Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Huankai Yao"'
Publikováno v:
Journal of Functional Foods, Vol 110, Iss , Pp 105842- (2023)
Diabetic nephropathy (DN) is one of the severe microvascular complications of diabetes mellitus and it was proved activation of nuclear factor erythroid 2-related factor 2 (Nrf2) could attenuate DN. To find Nrf2 activators, we explored tiliroside ide
Externí odkaz:
https://doaj.org/article/c3640889f74f495e8a130ad8f7cefad5
Publikováno v:
Redox Report, Vol 27, Iss 1, Pp 230-238 (2022)
Objectives Diabetic nephropathy (DN) is one of the most common microvascular complications of diabetes mellitus. Oxidative stress resulting from high glucose promotes accumulation of ECM and development of DN. Activation of Nrf2 could attenuate oxida
Externí odkaz:
https://doaj.org/article/30969d67e0584b93822b67fcb3f2b664
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 37, Iss 1, Pp 178-188 (2022)
Diabetic nephropathy (DN) is one of the severe microvascular complications of diabetes mellitus. Oxidative stress resulting from aberrant metabolism of glucose mediates renal inflammation and fibrosis in the progression of DN. Nuclear factor erythroi
Externí odkaz:
https://doaj.org/article/917569a986b448abbd033fc8100ba29f
Publikováno v:
Frontiers in Chemistry, Vol 10 (2022)
Reprogramming cancer metabolism has become the hallmark of cancer progression. As the key enzyme catalyzing the conversion of pyruvate to lactate in aerobic glycolysis of cancer cells, human lactate dehydrogenase (LDH) has been a promising target in
Externí odkaz:
https://doaj.org/article/10f3687f26ce484c9d717d765e2385c7
Publikováno v:
PLoS ONE, Vol 15, Iss 11, p e0243066 (2020)
Candidiasis causes high morbidity and mortality among immunocompromised patients. Antifungal drug resistance and cytotoxicity highlight the need of effective antifungal therapeutics. In this study, we found that kalopanaxsaponin A (KPA), a triterpeno
Externí odkaz:
https://doaj.org/article/0fa78075746a4cfe8850b0bef083d84c
Autor:
Ying Li, Mingzhu Shan, Mingju Yan, Huankai Yao, Yuechen Wang, Bing Gu, Zuobin Zhu, Hongchun Li
Publikováno v:
Frontiers in Microbiology, Vol 10 (2019)
BackgroundThe pathogenicity of Candida albicans is attributed to various virulence factors including adhesion to the surface of epithelial cells or mucosa, germ tube formation, hyphal morphogenesis, development of drug resistant biofilms, and so on.
Externí odkaz:
https://doaj.org/article/eb3aa26aed7d462da9caa63763707ff4
Publikováno v:
Redox report : communications in free radical research. 27(1)
Diabetic nephropathy (DN) is one of the most common microvascular complications of diabetes mellitus. Oxidative stress resulting from high glucose promotes accumulation of ECM and development of DN. Activation of Nrf2 could attenuate oxidative stress
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e19e6c1ba2881e16d4c6fc47d040fee9
https://pubmed.ncbi.nlm.nih.gov/36259553
https://pubmed.ncbi.nlm.nih.gov/36259553
Publikováno v:
Journal of Natural Medicines. 75:1021-1029
Diabetic nephropathy (DN) is one of the most common microvascular complications of diabetes mellitus and becomes the financial burden and health problem. Pathogenesis of DN has revealed that high glucose has resulted in the oxidative stress and accum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb05cc156742f3b56bb6a8f37bb00f93
https://doi.org/10.1007/s11418-021-01534-w
https://doi.org/10.1007/s11418-021-01534-w
Publikováno v:
Journal of Natural Medicines. 75:178-185
Triple negative breast cancer (TNBC) is the most severe type of breast cancer due to the lack of specific targets and rapid metastasis, which result in the poor prognosis. Recently, phosphatidylinositol 3-kinase (PI3K)/Akt pathway has emerged as a po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::459f2b0af919697cd2df4078f143d022
https://doi.org/10.1007/s11418-020-01447-0
https://doi.org/10.1007/s11418-020-01447-0
Publikováno v:
Medicinal Chemistry Research. 29:103-112
Cerebral ischemic stroke is a severe cause of disability and death among people worldwide. The occlusion of cerebral blood flow has resulted in the infarction due to the oxygen and glucose deprivation. Though timely reperfusion can reduce the infarct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a6b6ed7df06a3f688e58c899c11a1b05
https://doi.org/10.1007/s00044-019-02464-9
https://doi.org/10.1007/s00044-019-02464-9