Zobrazeno 1 - 10
of 188
pro vyhledávání: '"Huan Rui"'
Autor:
Ryan P. Wurz, Huan Rui, Ken Dellamaggiore, Sudipa Ghimire-Rijal, Kaylee Choi, Kate Smither, Albert Amegadzie, Ning Chen, Xiaofen Li, Abhisek Banerjee, Qing Chen, Dane Mohl, Amit Vaish
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract Targeted protein degradation via “hijacking” of the ubiquitin-proteasome system using proteolysis targeting chimeras (PROTACs) has evolved into a novel therapeutic modality. The design of PROTACs is challenging; multiple steps involved i
Externí odkaz:
https://doaj.org/article/de7e722d28104330ab18533bf9830472
Publikováno v:
Annals of Medicine, Vol 55, Iss 1 (2023)
AbstractBackground Dietary fibre and cognitive function are associated with the risk of mortality, respectively. Inadequate dietary fibre intake and cognitive impairment frequently co-occur in older adults, but the combined effect of dietary fibre an
Externí odkaz:
https://doaj.org/article/6bf47ad6daf4401c89a5a70b3757fc67
Publikováno v:
Data in Brief, Vol 32, Iss , Pp 106135- (2020)
Barium is a potent blocker of the KcsA potassium channel. A strategy using x-ray crystallography and molecular dynamics (MD) simulation has been used to understand this phenomenon as described in Rohaim et al. [1]. Wild type KcsA is purified to homog
Externí odkaz:
https://doaj.org/article/a9f7cf448b0543e2bdd1bd11dbfe829b
Autor:
Yue Hao, Whitney E Purtha, Christa Cortesio, Huan Rui, Yan Gu, Hao Chen, E Allen Sickmier, Paolo S Manzanillo, Xin Huang
Publikováno v:
PLoS ONE, Vol 14, Iss 6, p e0218063 (2019)
[This corrects the article DOI: 10.1371/journal.pone.0200374.].
Externí odkaz:
https://doaj.org/article/34fad8c3366b45b7b5552fa19e5be426
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
Tetrameric cationic channels specificity is determined by the sequence and structural conformation of their selectivity filter. Here, the authors show that a cationic channel from Tsukamurella paurometabola is non-selective due to a Ca2+-binding moti
Externí odkaz:
https://doaj.org/article/54ddb1f1acfa493bbfb0cb50effbba4f
Autor:
Yue Hao, Whitney Purtha, Christa Cortesio, Huan Rui, Yan Gu, Hao Chen, E Allen Sickmier, Paolo Manzanillo, Xin Huang
Publikováno v:
PLoS ONE, Vol 13, Iss 7, p e0200374 (2018)
Cathepsin H is a member of the papain superfamily of lysosomal cysteine proteases. It is the only known aminopeptidase in the family and is reported to be involved in cancer and other major diseases. Like many other proteases, it is synthesized as an
Externí odkaz:
https://doaj.org/article/bc889651b61041d4af51369ee8d2fabc
Autor:
Ramokapane, Kopo M., Coles-Kemp, Lizzie, Patnaik, Nikhil, Huan, Rui, Ajmeri, Nirav, Liveley, Genevieve, Rashid, Awais
Ensuring equitable privacy experiences remains a challenge, especially for marginalised and vulnerable populations (MVPs) who often hesitate to participate or use digital services due to concerns about the privacy of their sensitive information. In r
Externí odkaz:
http://arxiv.org/abs/2308.00004
Publikováno v:
eLife, Vol 5 (2016)
The Na+/K+-pump maintains the physiological K+ and Na+ electrochemical gradients across the cell membrane. It operates via an 'alternating-access' mechanism, making iterative transitions between inward-facing (E1) and outward-facing (E2) conformation
Externí odkaz:
https://doaj.org/article/5e19ee2ce6484533b9e5acc610af408e
Publikováno v:
Food & Function; 6/7/2024, Vol. 15 Issue 11, p6164-6173, 10p
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