Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Huansha, Yu"'
Autor:
Meng Yang, Huansha Yu, Hongxiang Feng, Jianghui Duan, Kaige Wang, Bing Tong, Yunzhi Zhang, Wei Li, Ye Wang, Chaoyang Liang, Hongliang Sun, Dingrong Zhong, Bei Wang, Huang Chen, Chengxiang Gong, Qiye He, Zhixi Su, Rui Liu, Peng Zhang
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-14 (2024)
Abstract Background Accurate differentiation between malignant and benign pulmonary nodules, especially those measuring 5–10 mm in diameter, continues to pose a significant diagnostic challenge. This study introduces a novel, precise approach by in
Externí odkaz:
https://doaj.org/article/3bda76672a5d4890b7e287c546eaa4cd
Autor:
Ziyun Shen, Zhihua Huang, Tieyuan Zhu, Jing Zhang, Meixin Teng, Yang Qing, Shiqi Hu, Yang Li, Yanzheng Xiong, Jie Shen, Yiwen Huang, Lele Zhang, Huansha Yu, Jian Chen, Dongchun Ma, Qing Geng, Yan Luo, Gening Jiang, Peng Zhang
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-11 (2024)
Abstract Background With the ongoing prevalence of the emerging variant and global vaccination efforts, the optimal surgical timing for patients with resectable lung cancer in the Omicron-dominant period requires further investigation. Methods This p
Externí odkaz:
https://doaj.org/article/9db840927d834a538b6938152acc1c9d
Autor:
Haoran Xia, Han Zhang, Zheng Ruan, Huibiao Zhang, Liangdong Sun, Hezhong Chen, Yongxin Zhou, Lele Zhang, Dongliang Bian, Xinsheng Zhu, Jing Zhang, Fenghuan Sun, Huansha Yu, Nan Song, Xiaogang Liu, Yuming Zhu, Haiping Zhang, Wenxin He, Jian Chen, Jie Yang, Guohan Chen, Shiliang Xie, Dongfang Tang, Xiaomiao Zhang, Liang Duan, Deping Zhao, Qinchuan Li, Peng Zhang, Gening Jiang
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 9, Iss 1, Pp 1-9 (2024)
Abstract This multicentre, two-arm, phase 2 study aimed to explore the efficacy and safety of neoadjuvant camrelizumab plus chemotherapy or apatinib in patients with initially unresectable stage II–III non-small-cell lung cancer (NSCLC). Eligible p
Externí odkaz:
https://doaj.org/article/c70fe9157fa3420aa6d3b013a78d0ba0
Autor:
Dongliang Bian, Liangdong Sun, Junjie Hu, Liang Duan, Haoran Xia, Xinsheng Zhu, Fenghuan Sun, Lele Zhang, Huansha Yu, Yicheng Xiong, Zhida Huang, Deping Zhao, Nan Song, Jie Yang, Xiao Bao, Wei Wu, Jie Huang, Wenxin He, Yuming Zhu, Gening Jiang, Peng Zhang
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Afatinib, an irreversible ErbB-family blocker, could improve the survival of advanced epidermal growth factor receptor (EGFR)-mutant non-small cell lung cancer patients (NSCLCm+). This phase II trial (NCT04201756) aimed to assess the feasibi
Externí odkaz:
https://doaj.org/article/66ace9c1807645d998c254ed49e8d3df
Autor:
Junjie Hu, Lele Zhang, Haoran Xia, Yilv Yan, Xinsheng Zhu, Fenghuan Sun, Liangdong Sun, Shuangyi Li, Dianke Li, Jin Wang, Ya Han, Jing Zhang, Dongliang Bian, Huansha Yu, Yan Chen, Pengyu Fan, Qiang Ma, Gening Jiang, Chenfei Wang, Peng Zhang
Publikováno v:
Genome Medicine, Vol 15, Iss 1, Pp 1-25 (2023)
