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of 287
pro vyhledávání: '"Huang, Dean"'
Autor:
Choi, H. James, Lo, Teresa W., Cutler, Kevin J., Huang, Dean, Will, W. Ryan, Wiggins, Paul A.
Protein expression levels optimize cell fitness: Too low an expression level of essential proteins will slow growth by compromising essential processes; whereas overexpression slows growth by increasing the metabolic load. This trade-off naively pred
Externí odkaz:
http://arxiv.org/abs/2408.11952
Koopman operator theory has found significant success in learning models of complex, real-world dynamical systems, enabling prediction and control. The greater interpretability and lower computational costs of these models, compared to traditional ma
Externí odkaz:
http://arxiv.org/abs/2311.12615
The processes of gene expression are inherently stochastic, even for essential genes required for growth. How does the cell maximize fitness in light of noise? To answer this question, we build a mathematical model to explore the trade-off between me
Externí odkaz:
http://arxiv.org/abs/2310.13803
The inherent stochasticity of cellular processes leads to significant cell-to-cell variation in protein abundance. Although this noise has already been characterized and modeled, its broader implications and significance remain unclear. In this paper
Externí odkaz:
http://arxiv.org/abs/2307.03324
An important step towards understanding the mechanistic basis of the central dogma is the quantitative characterization of the dynamics of nucleic-acid-bound molecular motors in the context of the living cell, where a crowded cytoplasm as well as com
Externí odkaz:
http://arxiv.org/abs/2208.06775
Autor:
Huang, Dean Y.1,2 (AUTHOR) dean.huang@nhs.net, Alsadiq, Majed3 (AUTHOR), Yusuf, Gibran T.1,2 (AUTHOR), Deganello, Annamaria1,2 (AUTHOR), Sellars, Maria E.1 (AUTHOR), Sidhu, Paul S.1,2 (AUTHOR)
Publikováno v:
Cancers. Jul2024, Vol. 16 Issue 13, p2309. 17p.
Publikováno v:
Phys. Rev. E 105, 014420 (2022)
Two powerful and complementary experimental approaches are commonly used to study the cell cycle and cell biology: One class of experiments characterizes the statistics (or demographics) of an unsynchronized exponentially-growing population, while th
Externí odkaz:
http://arxiv.org/abs/2108.10988
Autor:
Nguyen, Quynh M., Huang, Dean, Zauderer, Evan, Romanelli, Genevieve, Meyer, Charlotte L., Ristroph, Leif
Publikováno v:
American Journal of Physics 89.4 (2021): 393-402
Reasoning by analogy is powerful in physics for students and researchers alike, a case in point being electronics and hydraulics as analogous studies of electric currents and fluid flows. Around 100 years ago, Nikola Tesla proposed a flow control dev
Externí odkaz:
http://arxiv.org/abs/2103.14813
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Publikováno v:
In Manufacturing Letters August 2023 35 Supplement:342-349