Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Huangyao Chen"'
Autor:
Shuangshuang Mu, Huangyao Chen, Qianru Li, Shixue Gou, Xiaoyi Liu, Junwei Wang, Wei Zheng, Menglong Chen, Qin Jin, Liangxue Lai, Kepin Wang, Hui Shi
Publikováno v:
Genome Biology, Vol 25, Iss 1, Pp 1-19 (2024)
Abstract Background Prime editing enables precise base substitutions, insertions, and deletions at targeted sites without the involvement of double-strand DNA breaks or exogenous donor DNA templates. However, the large size of prime editors (PEs) ham
Externí odkaz:
https://doaj.org/article/5d0ea2f60dda49b2aa237e960f70f26e
Autor:
Ting Lan, Huangyao Chen, Chengcheng Tang, Yuhui Wei, Yang Liu, Jizeng Zhou, Zhenpeng Zhuang, Quanjun Zhang, Min Chen, Xiaoqing Zhou, Yue Chi, Jinling Wang, Yu He, Liangxue Lai, Qingjian Zou
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 33, Iss , Pp 890-897 (2023)
Prime editor (PE) is a versatile genome editing tool that does not need extra DNA donors or inducing double-strand breaks. However, in vivo implementation of PE remains a challenge because of its oversized composition. In this study, we screened out
Externí odkaz:
https://doaj.org/article/8627ee1167194107a2672a4ab7f37199
Autor:
Yang Liu, Yang Yang, Yangyang Suo, Chuan Li, Min Chen, Shuwen Zheng, Hao Li, Chengcheng Tang, Nana Fan, Ting Lan, Jizeng Zhou, Yingying Li, Jiaowei Wang, Huangyao Chen, Qingjian Zou, Liangxue Lai
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 24, Iss , Pp 332-341 (2022)
Pluripotent stem cells (PSCs) are promising in regenerative medicine. A major challenge of PSC therapy is the risk of teratoma formation because of the contamination of undifferentiated stem cells. Constitutive promoters or endogenous SOX2 promoters
Externí odkaz:
https://doaj.org/article/816ae9b9e7cd405baf12a610222efcf9
Autor:
Ting Lan, Yuling Zheng, Yangyang Suo, Yuhui Wei, Hui Shi, Quanmei Yan, Zhenpeng Zhuang, Huangyao Chen, Quanjun Zhang, Nana Fan, Yu Zhao, Zhen Ouyang, Chengdan Lai, Zhaoming Liu, Jizeng Zhou, Chengcheng Tang, Nam-Hyung Kim, Qingjian Zou, Xiaomin Wang
Publikováno v:
Journal of Genetics and Genomics. 50:212-215
Autor:
Yingying Li, Hai Wang, Huangyao Chen, Yuan Liao, Shixue Gou, Quanmei Yan, Zhenpeng Zhuang, Hao Li, Jiaowei Wang, Yangyang Suo, Ting Lan, Yang Liu, Yu Zhao, Qingjian Zou, Tao Nie, Xiaoyan Hui, Liangxue Lai, Donghai Wu, Nana Fan
Publikováno v:
The FASEB Journal. 36
Autor:
Jun Liu, Yingying Mao, Qingqing Li, Zhenzhen Qiu, Jingjing Li, Xiaoxin Li, Wenhan Liang, Mingyu Xu, Andrew Li, Xiangsheng Cai, Wangsheng Wu, Huangyao Chen, Renhe Yan, Jinlong Li, Weiwang Gu, Hongwei Li
Publikováno v:
Human gene therapy. 33(23-24)
Gene therapy's entrance into clinical settings has made it an ever more attractive field of study for various diseases. However, relatively little progress has been made in targeting kidney diseases due to poor gene delivery efficiency in renal cells
Autor:
Yingying, Li, Hai, Wang, Huangyao, Chen, Yuan, Liao, Shixue, Gou, Quanmei, Yan, Zhenpeng, Zhuang, Hao, Li, Jiaowei, Wang, Yangyang, Suo, Ting, Lan, Yang, Liu, Yu, Zhao, Qingjian, Zou, Tao, Nie, Xiaoyan, Hui, Liangxue, Lai, Donghai, Wu, Nana, Fan
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental BiologyREFERENCES. 36(11)
Obesity is among the strongest risk factors for type 2 diabetes (T2D). The CREBRF missense allele rs373863828 (p. Arg457Gln, p. R457Q) is associated with increased body mass index but reduced risk of T2D in people of Pacific ancestry. To investigate