Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Huanling Cao"'
Autor:
Xueying Zhang, Lili Pian, Beifen Shen, Guihua Qiu, Huanling Cao, Yaolin Zhang, Jing-Ru Huang, Xuetao Cao, Jie Dong, Xin Li, Jian Liu, Zhe Xu, Yawei Zhao, Huang Xiaofeng, Lu Guo, Jiyan Zhang, Xiaomin Ying, Weiping J Zhang, Hong-Xia Wang
Publikováno v:
Proc Natl Acad Sci U S A
Neddylation is a ubiquitination-like pathway that controls cell survival and proliferation by covalently conjugating NEDD8 to lysines in specific substrate proteins. However, the physiological role of neddylation in mammalian metabolism remains elusi
Autor:
SILEI ZHOU1,2, HUANLING CAO1,2, YAWEI ZHAO1,2, XINYING LI1, JIYAN ZHANG1, CHUNMEI HOU1, YUANFANG MA2 mayf@henu.edu.cn, QINGYANG WANG1 tansun0532@163.com
Publikováno v:
Oncology Letters. Dec2016, Vol. 12 Issue 6, p5303-5308. 6p.
Autor:
Beifen Shen, Kun Han, Junxia Cao, Huanling Cao, Guihua Qiu, Xin Li, Jiyan Zhang, Jing Wang, Qingyang Wang
Publikováno v:
Oncotarget
The first-in-class compound MLN4924 is a small molecule inhibitor that selectively inactivates NEDD8-activating enzyme (NAE). The anticancer effects of MLN4924 have been attributed to impaired neddylation of Cullin proteins. Here, we show that treatm
Autor:
Xin Li, Jing Wang, Yujun Pei, Lu Guo, Huanling Cao, Beifen Shen, Qingyang Wang, Jing Xie, Jiyan Zhang, Guihua Qiu, Huifang Wu, Hu Chen, Jian Liu, Lei Hua, Kun Han, Suoqin Tang, Zhaofei Jing, Jiayang Jin, Jun Zhang
Publikováno v:
Leukemialymphoma. 59(5)
All-trans retinoic acid (ATRA) has demonstrated notable success in the treatment of acute promyelocytic leukemia (APL) by inducing granulocytic differentiation. The underlying mechanisms of ATRA therapeutic effects have not been entirely clarified. H