Zobrazeno 1 - 10
of 174
pro vyhledávání: '"Huang-tian Yang"'
Autor:
Yun Jiang, Ling-Ling Zhang, Fan Zhang, Wei Bi, Peng Zhang, Xiu-Jian Yu, Sen-Le Rao, Shi-Hui Wang, Qiang Li, Chen Ding, Ying Jin, Zhong-Min Liu, Huang-Tian Yang
Publikováno v:
Bioactive Materials, Vol 28, Iss , Pp 206-226 (2023)
Human pluripotent stem cell-derived cardiovascular progenitor cells (hCVPCs) and cardiomyocytes (hCMs) possess therapeutic potential for infarcted hearts; however, their efficacy needs to be enhanced. Here we tested the hypotheses that the combinatio
Externí odkaz:
https://doaj.org/article/75f793f3589d430db82a6e8fd62b11da
Autor:
Xiao‐Ling Luo, Yun Jiang, Qiang Li, Xiu‐Jian Yu, Teng Ma, Hao Cao, Min‐Xia Ke, Peng Zhang, Ji‐Liang Tan, Yan‐Shan Gong, Li Wang, Ling Gao, Huang‐Tian Yang
Publikováno v:
Advanced Science, Vol 10, Iss 27, Pp n/a-n/a (2023)
Abstract Myocardial infarction (MI) causes excessive damage to the myocardium, including the epicardium. However, whether pluripotent stem cell‐derived epicardial cells (EPs) can be a therapeutic approach for infarcted hearts remains unclear. Here,
Externí odkaz:
https://doaj.org/article/e660f9b2dc8b4436a58f931cda88c46b
Autor:
Wei Bi, Jinxi Wang, Yun Jiang, Qiang Li, Shihui Wang, Meilan Liu, Qiao Liu, Fang Li, Christian Paul, Yigang Wang, Huang‐Tian Yang
Publikováno v:
Stem Cells Translational Medicine, Vol 10, Iss 5, Pp 756-772 (2021)
Abstract Acute myocardial infarction (MI) resulting from coronary ischemia is a major cause of disability and death worldwide. Transplantation of human embryonic stem cell (hESC)‐derived cardiovascular progenitor cells (hCVPCs) promotes the healing
Externí odkaz:
https://doaj.org/article/3f4e74cf59b04524a656165bfa0f2e27
Publikováno v:
Stem Cells Translational Medicine, Vol 9, Iss 10, Pp 1121-1128 (2020)
Abstract Heart diseases (HDs) are the leading cause of morbidity and mortality worldwide. Despite remarkable clinical progress made, current therapies cannot restore the lost myocardium, and the correlation of genotype to phenotype of many HDs is poo
Externí odkaz:
https://doaj.org/article/399f16533570466b9a088a0a4c52816c
Publikováno v:
Stem Cell Research & Therapy, Vol 11, Iss 1, Pp 1-16 (2020)
Abstract Background Mesendodermal formation during early gastrulation requires the expression of lineage-specific genes, while the regulatory mechanisms during this process have not yet been fully illustrated. TATA box-binding protein (TBP) and TBP-l
Externí odkaz:
https://doaj.org/article/b5e232323313498b8d6a39776157dde0
Publikováno v:
Genomics Data, Vol 12, Iss C, Pp 136-145 (2017)
Embryonic stem cells (mESCs), having potential to differentiate into three germ-layer cells including cardiomyocytes, shall be a perfect model to help understanding heart development. Here, using small RNA deep sequencing, we studied the small RNAome
Externí odkaz:
https://doaj.org/article/eed83a68d40e415a8232a9e919299507
Autor:
Xiao‐Xu Qiu, Yang Liu, Yi‐Fan Zhang, Ya‐Na Guan, Qian‐Qian Jia, Chen Wang, He Liang, Yong‐Qin Li, Huang‐Tian Yang, Yong‐Wen Qin, Shuang Huang, Xian‐Xian Zhao, Qing Jing
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 6, Iss 10 (2017)
BackgroundCardiomyocytes differentiated from human pluripotent stem cells can serve as an unexhausted source for a cellular cardiac disease model. Although small molecule–mediated cardiomyocyte differentiation methods have been established, the dif
Externí odkaz:
https://doaj.org/article/4e47152308b541ad9f58d4971609ea30
Publikováno v:
Stem Cells International, Vol 2017 (2017)
MicroRNAs (miRNAs) play important roles in cell fate decisions. However, the miRNAs and their targets involved in the regulation of cardiac lineage specification are largely unexplored. Here, we report novel functions of miR-142-3p in the regulation
Externí odkaz:
https://doaj.org/article/77914f4ed9b7468882309cfb6581bee7
Autor:
Wei Huang, Bo Dai, Zhili Wen, Ronald W Millard, Xi-Yong Yu, Kristin Luther, Meifeng Xu, Ting C Zhao, Huang-Tian Yang, Zhihua Qi, Kathleen Lasance, Muhammad Ashraf, Yigang Wang
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e70023 (2013)
OBJECTIVE:The purpose of this study was to assess the effect of collagen composition on engraftment of progenitor cells within infarcted myocardium. BACKGROUND:We previously reported that intramyocardial penetration of stem/progenitor cells in epicar
Externí odkaz:
https://doaj.org/article/a51dc0b082b14502802745f7084e9ec4
Autor:
An-Jing Ren, Chunchun Wei, Ya-Jin Liu, Mengna Liu, Ping Wang, Juan Fan, Kai Wang, Sha Zhang, Zhenbang Qin, Qiu-Xiao Ren, Yanjun Zheng, Yu-Xia Chen, Zhifang Xie, Ling Gao, Yi Zhu, Youyi Zhang, Huang-Tian Yang, Zhang, Weiping J.
Publikováno v:
Circulation Research; 2/2/2024, Vol. 134 Issue 3, p252-265, 14p