Zobrazeno 1 - 10
of 645
pro vyhledávání: '"Huan Fang"'
Publikováno v:
Synthetic and Systems Biotechnology, Vol 9, Iss 3, Pp 513-521 (2024)
Genetically encoded circuits have been successfully utilized to assess and characterize target variants with desirable traits from large mutant libraries. Adenosylcobalamin is an essential coenzyme that is required in many intracellular physiological
Externí odkaz:
https://doaj.org/article/e15f5c3e342a432ca5d14584dc21f9f9
Autor:
Feitao Chen, Huan Fang, Jianghua Zhao, Pingtao Jiang, Huina Dong, Ying Zhao, Huiying Wang, Tongcun Zhang, Dawei Zhang
Publikováno v:
Synthetic and Systems Biotechnology, Vol 9, Iss 3, Pp 453-461 (2024)
Vitamin B12 is a complex compound synthesized by microorganisms. The industrial production of vitamin B12 relies on specific microbial fermentation processes. E. coli has been utilized as a host for the de novo biosynthesis of vitamin B12, incorporat
Externí odkaz:
https://doaj.org/article/a721a38d0fdf40d1b79f2665401a8f6b
Publikováno v:
Microbial Cell Factories, Vol 23, Iss 1, Pp 1-13 (2024)
Abstract Background Bacillus subtilis is widely used in industrial-scale riboflavin production. Previous studies have shown that targeted mutagenesis of the ribulose 5-phosphate 3-epimerase in B. subtilis can significantly enhance riboflavin producti
Externí odkaz:
https://doaj.org/article/66f8c85b589f4a03b4923890a0f6bdb8
Publikováno v:
Microbial Cell Factories, Vol 23, Iss 1, Pp 1-14 (2024)
Abstract Biotin, serving as a coenzyme in carboxylation reactions, is a vital nutrient crucial for the natural growth, development, and overall well-being of both humans and animals. Consequently, biotin is widely utilized in various industries, incl
Externí odkaz:
https://doaj.org/article/c71c11d24ae34e9ba128e2c88ab56b77
Publikováno v:
Applied Artificial Intelligence, Vol 38, Iss 1 (2024)
ABSTRACTThe effectiveness of business process analysis heavily relies on the quality of event logs. However, the presence of outliers and missing values often compromises the integrity of event logs, consequently exerting adverse effects on process a
Externí odkaz:
https://doaj.org/article/9493f2b7e03c400c9c4de436c8f8dd3f
Autor:
Mingxin Sang, Nan Pan, Jingna Wu, Xiaoting Chen, Shuilin Cai, Huan Fang, Meitian Xiao, Xiaoming Jiang, Zhiyu Liu
Publikováno v:
Marine Drugs, Vol 22, Iss 6, p 285 (2024)
Omega-3 fatty acids are in high demand due to their efficacy in treating hypertriglyceridemia and preventing cardiovascular diseases. However, the growth of the industry is hampered by low purity and insufficient productivity. This study aims to deve
Externí odkaz:
https://doaj.org/article/0c7b4cf993cd4bf799465b916b300b4c
Autor:
Qian Kang, Huan Fang, Mengjie Xiang, Kaixing Xiao, Pingtao Jiang, Chun You, Sang Yup Lee, Dawei Zhang
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Adenosylcobalamin (AdoCbl), a biologically active form of vitamin B12 (coenzyme B12), is one of the most complex metal-containing natural compounds and an essential vitamin for animals. However, AdoCbl can only be de novo synthesized by prok
Externí odkaz:
https://doaj.org/article/2a9304de076142edb92a158bbee21213
Autor:
Huan Fang, Wenlong Ren, Qiuxia Cui, Huichun Liang, Chuanyu Yang, Wenjing Liu, Xinye Wang, Xue Liu, Yujie Shi, Jing Feng, Ceshi Chen
Publikováno v:
eLife, Vol 12 (2023)
Anti-tumor drug resistance is a challenge for human triple-negative breast cancer (TNBC) treatment. Our previous work demonstrated that TNFAIP2 activates RAC1 to promote TNBC cell proliferation and migration. However, the mechanism by which TNFAIP2 a
Externí odkaz:
https://doaj.org/article/a47e4ac1b011411da2906874af50c308
Publikováno v:
IEEE Access, Vol 11, Pp 133160-133173 (2023)
Event logs of business processes provide a valuable starting point for process mining, and high-quality event logs can significantly enhance the quality of process mining. However, event logs often contain a substantial amount of sensitive and person
Externí odkaz:
https://doaj.org/article/5a92d487b68a4312911e9db57e625a1a
Publikováno v:
IEEE Access, Vol 11, Pp 64815-64830 (2023)
It is a fact that plenty of process variants are derived from the same base model in practical applications, and the main reasons include inevitable software maintenance and adaptability of process models. This fact raises a question that many proces
Externí odkaz:
https://doaj.org/article/e2e97c94308948b18bfd321467196de7