Zobrazeno 1 - 10
of 153
pro vyhledávání: '"Huanchen Wang"'
Autor:
Xingyao Li, Regan B. Kirkpatrick, Xiaodong Wang, Charles J. Tucker, Anuj Shukla, Henning J. Jessen, Huanchen Wang, Stephen B. Shears, Chunfang Gu
Publikováno v:
Cell Reports, Vol 43, Iss 6, Pp 114316- (2024)
Summary: Phosphate (Pi) serves countless metabolic pathways and is involved in macromolecule synthesis, energy storage, cellular signaling, and bone maintenance. Herein, we describe the coordination of Pi uptake and efflux pathways to maintain mammal
Externí odkaz:
https://doaj.org/article/f3b6e793e06f4a21a4aaa698b4a545cf
Autor:
Huanchen Wang, Lalith Perera, Nikolaus Jork, Guangning Zong, Andrew M. Riley, Barry V. L. Potter, Henning J. Jessen, Stephen B. Shears
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
Inositol pyrophosphates (PP-IPs) regulate immunity and phosphate homeostasis. Here, the authors’ structural dissection of an Arabidopsis thaliana PP-IP phosphatase reveals that substrates drive their own hydrolysis and identifies a highly elusive m
Externí odkaz:
https://doaj.org/article/80727188fe0e4b42b9d3d714ec578029
Autor:
Stephen B. Shears, Huanchen Wang
Publikováno v:
Molecules, Vol 25, Iss 19, p 4515 (2020)
Inositol pyrophosphates (PP-InsPs) comprise an important group of intracellular, diffusible cellular signals that a wide range of biological processes throughout the yeast, plant, and animal kingdoms. It has been difficult to gain a molecular-level m
Externí odkaz:
https://doaj.org/article/cad11095833446aaa9c7da3183b9dd35
Autor:
Brandi M Baughman, Huanchen Wang, Yi An, Dmitri Kireev, Michael A Stashko, Henning J Jessen, Kenneth H Pearce, Stephen V Frye, Stephen B Shears
Publikováno v:
PLoS ONE, Vol 12, Iss 6, p e0180272 (2017)
Externí odkaz:
https://doaj.org/article/d01b745b9ec746979a07d77db60eb36a
Autor:
Brandi M Baughman, Huanchen Wang, Yi An, Dmitri Kireev, Michael A Stashko, Henning J Jessen, Kenneth H Pearce, Stephen V Frye, Stephen B Shears
Publikováno v:
PLoS ONE, Vol 11, Iss 10, p e0164378 (2016)
Pharmacological tools-'chemical probes'-that intervene in cell signaling cascades are important for complementing genetically-based experimental approaches. Probe development frequently begins with a high-throughput screen (HTS) of a chemical library
Externí odkaz:
https://doaj.org/article/7ed2fec04f874d708d7332f61fb59374
Publikováno v:
Issues in Information Systems, Vol 3, Pp 561-568 (2002)
Externí odkaz:
https://doaj.org/article/80a6da71186c459aaace0feeb1fb2959
Publikováno v:
Proceedings of the 2023 CHI Conference on Human Factors in Computing Systems.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2f0e67ff1581294d39a0be850f21eb47
https://doi.org/10.1145/3544548.3581476
https://doi.org/10.1145/3544548.3581476
Publikováno v:
International Conference on Computer Application and Information Security (ICCAIS 2022).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::664227970e7f830d61bf30cbfb8fe55b
https://doi.org/10.1117/12.2671691
https://doi.org/10.1117/12.2671691
Autor:
Yubai Zhou, Sandip Mukherjee, Daowei Huang, Molee Chakraborty, Chunfang Gu, Guangning Zong, Michael A. Stashko, Kenneth H. Pearce, Stephen B. Shears, Anutosh Chakraborty, Huanchen Wang, Xiaodong Wang
Publikováno v:
J Med Chem
Obesity and obesity-induced metabolic dysfunctions are significant risk factors for nonalcoholic fatty liver disease and cardiovascular diseases. Thus, obesity is an economic and social burden in developed countries. Blocking the synthesis of inosito
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd18436005877b78c4cc91e737f70a50
https://doi.org/10.1021/acs.jmedchem.2c00220
https://doi.org/10.1021/acs.jmedchem.2c00220
Publikováno v:
2022 IEEE International Conference on Big Data (Big Data).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d1c54fc3bdbe5737aedce445bfc927b5
https://doi.org/10.1109/bigdata55660.2022.10020763
https://doi.org/10.1109/bigdata55660.2022.10020763