Abstract Background Immunotherapy has revolutionized cancer treatment, but most patients are refractory to immunotherapy or acquire resistance, with the underlying mechanisms remaining to be explored. Methods We characterized the transcriptomes of ~9
Externí odkaz:
https://doaj.org/article/0a72fd6a99f54adfb378bdad5583c382
Autor:
Xinsheng Zhu, Liangdong Sun, Nan Song, Wenxin He, Boxiong Xie, Junjie Hu, Jing Zhang, Jie Yang, Jie Dai, Dongliang Bian, Haoran Xia, Fenghuan Sun, Anwen Xiong, Jie Luo, Lele Zhang, Huansha Yu, Ming Liu, Hongcheng Liu, Haifeng Wang, Haiping Zhang, Chang Chen, Chunyan Wu, Liang Duan, Yuming Zhu, Peng Zhang, Gening Jiang
Publikováno v:
BMC Medicine, Vol 20, Iss 1, Pp 1-15 (2022)
Abstract Background This trial aimed to analyse the safety, effectiveness and transcriptomic characteristics of neoadjuvant toripalimab plus chemotherapy in II–III non-small-cell lung cancer (NSCLC). Methods Patient eligibility mainly involved trea
Externí odkaz:
https://doaj.org/article/be4ff59fe79c46a68cf6410a5d5244c2
Autor:
Dianke Li, Huansha Yu, Junjie Hu, Shaoling Li, Yilv Yan, Shuangyi Li, Liangdong Sun, Gening Jiang, Likun Hou, Lele Zhang, Peng Zhang
Publikováno v:
Journal of Translational Medicine, Vol 20, Iss 1, Pp 1-21 (2022)
Abstract Background The diversity of histologic composition reflects the inter- and intra-tumor heterogeneity of lung adenocarcinomas (LUADs) macroscopically. Insights into the oncological characteristics and tumor microenvironment (TME) of different
Externí odkaz:
https://doaj.org/article/a0a51cdb093447b380946de27b58993d
Autor:
Yicheng Xiong, Dongliang Bian, Zhida Huang, Huansha Yu, Jie Huang, Peng Zhang, Wenxin He, Hongcheng Liu
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
BackgroundEpidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) could provide survival benefits for locally advanced EGFR-mutant (EGFRm) non-small cell lung cancer (NSCLC). However, the role of radical surgery for EGFR-TKI treated s
Externí odkaz:
https://doaj.org/article/0e1b75c723194e4d9d0b52702f0c7517
Autor:
Jing Zhang, Haiping Zhang, Lele Zhang, Dianke Li, Mengfan Qi, Liping Zhang, Huansha Yu, Di Wang, Gening Jiang, Xujun Wang, Xianmin Zhu, Peng Zhang
Publikováno v:
Advanced Genetics, Vol 3, Iss 2, Pp n/a-n/a (2022)
Abstract Small cell lung cancer (SCLC) is a deadly neuroendocrine malignancy with high metastasis. However, the heterogeneity of metastatic SCLC at the single‐cell level remains elusive. The single‐cell transcriptome of a total of 24 081 cells in
Externí odkaz:
https://doaj.org/article/018ba83f36e0482b9a1b7a13f28c3a14
Autor:
Jin Wang, Dongbo Jiang, Xiaoqi Zheng, Wang Li, Tian Zhao, Di Wang, Huansha Yu, Dongqing Sun, Ziyi Li, Jian Zhang, Zhe Zhang, Likun Hou, Gening Jiang, Ke Fei, Fan Zhang, Kun Yang, Peng Zhang
Publikováno v:
iScience, Vol 25, Iss 3, Pp 103883- (2022)
Summary: Knowledge of the tumor microenvironment (TME) in patients with early lung cancer, especially in comparison with the matched adjacent tissues, remains lacking. To characterize TME of early-stage lung adenocarcinoma, we performed RNA-seq profi
Externí odkaz:
https://doaj.org/article/7bf25d1617f44c09b04129b6cff2c5a9