein expression. However, problems arise as it is difficult to compare in vivo target efficacy of anti-tumor agents w
Externí odkaz:
https://doaj.org/article/c214e77fb0384db98ed1638d212579ff
Autor:
Hui Wen, Yuke Liu, Shufang Wang, Ting Wang, Gang Zhang, Xiaoguang Chen, Yan Li, Huaqing Cui, Fangfang Lai, Li Sheng
Publikováno v:
Molecules, Vol 24, Iss 11, p 2124 (2019)
Indoleamine 2,3-dioxygenase (IDO) 1 is the key enzyme for regulating tryptophan metabolism and is an important target for interrupting tumor immune escape. In this study, we designed four series of compounds as potential IDO1 inhibitors by attaching
Externí odkaz:
https://doaj.org/article/0ec78bd81b724ba983ce7986ed50ff99
Publikováno v:
Molecules, Vol 23, Iss 5, p 1063 (2018)
Chromenone-derived natural products include chromones (flavone, isoflavone) and coumarins. Chromenone compounds not only exhibit impressive biological activities, but also are an important resource of experimentally used fluorophores, such as, 7-amin
Externí odkaz:
https://doaj.org/article/9bf9472371284979bac2f35cb1d40c3d
Publikováno v:
Molecules, Vol 23, Iss 3, p 524 (2018)
Decaprenylphosphoryl-β-d-ribose oxidase (DprE1) is the flavoprotein subunit of decaprenylphosphoryl-d-ribose epimerase involved in cell wall synthesis in Mycobacterium tuberculosis and catalyzes the conversion of decaprenylphosphoryl ribose to decap
Externí odkaz:
https://doaj.org/article/8f7e4329423a4367acc52e6f80838231
A Mild Aqueous Sonogashira Reaction as a Fluorescent Labeling Strategy for 5-Bromide-2′-Deoxyuridine
Publikováno v:
Molecules, Vol 23, Iss 1, p 154 (2018)
C5-modified uridines are a valuable class of nucleoside analogues, both as potent chemotherapy agents and through their use as the conjunction site in DNA labeling strategies. As an important C5-modified uridine, BrdU has been used in cell proliferat
Externí odkaz:
https://doaj.org/article/ba281c50e0d443408bf86c0ab85b96da
Autor:
Yumei Zhou, Huaqing Cui, Xiaoming Yu, Tao Peng, Gang Wang, Xiaoxue Wen, Yunbo Sun, Shuchen Liu, Shouguo Zhang, Liming Hu, Lin Wang
Publikováno v:
Molecules, Vol 22, Iss 8, p 1348 (2017)
A series of benzofuran derivatives were designed and synthesized, and their inhibitory activites were measured against the SIRT1–3. The enzymatic assay showed that all the compounds showed certain anti-SIRT2 activity and selective over SIRT1 and SI
Externí odkaz:
https://doaj.org/article/d1b4be05482741da8ddc79a579503c5b
Autor:
Krishnamurthy, Hari Krishnan, Pereira, Michelle, Rajavelu, Imbaasree, Jayaraman, Vasanth, Krishna, Karthik, Tianhao Wang, Kang Bei, Rajasekaran, John J., Shinya Kato, Huaqing Cui
Publikováno v:
Frontiers in Chemistry; 2024, p01-27, 27p
Publikováno v:
Medicinal Chemistry Research
Herein we report our investigation concerning the development of Human neutrophil elastase (hNE) inhibitors for the treatment of Acute Respiratory Distress Syndrome (ARDS). Various benzenesulfonic acid derived compounds were synthesized and evaluated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93688d4234a0bc7845214a032bc2d7ff
http://europepmc.org/articles/PMC7801566
http://europepmc.org/articles/PMC7801566
Publikováno v:
Journal of Medicinal Chemistry. 64:1001-1017
Herein, we report our work exploring the essential requirements for fluorophore selection during the development of various fluorescence applications. We assembled a library of chromone-derived fluorophores with diverse structure-fluorescence propert
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::387a43a27c51a6f0865fc58fa50910fc
https://doi.org/10.1021/acs.jmedchem.0c01508
https://doi.org/10.1021/acs.jmedchem.0c01508