Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Huan-Ling Lai"'
Autor:
Elaine Laihan Leung, Huan-Ling Lai, Run-Ze Li, Hu-Dan Pan, Ze-Bo Jiang, Ying Li, Fu-Gang Duan, Jia-Hui Xu, Yi-Zhong Zhang, A-Xi Shi, Chun-Li Wei, Fang-Yuan Zhang, Xiao-Jun Yao, Liang Liu
Publikováno v:
Engineering, Vol 10, Iss , Pp 174-182 (2022)
Secondary amyloid A amyloidosis, a lethal complication, is induced when acute or chronic infection coexists with over-secretion of the serum amyloid A 1 (SAA1) protein and deposition in key internal organs. Previously, using the whole-exome sequencin
Externí odkaz:
https://doaj.org/article/0d700a6845bc4acc9b16ca72efd91a47
Autor:
Ze-Bo Jiang, Ju-Min Huang, Ya-Jia Xie, Yi- Zhong Zhang, Chan Chang, Huan-Ling Lai, Wenjun Wang, Xiao-Jun Yao, Xing-Xing Fan, Qi-Biao Wu, Chun Xie, Mei-Fang Wang, Elaine Lai-Han Leung
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 39, Iss 1, Pp 1-16 (2020)
Abstract Background Accumulating evidence showed that regulating tumor microenvironment plays a vital role in improving antitumor efficiency. Programmed Death Ligand 1 (PD-L1) is expressed in many cancer cell types, while its binding partner Programm
Externí odkaz:
https://doaj.org/article/1d50b10fa1324da7958784d31a431d00
Autor:
Hudan Pan, Fang-Yuan Zhang, Elaine Lai-Han Leung, Jiahui Xu, Chunli Wei, Xiao-Jun Yao, Ze-Bo Jiang, A-Xi Shi, Yi-Zhong Zhang, Huan-Ling Lai, Fu-Gang Duan, Run-Ze Li, Ying Li, Liang Liu
Publikováno v:
Engineering. 10:174-182
Secondary amyloid A amyloidosis, a lethal complication, is induced when acute or chronic infection coexists with over-secretion of the serum amyloid A 1 (SAA1) protein and deposition in key internal organs. Previously, using the whole-exome sequencin
Autor:
Dan Li, Yuquan Liu, Hui You, Qibiao Wu, Imran Khan, Xiao-Jun Yao, Fu-Gang Duan, Run-Ze Li, Elaine Lai-Han Leung, Huan-Ling Lai, Yi-Zhong Zhang, Yabing Cao, Xing-Xing Fan, Meifang Wang, Wendy Wen-Lun Hsiao
Publikováno v:
Journal of Cancer Research and Clinical Oncology. 146:1441-1450
Poliovirus receptor (PVR) is a tumor promoter and a regulatory checkpoint that enhances immunosuppression. We investigated PVR expression by applying immunohistochemistry (IHC) staining. A positive association existed between PVR expression and cytot
Autor:
Fu-Gang Duan, Run-Ze Li, Meifang Wang, Liang Liu, Wendy Wen-Luan Hsiao, Qibiao Wu, Xing-Xing Fan, Elaine Lai-Han Leung, Yabing Cao, Huan-Ling Lai, Xiao-Jun Yao, Yijun Tang, Dan Li, Imran Khan, Yi-Zhong Zhang
Publikováno v:
Cell Death and Disease, Vol 10, Iss 11, Pp 1-14 (2019)
Cell Death & Disease
Cell Death & Disease
MicroRNAs regulate post-transcriptional gene expression and play important roles in multiple cellular processes. In this study, we found that miR-421 suppresses kelch-like ECH-associated protein 1(KEAP1) expression by targeting its 3′-untranslated
Autor:
Junmin Zhang, Yuwei Wang, Huan-Ling Lai, Run-Ze Li, Liang Liu, Xing-Xing Fan, Xiao-Jun Yao, Erwin Neher, Elaine Lai-Han Leung
Publikováno v:
Antioxidantsredox signaling. 34(14)
Recent Advances: The 2019 Nobel Prize awarded to the mechanisms for oxygen sensing and adaptation according to oxygen availability, highlighting the fundamental importance of gaseous molecules. Gaseous molecules, including reactive oxygen species (RO
Autor:
Liang Liu, Ze-Bo Jiang, A-Xi Shi, Ying Li, Fang-Yuan Zhang, Huan-Ling Lai, Fu-Gang Duan, Run-Ze Li, Xiaojun Yao, Jiahui Xu, Yi-Zhong Zhang, Elaine Lai-Han Leung, Chunli Wei, Hu-Dan Pan
Background: SAA1 in RA pathogenesis and its complications remains unknown, making early diagnosis and risk prevention difficult. This study is to determine the pathogenetic mechanisms of three different SAA1 protein isoforms in RA progression. Method
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e1e78d6ff69b9c7931b0ced48a70b3a
https://doi.org/10.21203/rs.2.22482/v2
https://doi.org/10.21203/rs.2.22482/v2
Autor:
Xiao-Jun Yao, Lin Wang, Wen-Jun Wang, Imran Khan, Jian-Lin Wu, Ya-Jia Xie, Yabing Cao, W.L. Wendy Hsiao, A-Xi Shi, Ze-Bo Jiang, Yuwei Wang, Qibiao Wu, Lian-Xiang Luo, Zhi-Hong Jiang, Jing-Guang Lu, Yu Fu, Hong Wei, Jun Cai, Elaine Lai-Han Leung, Di Liu, Ying Xie, Ju-Min Huang, Zhongqiu Liu, Haizhou Liu, Huan-Ling Lai, Jian Li, Ming-Rong Yang, Pei-Yu Yan, Liang Liu, Yi-Zhong Zhang, Xing-Xing Fan, Jing Yuan, Run-Ze Li, Junyi Liao
Publikováno v:
Gut. 71(4)
ObjectiveProgrammed death 1 and its ligand 1 (PD-1/PD-L1) immunotherapy is promising for late-stage lung cancer treatment, however, the response rate needs to be improved. Gut microbiota plays a crucial role in immunotherapy sensitisation and Panax g
Autor:
Liang Liu, Yi-Zhong Zhang, Elaine Lai-Han Leung, Fu-Gang Duan, Run-Ze Li, A-Xi Shi, Ying Li, Chunli Wei, Jiahui Xu, Ze-Bo Jiang, Fang-Yuan Zhang, Huan-Ling Lai, Hudan Pan, Xiao-Jun Yao
Publikováno v:
SSRN Electronic Journal.
Background: Secondary amyloid A amyloidosis, a lethal complication, is induced when acute or chronic infection coexisted with over-secretion of the SAA1 protein and deposition of SAA1 in key internal organs. Previously, using the whole-exome sequenci
Clinical significance of LSECtin and its association with PVR in non-small-cell lung cancer patients
Autor:
Meifang Wang, Peipei Chen, Elaine Lai-Han Leung, Dan Li, Qibiao Wu, Yi-Zhong Zhang, Huan-Ling Lai, Imran Khan, Xiao-Jun Yao, W.L. Wendy Hsiao, Xing-Xing Fan
Publikováno v:
Ann Transl Med
BACKGROUND: Liver and lymph node sinusoidal endothelial cell C-type lectin (LSECtin) is one of the new generation immune checkpoint ligand molecules and plays an important role in the immune environment. Poliovirus receptor (PVR), as another immunosu