Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Huanshen Gao"'
Publikováno v:
Frontiers in Genetics, Vol 15 (2024)
Studies have indicated that the preservation of joint health and the facilitation of damage recovery are predominantly contingent upon the joint’s microenvironment, including cell-cell interactions, the extracellular matrix’s composition, and the
Externí odkaz:
https://doaj.org/article/d38213f16ca14ad9b62505b0ffa73e15
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 14 (2024)
Osteoporosis, arthritis, and fractures are examples of orthopedic illnesses that not only significantly impair patients’ quality of life but also complicate and raise the expense of therapy. It has been discovered in recent years that the pathophys
Externí odkaz:
https://doaj.org/article/625ff717d0204f61ada7133dacd01e89
Publikováno v:
BMC Musculoskeletal Disorders, Vol 23, Iss 1, Pp 1-8 (2022)
Abstract Objective To evaluate the impact of body mass index (BMI) on the mid-term clinical outcomes and survival in patients receiving a mobile-bearing unicompartmental knee arthroplasty (UKA). Methods We retrospectively collected data from 355 pati
Externí odkaz:
https://doaj.org/article/95fec0e18d044ca09165f461a9878e21
Autor:
Yi Sun, Ping Leng, Pengcheng Guo, Huanshen Gao, Yikai Liu, Chenkai Li, Zhenghui Li, Haining Zhang
Publikováno v:
Molecular Medicine, Vol 27, Iss 1, Pp 1-19 (2021)
Abstract Background Apoptosis of chondrocyte is involved in osteoarthritis (OA) pathogenesis, and mechanical stress plays a key role in this process by activation of Piezo1. However, the negative regulation of signal conduction mediated by mechanical
Externí odkaz:
https://doaj.org/article/3f9102b6d3374e5ba5b1584dda1506b0
Autor:
Haining Zhang, Chenkai Li, Huanshen Gao, Zhenghui Li, Yi Sun, Ping Leng, Pengcheng Guo, Yikai Liu
Publikováno v:
Molecular Medicine, Vol 27, Iss 1, Pp 1-19 (2021)
Molecular Medicine
Molecular Medicine
Background Apoptosis of chondrocyte is involved in osteoarthritis (OA) pathogenesis, and mechanical stress plays a key role in this process by activation of Piezo1. However, the negative regulation of signal conduction mediated by mechanical stress i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b96ba431cf89e99626498b00866de247
https://doi.org/10.1186/s10020-021-00360-w
https://doi.org/10.1186/s10020-021-00360-w
Publikováno v:
BioMed Research International, Vol 2020 (2020)
BioMed Research International
BioMed Research International
Objective. To investigate the effect of small interfering RNA targeting mechanosensitive ion channel protein Piezo1 (Piezo1-siRNA) on abnormal chondrocyte proliferation exposed to mechanical stretch. Methods. Construct and screen effective Piezo1-siR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::158bbe8445a023ac63957f235a0017bd
https://doaj.org/article/97c8b0be7b9247cfac6c639a056b1966
https://doaj.org/article/97c8b0be7b9247cfac6c639a056b1966
Autor:
Haining Zhang, Mengxiong Song, Dawei Li, Pengcheng Guo, Xipeng Xu, Huanshen Gao, Yi Sun, Chenkai Li, Ping Leng, Zhenghui Li
Publikováno v:
International Immunopharmacology. 85:106681
Studying and understanding the mechanism of inflammation in nucleus pulposus is the key to understand and prevent intervertebral disc degeneration. We propose a model of mechanical sensitive ion channel Piezo1 mediated inflammation of nucleus pulposu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::266ea27f64ea401f7dc7220f53efb45d
https://doi.org/10.1016/j.intimp.2020.106681
https://doi.org/10.1016/j.intimp.2020.106681