Zobrazeno 1 - 10
of 138
pro vyhledávání: '"Huanghe Yang"'
Autor:
Ke Zoe Shan, Trieu Le, Pengfei Liang, Ping Dong, Lowry, Augustus J., Kremmyda, Polina, Claesson-Welsh, Lena, Huanghe Yang
Publikováno v:
Journal of Cell Science; 7/15/2024, Vol. 137 Issue 14, p1-9, 9p
Autor:
Ping Dong, Bakhurin, Konstantin, Yuhui Li, Mikati, Mohamad A., Jianmin Cui, Grill, Warren M., Yin, Henry H., Huanghe Yang
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America; 7/9/2024, Vol. 121 Issue 28, p1-12, 23p
Autor:
Yang Zhang, Pengfei Liang, Liheng Yang, Ke Zoe Shan, Liping Feng, Yong Chen, Wolfgang Liedtke, Carolyn B Coyne, Huanghe Yang
Publikováno v:
eLife, Vol 11 (2022)
TMEM16F, a Ca2+-activated phospholipid scramblase (CaPLSase), is critical for placental trophoblast syncytialization, HIV infection, and SARS-CoV2-mediated syncytialization, however, how TMEM16F is activated during cell fusion is unclear. Here, using
Externí odkaz:
https://doaj.org/article/188cd88aef404e6bb7b35887032a65f2
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
The transmembrane protein 16 (TMEM16) family consists of Ca2+-activated ion channels and Ca2+-activated phospholipid scramblases (CaPLSases) that passively flip-flop phospholipids between the two leaflets of the membrane bilayer. Owing to their diver
Externí odkaz:
https://doaj.org/article/53cba41171754598a160f74ffca01b60
Publikováno v:
Journal of Cell Science; Mar2024, Vol. 137 Issue 5, p1-9, 9p
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
The calcium-activated chloride channel (CaCC) TMEM16A plays crucial roles in regulating neuronal excitability and muscle contraction. Here authors show that phosphatidylinositol (4,5)-bisphosphate (PIP2) regulates TMEM16A channel activation and desen
Externí odkaz:
https://doaj.org/article/7a7fbea43b5a481ab048b4ad58174d2f
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
TMEM16F is an enigmatic Ca2 + -activated phospholipid scramblase (CaPLSase) that passively transports phospholipids. Here authors identify an inner activation gate and its disruption profoundly alters TMEM16F phospholipid permeation.
Externí odkaz:
https://doaj.org/article/ff04ecc72037485988bec5dbf32407c6
Autor:
Qingyu Zhou, Justin Doherty, Antonina Akk, Luke E. Springer, Ping Fan, Ivan Spasojevic, Ganesh V. Halade, Huanghe Yang, Christine T. N. Pham, Samuel A. Wickline, Hua Pan
Publikováno v:
Nanomaterials, Vol 12, Iss 3, p 336 (2022)
Cancer treatment-induced toxicities may restrict maximal effective dosing for treatment and cancer survivors’ quality of life. It is critical to develop novel strategies that mitigate treatment-induced toxicity without affecting the efficacy of ant
Externí odkaz:
https://doaj.org/article/dcc9257127ab4ef79e27f0f7a34e4b4c
Autor:
Qing Zhang, Charles M. Perou, Huanghe Yang, Yan Peng, Einars Loza, Victor G. Andrianov, Travis S. Ptacek, Jeremy M. Simon, Lianxin Hu, Giada Zurlo, Jin Zhou, Mamoru Takada, Jason W. Locasale, Juan Liu, Laura E. Herring, Cheng Fan, Yang Zhang, Chengheng Liao
Triple-negative breast cancer (TNBC) is an aggressive and highly lethal disease. Because of its heterogeneity and lack of hormone receptors or HER2 expression, targeted therapy is limited. Here, by performing a functional siRNA screening for 2-OG–d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8a61a0fd9b7345fe85ece52174cd560c
https://doi.org/10.1158/2159-8290.c.6547829.v1
https://doi.org/10.1158/2159-8290.c.6547829.v1
Autor:
Qing Zhang, Charles M. Perou, Huanghe Yang, Yan Peng, Einars Loza, Victor G. Andrianov, Travis S. Ptacek, Jeremy M. Simon, Lianxin Hu, Giada Zurlo, Jin Zhou, Mamoru Takada, Jason W. Locasale, Juan Liu, Laura E. Herring, Cheng Fan, Yang Zhang, Chengheng Liao
Table S1. List of 65 2-OG dioxygenases
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ade5c80f5497c480f31fe643d507fd4
https://doi.org/10.1158/2159-8290.22535315.v1
https://doi.org/10.1158/2159-8290.22535315.v1