Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Huan Xiajuan"'
Autor:
Luo, Menglan, Wu, Qian, Yang, Yueyue, Sun, Lin, Huan, Xiajuan, Tian, Changqing, Xiong, Bing, Miao, Zehong, Wang, Yingqing, Chen, Danqi
Publikováno v:
In European Journal of Medicinal Chemistry 5 September 2022 239
Autor:
Chen, Xuxing, Huan, Xiajuan, Liu, Qiufeng, Wang, Yuqin, He, Qian, Tan, Cun, Chen, Yi, Ding, Jian, Xu, Yechun, Miao, Zehong, Yang, Chunhao
Publikováno v:
In European Journal of Medicinal Chemistry 10 February 2018 145:389-403
Autor:
Chen, Wenhua, Guo, Ne, Qi, Minghui, Dai, Haiying, Hong, Minghuang, Guan, Longfei, Huan, Xiajuan, Song, Shanshan, He, Jinxue, Wang, Yingqing, Xi, Yong, Yang, Xinying, Shen, Yanyan, Su, Yi, Sun, Yiming, Gao, Yinglei, Chen, Yi, Ding, Jian, Tang, Yun, Ren, Guobin, Miao, Zehong, Li, Jian
Publikováno v:
In European Journal of Medicinal Chemistry 29 September 2017 138:514-531
Autor:
Min Yang, Xiao-Ming Wang, Yue-Wei Guo, Song-Wei Li, Huan Xiajuan, Ze-Hong Miao, Yi Chen, Fang-Zhou Yin
Publikováno v:
Natural Products and Bioprospecting
Natural Products and Bioprospecting, Vol 11, Iss 1, Pp 73-79 (2020)
Natural Products and Bioprospecting, Vol 11, Iss 1, Pp 73-79 (2020)
Abstract A phytochemical investigation of the EtOH extract of the flowers of Lagerstroemia indica L. led to the isolation and characterization of a new pyrrole alkaloid, named lagerindicine (1), along with four known compounds (2–5). Their structur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adb72f6e8a0c432b1a4be2bc28010159
https://doi.org/10.1007/s13659-020-00273-x
https://doi.org/10.1007/s13659-020-00273-x
Autor:
Chang-Qing Tian, Ying-Qing Wang, Jianping Hu, Danqi Chen, Huan Xiajuan, Shanshan Song, Ze-Hong Miao, Bing Xiong, Tao Meng, Mohammadali Soleimani Damaneh, Jingkang Shen, Yue-Lei Chen
Publikováno v:
Investigational New Drugs. 38:700-713
The bromodomain and extra-terminal domain (BET) family of proteins, especially bromodomain-containing protein 4 (BRD4), has emerged as exciting anti-tumor targets due to their important roles in epigenetic regulation. Therefore, the discovery of BET
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3138f32200f3dfd224627e4942e06b9a
https://doi.org/10.1007/s10637-019-00818-z
https://doi.org/10.1007/s10637-019-00818-z
Autor:
Ze-Hong Miao, Hua-Dong Chen, Lin Chen, Bing Xiong, Jianping Hu, Chang-Qing Tian, Huan Xiajuan, Ying-Qing Wang, Jingkang Shen
Publikováno v:
Cell Death and Disease, Vol 10, Iss 8, Pp 1-13 (2019)
Cell Death & Disease
Cell Death & Disease
The bromodomain and extra terminal domain (BET) family members, including BRD2, BRD3, and BRD4, act as epigenetic readers to regulate gene expression. Indoleamine 2,3-dioxygenase 1 (IDO1) is an enzyme that participates in tumor immune escape primaril
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a8e1400201c579037c4840db413849f
http://link.springer.com/article/10.1038/s41419-019-1793-9
http://link.springer.com/article/10.1038/s41419-019-1793-9
Autor:
Chuan-Huizi Chen, Hua-Dong Chen, Shanshan Song, Jin-Xue He, Ze-Hong Miao, Huan Xiajuan, Ne Guo, Yu-Nan Tian, Yu-Ting Wang
Publikováno v:
International Journal of Cancer. 145:714-727
PARP1 inhibitors (PARPis) are used clinically during cancer therapy and are thought to exert their cytotoxicity through PARP1 polymerase inhibition and PARP1-DNA trapping. Here, we showed no significant correlation between PARP1-DNA trapping and cyto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1d3e6b4d4f9b879c84535787c95d79f5
https://doi.org/10.1002/ijc.32131
https://doi.org/10.1002/ijc.32131
Autor:
Yang, Bowen, Wu, Qian, Huan, Xiajuan, Wang, Yingqing, Sun, Yin, Yang, Yueyue, Liu, Tongchao, Wang, Xin, Chen, Lin, Xiong, Bing, Zhao, Dongmei, Miao, Zehong, Chen, Danqi
Publikováno v:
In Bioorganic & Medicinal Chemistry Letters 1 February 2021 33
Autor:
Hua-Dong Chen, Jin-Xue He, Xu-Bin Bao, Meng-Zhu Li, Huan Xiajuan, Ze-Hong Miao, Ning Zhang, Ao Zhang, Yu-Nan Tian, Li-Na Zhou, Shanshan Song
Publikováno v:
Cell Death & Disease
Cell Death and Disease, Vol 12, Iss 2, Pp 1-18 (2021)
Cell Death and Disease, Vol 12, Iss 2, Pp 1-18 (2021)
Monotherapy with poly ADP-ribose polymerase (PARP) inhibitors results in a limited objective response rate (≤60% in most cases) in patients with homologous recombination repair (HRR)-deficient cancer, which suggests a high rate of resistance in thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7efb8d21c6a0cf7895bf49ad4b74dc88
https://doi.org/10.1038/s41419-021-03475-4
https://doi.org/10.1038/s41419-021-03475-4
Autor:
Xu-Bing Bao, Ning Zhang, He Jinxue, Miao Zehong, Ao Zhang, Song Shanshan, Li-Na Zhou, Meng-Zhu Li, Yu-Nan Tian, Huan Xiajuan
Background: Monotherapy with poly ADP-ribose polymerase (PARP) inhibitors results in limited objective response rate (≤ 60% in most cases) in patients with homologous recombination repair (HRR)-deficient cancer, which suggests a high rate of resist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::08f98ccd62dfe07c585fc94e96b01487
https://doi.org/10.21203/rs.3.rs-48785/v1
https://doi.org/10.21203/rs.3.rs-48785/v1
