Zobrazeno 1 - 10
of 283
pro vyhledávání: '"Huanxing Su"'
Publikováno v:
Translational Neurodegeneration, Vol 13, Iss 1, Pp 1-19 (2024)
Abstract Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by progressive loss of motor neurons, resulting in global health burden and limited post-diagnosis life expectancy. Although primarily sporadic, familial
Externí odkaz:
https://doaj.org/article/cc72ef5b16f14117875ab7f4c7c43515
Autor:
Ming‐Yue Wu, Yun‐Jun Ge, Er‐Jin Wang, Qi‐Wen Liao, Zheng‐Yu Ren, Yang Yu, Guoyuan Zhu, Chun‐Ping Liu, Meng‐Ni Zhang, Huanxing Su, Han‐Ming Shen, Ye Chen, Lei Wang, Yi‐Tao Wang, Min Li, Zhaoxiang Bian, Jin Chai, Richard D Ye, Jia‐Hong Lu
Publikováno v:
EMBO Molecular Medicine, Vol 15, Iss 12, Pp n/a-n/a (2023)
Abstract Efficient clearance of dying cells (efferocytosis) is an evolutionarily conserved process for tissue homeostasis. Genetic enhancement of efferocytosis exhibits therapeutic potential for inflammation resolution and tissue repair. However, pha
Externí odkaz:
https://doaj.org/article/2a73d763915d475b830783a8ca0d9a89
Autor:
Cheong-Meng Chong, Yuan Tan, Jiaqi Tong, Minjing Ke, Ke Zhang, Lingli Yan, Xiaotong Cen, Jia-Hong Lu, Guobing Chen, Huanxing Su, Dajiang Qin
Publikováno v:
Cell & Bioscience, Vol 12, Iss 1, Pp 1-15 (2022)
Abstract Background The mammalian target of rapamycin (mTOR) plays a critical role in controlling cellular homeostasis, and its dysregulation has been implicated in Alzheimer’s disease (AD). Presenilin-1 (PS1) mutations account for the most common
Externí odkaz:
https://doaj.org/article/755c73d220034150b8ead9b0e7fa98f7
Autor:
Ke Zhang, Miaodan Huang, Ang Li, Jing Wen, Lingli Yan, Yunhao Li, Liman Guo, Kumaran Satyanarayanan Senthil, Yangyang Zhou, Guobing Chen, Yong Liu, Xiaofei Zhang, Xiaoli Yao, Dajiang Qin, Huanxing Su
Publikováno v:
Cell Reports, Vol 42, Iss 1, Pp 111986- (2023)
Summary: Membraneless condensates, such as stress granules (SGs) and processing bodies (P-bodies), have attracted wide attention due to their unique feature of rapid response to stress without first requiring nuclear feedback. In this study, we ident
Externí odkaz:
https://doaj.org/article/c79dbece46364d8da5c29adff26dcd35
Autor:
Changcheng Lu, Shuhui Qu, Zhangfeng Zhong, Hua Luo, Si San Lei, Hai-Jing Zhong, Huanxing Su, Yitao Wang, Cheong-Meng Chong
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Parkinson’s disease (PD) is an age-related chronic neurodegenerative disease caused by the death and degeneration of dopaminergic neurons in the substantia nigra of the midbrain. The decrease of the neurotransmitter dopamine in the patient’s brai
Externí odkaz:
https://doaj.org/article/3a2d21ae9c794d6ba3de119e21b0ac9d
Autor:
Youna Xie, Lingli Yan, Haitao Zeng, Weineng Chen, Jia-Hong Lu, Jian-Bo Wan, Huanxing Su, Xiaoli Yao
Publikováno v:
Chinese Medicine, Vol 15, Iss 1, Pp 1-11 (2020)
Abstract Background Alzheimer’s disease (AD) is ranked as the most prevalent neurodegenerative disease. However, the exact molecular mechanisms underlying pathophysiological alterations in AD remain unclear, especially at the prodromal stage. The d
Externí odkaz:
https://doaj.org/article/235df669f29a47a6893362e1c6fff49c
Autor:
Zhihua Peng, Hong Zhan, Yijia Shao, Yan Xiong, Lijin Zeng, Cong Zhang, Zhihao Liu, Zhenhua Huang, Huanxing Su, Zhen Yang
Publikováno v:
Chinese Medicine, Vol 15, Iss 1, Pp 1-12 (2020)
Abstract Background Atherosclerosis, the underlying cause of the majority of cardiovascular diseases, is a lipid-driven, inflammatory disease of the large arteries. Atherosclerotic cardiovascular disease (ASCVD) threatens human lives due to high morb
Externí odkaz:
https://doaj.org/article/d358bee6b79346a2b81745a62d1b9ba5
Autor:
Congling Qiu, Chanchan Xiao, Zhigang Wang, Guodong Zhu, Lipeng Mao, Xiongfei Chen, Lijuan Gao, Jieping Deng, Jun Su, Huanxing Su, Evandro Fei Fang, Zhang-Jin Zhang, Jikai Zhang, Caojun Xie, Jun Yuan, Oscar Junhong Luo, Li`an Huang, Pengcheng Wang, Guobing Chen
Publikováno v:
Frontiers in Immunology, Vol 12 (2022)
We identified SARS-CoV-2 specific antigen epitopes by HLA-A2 binding affinity analysis and characterized their ability to activate T cells. As the pandemic continues, variations in SARS-CoV-2 virus strains have been found in many countries. In this s
Externí odkaz:
https://doaj.org/article/ea5a4dcfda90462788d704486092646e
Publikováno v:
Journal of Functional Foods, Vol 81, Iss , Pp 104463- (2021)
Alzheimer’s disease (AD) is acccounting for over 50% of all cases of dementia worldwide. Currently there are no effective treatments available for AD. Plant-based medications and dietary interventions have attracted increasing research interest as
Externí odkaz:
https://doaj.org/article/59bc19260b8447b0a91b72ef6d0c5141
Publikováno v:
Chinese Medicine, Vol 14, Iss 1, Pp 1-10 (2019)
Abstract Alzheimer’s disease (AD) is a common human neurodegenerative disease, which is characterized by the progressive loss of memory and the cognitive impairment. Since the etiology of AD is still unknown, it is extremely difficult to develop th
Externí odkaz:
https://doaj.org/article/bf19ef55ec004f00835c9f63596d5b15