Zobrazeno 1 - 10
of 520
pro vyhledávání: '"Huan Xiao"'
Publikováno v:
RNA Biology, Vol 20, Iss 1, Pp 384-397 (2023)
In the past two decades, machine learning (ML) has been extensively adopted in protein-targeted small molecule (SM) discovery. Once trained, ML models could exert their predicting abilities on large volumes of molecules within a short time. However,
Externí odkaz:
https://doaj.org/article/8bf420555e5f4118ad24c77875109cfd
Publikováno v:
Frontiers in Nutrition, Vol 11 (2024)
BackgroundThe agreement on the identification of sarcopenic obesity remains elusive, and its association with hyperuricemia remains unestablished. This study sought to evaluate the agreement of low lean mass (LLM) with obesity and its correlation wit
Externí odkaz:
https://doaj.org/article/e17ec671791d431eadefeb577e13ffa2
Autor:
Amu Gubu, Yuan Ma, Sifan Yu, Huarui Zhang, Zefeng Chen, Shuaijian Ni, Razack Abdullah, Huan Xiao, Yihao Zhang, Hong Dai, Hang Luo, Yuanyuan Yu, Luyao Wang, Hewen Jiang, Ning Zhang, Yuan Tian, Haitian Li, Aiping Lu, Baoting Zhang, Ge Zhang
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 35, Iss 1, Pp 102146- (2024)
Osteogenesis imperfecta (OI) is a rare genetic disease characterized by bone fragility and bone formation. Sclerostin could negatively regulate bone formation by antagonizing the Wnt signal pathway, whereas it imposes severe cardiac ischemic events i
Externí odkaz:
https://doaj.org/article/b6892e8f6fee4f7bb088fbb3ea09388b
Autor:
Yucong Lin, Jia Li, Huan Xiao, Lujie Zheng, Ying Xiao, Hong Song, Jingfan Fan, Deqiang Xiao, Danni Ai, Tianyu Fu, Feifei Wang, Han Lv, Jian Yang
Publikováno v:
BMC Medical Informatics and Decision Making, Vol 23, Iss 1, Pp 1-12 (2023)
Abstract Background Clinical practice guidelines (CPGs) are designed to assist doctors in clinical decision making. High-quality research articles are important for the development of good CPGs. Commonly used manual screening processes are time-consu
Externí odkaz:
https://doaj.org/article/942a8d5371554399be117422f021e5d6
Autor:
Hong-Quan Xu, Huan Xiao, Jin-Hui Bu, Yan-Feng Hong, Yu-Hong Liu, Zi-Yue Tao, Shu-Fan Ding, Yi-Tong Xia, E Wu, Zhen Yan, Wei Zhang, Gong-Xing Chen, Feng Zhu, Lin Tao
Publikováno v:
Journal of Cheminformatics, Vol 15, Iss 1, Pp 1-10 (2023)
Abstract The discovery and utilization of natural products derived from endophytic microorganisms have garnered significant attention in pharmaceutical research. While remarkable progress has been made in this field each year, the absence of dedicate
Externí odkaz:
https://doaj.org/article/6c3d2ab7ece64f58ba0451d238d17536
Publikováno v:
BMC Musculoskeletal Disorders, Vol 24, Iss 1, Pp 1-11 (2023)
Abstract Background Oxidative stress was closely related to the occurrence and development of Steroid-induced osteonecrosis of the femoral head (SIONFH). 8-hydroxy-2'-deoxyguanosine (8-OHdG) is a important index of oxidative stress. The aim of this s
Externí odkaz:
https://doaj.org/article/29783647568f4d12a0a9391b6a2265e1
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 13, Iss 10, Pp 4060-4088 (2023)
Protein–protein interactions (PPIs) are fundamental to many biological processes that play an important role in the occurrence and development of a variety of diseases. Targeting the interaction between tumour-related proteins with emerging small m
Externí odkaz:
https://doaj.org/article/2ab4098f94114f459276258cbbf35a3a
Publikováno v:
Journal of Orthopaedic Surgery and Research, Vol 18, Iss 1, Pp 1-11 (2023)
Abstract Background Osteonecrosis of the femoral head (ONFH) is becoming a prevalent global health problem. 4-Hydroxynonenal (4-HNE) serves as a common marker of oxidative stress. This study aims to study the potential role of 4-HNE in the progressio
Externí odkaz:
https://doaj.org/article/52dd2841a81c486cbeb71c026b9a9a67
Publikováno v:
Aerospace, Vol 11, Iss 7, p 552 (2024)
The residual stress field induced by interference-fit riveting in aircraft panel structures significantly affects the fatigue performance around the rivet holes. Common residual stress analytical models often overlook the non-uniformity of interferen
Externí odkaz:
https://doaj.org/article/427644bbcca04f2e9cee80b761b21a9e
Publikováno v:
PLoS ONE, Vol 19, Iss 4 (2024)
Externí odkaz:
https://doaj.org/article/ac325dca0e26440886ea37ecf4a52525