Zobrazeno 1 - 10
of 81
pro vyhledávání: '"Huangxuan Shen"'
Autor:
Yilin Shi, Huangxuan Shen
Publikováno v:
Frontiers in Genetics, Vol 14 (2023)
Stomach Adenocarcinoma (STAD) is a leading cause of death worldwide. Somatic Copy Number Alterations (SCNAs), which result in Homologous recombination (HR) deficiency in double-strand break repair, are associated with the progression of STAD. However
Externí odkaz:
https://doaj.org/article/a8beed9c58cf4ee09bf0577befddf06a
Publikováno v:
BMC Complementary Medicine and Therapies, Vol 23, Iss 1, Pp 1-12 (2023)
Abstract Background Age-related macular degeneration (AMD) is a leading cause of vision loss in elderly people, and dry AMD is the most common type of AMD. Oxidative stress and alternative complement pathway activation may play essential roles in the
Externí odkaz:
https://doaj.org/article/73fc7ab7b396493fa98fa3bc416127a0
Autor:
Han Tang, Han Du, Xielan Kuang, Hao Huang, Jingshu Zeng, Chongde Long, Binbin Zhu, Licheng Fu, Hua Wang, Qingjiong Zhang, Shuibin Lin, Jianhua Yan, Huangxuan Shen
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
Age-related macular degeneration (AMD), which is the leading cause of blindness among the elderly in western societies, is majorly accompanied by retinal pigment epithelium (RPE) degeneration. Because of the irreversible RPE cell loss among oxidative
Externí odkaz:
https://doaj.org/article/81923bbedc9c481b8adcd75d3105c79e
Autor:
Qing Xia, Xiangtian Ling, Zhonghao Wang, Tao Shen, Minghao Chen, Danyi Mao, Xinqi Ma, Jie Ning, Han Zhang, Dongli Chen, Qiong Gu, Huangxuan Shen, Jianhua Yan
Publikováno v:
BMC Ophthalmology, Vol 21, Iss 1, Pp 1-8 (2021)
Abstract Purpose and background Recently, we found that maximal medial rectus recession and lateral rectus resection in patients with complete lateral rectus paralysis resulted in a partial restoration of abduction. In an attempt to understand some o
Externí odkaz:
https://doaj.org/article/6074f463227041a8b9a787bfc54405bc
Publikováno v:
Frontiers in Medicine, Vol 8 (2022)
PurposeTo review the surgical procedures and outcomes of supramaximal horizontal rectus recession–resection surgery for abduction deficiency and esotropia resulting from complete unilateral abducens nerve palsy.MethodsA total of 36 consecutive case
Externí odkaz:
https://doaj.org/article/71e4ebabdc1b4eebb4766f74d93349c1
Autor:
Xin Zhou, Jennifer W Li, Zirong Chen, Wei Ni, Xuehui Li, Rongqiang Yang, Huangxuan Shen, Jian Liu, Francesco J DeMayo, Jianrong Lu, Frederic J Kaye, Lizi Wu
Publikováno v:
eLife, Vol 10 (2021)
Lung cancer with loss-of-function of the LKB1 tumor suppressor is a common aggressive subgroup with no effective therapies. LKB1-deficiency induces constitutive activation of cAMP/CREB-mediated transcription by a family of three CREB-regulated transc
Externí odkaz:
https://doaj.org/article/1b1857557a5e4d92b64355dc39042367
Autor:
Yarong Dai, Maosheng Cheng, Siyan Zhang, Rongsong Ling, Jieqi Wen, Yifan Cheng, Boxuan Huang, Jinrong Li, Caifeng Dai, Shiqing Mao, Shuibin Lin, Huangxuan Shen, Yizhou Jiang
Publikováno v:
Stem Cells International, Vol 2021 (2021)
Limbal stem cells are essential for continuous corneal regeneration and injury repair. METTL3-catalyzed N6-methyladenosine (m6A) mRNA modifications are involved in many biological processes and play a specific role in stem cell regeneration, while th
Externí odkaz:
https://doaj.org/article/67fb4ff9e993473cb06ce8a1f0056837
Autor:
Weiwei Liu, Guorong Jin, Chongde Long, Xin Zhou, Yan Tang, Shan Huang, Xielan Kuang, Lizi Wu, Qingjiong Zhang, Huangxuan Shen
Publikováno v:
The Scientific World Journal, Vol 2013 (2013)
The Notch signaling is an evolutionarily conserved cell-cell communication pathway that plays critical roles in the proliferation, survival, apoptosis, and fate determination of mammalian cells. Retinal pigment epithelial (RPE) cells are responsible
Externí odkaz:
https://doaj.org/article/e709d8f515bf492f8ee7c73e87ef0762
Autor:
Jiamin Ouyang, Wenmin Sun, Huangxuan Shen, Xing Liu, Yingchen Wu, Hongmei Jiang, Xueqing Li, Yingwei Wang, Yi Jiang, Shiqiang Li, Xueshan Xiao, J. Fielding Hejtmancik, Zhiqun Tan, Qingjiong Zhang
Publikováno v:
Human Genetics. 142:103-123
Mutations in myelin regulatory factor (MYRF), a gene mapped to 11q12-q13.3, are responsible for autosomal dominant high hyperopia and seem to be associated with angle closure glaucoma, which is one of the leading causes of irreversible blindness worl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d5aaa891f903c80751fc23734fb40c7
https://doi.org/10.1007/s00439-022-02487-0
https://doi.org/10.1007/s00439-022-02487-0
Autor:
Yubo Tang, Qingde Wa, Longyun Peng, Yifan Zheng, Jie Chen, Xiao Chen, Xuenong Zou, Huangxuan Shen, Shuai Huang
Publikováno v:
Oxidative Medicine and Cellular Longevity. 2022:1-22
Mounting evidence demonstrates uncontrolled endoplasmic reticulum (ER) stress responses can activate the inflammasome, which generally results in endothelial dysfunction, a major pathogenetic factor of chronic inflammatory diseases such as atheroscle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::107c0a5f99dae0ea1ae93073fec8f9f1
https://doi.org/10.1155/2022/8332825
https://doi.org/10.1155/2022/8332825