Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Huangliang Zheng"'
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Respiratory Staphylococcus aureus infection represents a common complication in lung cancer patients, which is characterized with progressively and recurrently intratumor invasion. Although bacteriophages are widely reported as an effective
Externí odkaz:
https://doaj.org/article/c5fd495ee984430cafdff87798440ea6
Publikováno v:
Pharmaceutics, Vol 14, Iss 6, p 1223 (2022)
The multi-inlet vortex mixer (MIVM) has emerged as a novel bottom-up technology for solid nanoparticle preparation. However, its performance in liposome preparation remains unknown. Here, two key process parameters (aqueous/organic flow rate ratio (F
Externí odkaz:
https://doaj.org/article/b9421ce017bc4d61b590416ee45bb5c4
Autor:
Xiang Luo, Ling Hu, Huangliang Zheng, Mingqi Liu, Xinrong Liu, Cong Li, Qiujun Qiu, Zitong Zhao, Xiaobo Cheng, Chaoyang Lai, Yuqing Su, Yihui Deng, Yanzhi Song
Publikováno v:
Drug Delivery, Vol 25, Iss 1, Pp 1200-1212 (2018)
Poly(sialic acid) (PSA) is a natural hydrophilic biodegradable and non-immunogenic biopolymer, receptors for its monomer are expressed on peripheral blood neutrophils (PBNs), which plays important roles in the progression and invasion of tumors. A po
Externí odkaz:
https://doaj.org/article/3fff596edbd044a2946dac9ea8aaa9b7
Publikováno v:
Pharmaceutical Research.
Bacterial infections in the respiratory tract are considered as one of the major challenges to the public health worldwide. Pulmonary delivery is an attractive approach in the management of bacterial respiratory infections with a few inhaled antibiot
Autor:
Huangliang Zheng, Michael Moehwald, Linc Chen, Shirui Mao, Yuyang Zhang, Xiaoran Li, Chenhong Guo, Moritz Beck-Broichsitter, Jiaqi Li, Ying Sun, Lu Qin, Jian Su
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics. 143:70-79
Controlled drug delivery to the lungs is promising with plentiful advantages over current rapid release products. However, alveolar macrophage clearance has severely hindered the application of inhaled controlled release preparations. The objective o
Autor:
Lan Zhang, Uwe Muenster, Yuyang Zhang, Jiaqi Li, Lu Qin, Linc Chen, Linglong Yang, Huangliang Zheng, Shirui Mao, Linlin Fan, Xiaofei Zhang, En-Yu Xu, Moritz Beck-Broichsitter
Publikováno v:
Acta Biomaterialia. 96:505-516
Large porous particles (LPPs) are well-known vehicles for drug delivery to the lungs. However, it remains uncertain whether or to which extent the in vitro drug release behavior of LPPs can be predictive of their in vivo performance (e.g., systemic e
Autor:
Qiujun Qiu, Yanzhi Song, Ling Hu, Cong Li, Jiaqi Li, Yihui Deng, Xiang Luo, Huangliang Zheng, Mengjing Wang
Publikováno v:
International Journal of Pharmaceutics. 558:187-200
To overstep the dilemma of chemical drug degradation within powerful lysosomes of tumor associated macrophages (TAMs), a sialic acid-polyethylenimine-cholesterol (SA-PEI-CH) modified liposomal doxorubicin (DOX-SPCL) was designed with both TAMs target
Autor:
Yanzhi Song, Cong Li, Yihui Deng, Qiujun Qiu, Jiaqi Li, Xiang Luo, Junqiang Ding, Huangliang Zheng, Ling Hu
Publikováno v:
Cancer Chemotherapy and Pharmacology. 83:361-374
Macrophage-mediated drug delivery system has emerged and gained wide interest as a novel strategy for cancer treatment. Among them, RAW264.7 cell was commonly used as the macrophage model for antitumor drug loading and delivery. However, this cell li
Publikováno v:
Acta biomaterialia. 123
Polyethylene glycol (PEG) modification is one of the promising approaches to overcome both mucus and alveolar macrophage uptake barriers in the deep lung for sustained therapy of pulmonary diseases such as asthma. To investigate the feasibility of us
Autor:
Huangliang Zheng, Yihui Deng, Xinrong Liu, Hongxia Zhang, Ling Hu, Qiujun Qiu, Cong Li, Yanzhi Song, Yi Lu, Xiang Luo, Chaoyang Lai, Min Liu
Publikováno v:
AAPS PharmSciTech. 20(5)
Mannose receptor (CD206) and E-selectin are selectively expressed in M2-like tumor-associated macrophages (M2-TAMs) and activated endothelial cells of vessels surrounding tumor tissues. With the knowledge that D-mannose is the natural ligand of manno