Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Huanpeng, Chen"'
Autor:
Bolan Yu, Huanpeng Chen, Yuying Yang, Yuqing Deng, Fengjiao Wei, Qingyu Zhao, Yongqi Liu, Zhonghua Liu, Zhaofeng Huang
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 2 (2022)
Background Chimeric antigen receptor (CAR) T cell therapy has been successfully applied in treating lymphoma malignancies, but not in solid tumors. CD47 is highly expressed on tumor cells and its overexpression is believed to inhibit phagocytosis by
Externí odkaz:
https://doaj.org/article/1a2dd5019fbf4046aa05cb2f2ac6505c
Autor:
Xiaoqing Zhou, Huanpeng Chen, Fengjiao Wei, Qingyu Zhao, Qiao Su, Jinhao Liang, Meng Yin, Xuyan Tian, Zhonghua Liu, Bolan Yu, Chuan Bai, Xixin He, Zhaofeng Huang
Publikováno v:
Journal of Immunology Research, Vol 2019 (2019)
Th17 activity has been implicated in systemic lupus erythematosus (SLE), which is a systemic autoimmune disease with a typical clinical manifestation of lupus nephritis (LN). Retinoic acid receptor-related orphan receptor gamma t (RORγt) has been sh
Externí odkaz:
https://doaj.org/article/5878996624304d96b30f580a20966614
Autor:
Jiayi, Zhou, Huanpeng, Chen, Xiuting, Xu, Yunyun, Liu, Shengzhu, Chen, Si, Yang, Fang, He, Bolan, Yu
Publikováno v:
Placenta. 119:8-16
Placenta accreta spectrum (PAS) disorder is one of the major complications resulting in maternal death and serious adverse pregnancy outcomes. Uterine damage - principally that associated with cesarean section - is the leading risk factor for the dev
Autor:
Chuan Bai, Xuyan Tian, Huanpeng Chen, Fengjiao Wei, Zhonghua Liu, Xiaoqing Zhou, Bolan Yu, Zhaofeng Huang, Xixin He
Publikováno v:
Immunologic Research. 69:378-390
Retinoic‑acid‑receptor‑related orphan nuclear hormone receptor gamma t (RORγt), a critical transcriptional factor of Th17 cells, is a potential therapeutic target for Th17-mediated autoimmune diseases. In addition, RORγt is essential for thym
Autor:
Xiaoxie Xu, Jun Huang, Mei Zhao, Huanpeng Chen, Jinhua Mo, Xiaoqing Zhou, Qiao Su, Bolan Yu, Zhaofeng Huang
Publikováno v:
Journal of Immunology Research, Vol 2017 (2017)
Autoimmune lymphoproliferative syndrome (ALPS) is an incurable disease mainly caused by the defect of Fas-mediated apoptosis and characterized by nonmalignant autoimmune lymphoproliferation. Stabilized β-catenin could not only potentiate Fas-mediate
Externí odkaz:
https://doaj.org/article/57529715faf54a6394fa181d8c54d1c9
Autor:
Yu Lei, Boyang Zhang, Longxiang Sheng, Xuyan Tian, Chuan Bai, Xiaoting Xu, Xixin He, Huanpeng Chen, Yuying Yang, Fengjiao Wei, Li Yongchao, Zhaofeng Huang, Lipeng Tang, Bolan Yu, Zhonghua Liu, Xiaoqing Zhou
Publikováno v:
Molecular Immunology. 132:30-40
Psoriasis is a refractory inflammatory skin disease affecting 2 %-3 % of the world population, characterized by the infiltration and hyper-proliferation of inflammatory cells and aberrant differentiation of keratinocytes. Targeting the IL-23/ Th17 ax
Autor:
Huanpeng Chen, Yuying Yang, Yuqing Deng, Fengjiao Wei, Qingyu Zhao, Yongqi Liu, Zhonghua Liu, Bolan Yu, Zhaofeng Huang
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 2 (2022)
BackgroundChimeric antigen receptor (CAR) T cell therapy has been successfully applied in treating lymphoma malignancies, but not in solid tumors. CD47 is highly expressed on tumor cells and its overexpression is believed to inhibit phagocytosis by m
Publikováno v:
SSRN Electronic Journal.
Publikováno v:
Cancer immunology, immunotherapy : CII. 70(7)
Chimeric antigen receptor (CAR) T cell therapy, a type of adoptive cell therapy, has been successfully used when treating lymphoma malignancies, but not nearly as successful in treating solid tumors. Trophoblast cell surface antigen 2 (Trop2) is expr
Publikováno v:
Bioorganic chemistry. 90
Retinoid-related orphan receptor gamma-t (RORγt) belongs to the nuclear receptor superfamily that takes vital roles in the development and maturation of T-helper 17 cell (Th17) and lymph-node genesis. Because Th17 cells have been proved to be major