Zobrazeno 1 - 10
of 92
pro vyhledávání: '"Huaming, Sheng"'
Publikováno v:
Analytical Chemistry. 94:7928-7935
Sulfonate esters, a class of potentially mutagenic drug impurities, are strictly regulated in pharmaceuticals. On the other hand, sulfite esters and sulfones, analogs of sulfonate esters, have limited safety concerns. However, previously developed an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36d2110c3b4d2061bff241972a7b597d
https://doi.org/10.1021/acs.analchem.2c00731
https://doi.org/10.1021/acs.analchem.2c00731
Publikováno v:
Biomedical Reports. Jan2021, Vol. 14 Issue 1, p1-7. 7p.
Autor:
Richard Meilan, Lan Xu, Hilkka I. Kenttämaa, W. Nicholas Delgass, Abhijit Talpade, Rakesh Agrawal, Priya Murria, Fabio H. Ribeiro, Huaming Sheng, Xin Ma, Clint Chapple
Publikováno v:
Journal of the American Society for Mass Spectrometry. 32:2546-2551
The proportional content of the phenylpropanoid monomeric units (4-hydroxyphenyl (H), guaiacyl (G), and syringyl (S)) in lignin is of paramount importance in germ plasm screening and for evaluating the results of plant breeding and genetic engineerin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4467d60f9e5f283d14fc8618057e0b71
https://doi.org/10.1021/jasms.1c00186
https://doi.org/10.1021/jasms.1c00186
Autor:
Judy Kuan-Yu Liu, Erlu Feng, Yue Fu, Wanru Li, Xin Ma, Huaming Sheng, John Kong, Yong Liu, Michael Hicks, Bangping Xiang, Zhijian Liu, Justin Pennington, Hilkka I. Kenttämaa
Publikováno v:
Analytical chemistry. 94(40)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c674c53e4e3c6f82d91cae5fe222424
https://pubmed.ncbi.nlm.nih.gov/36154017
https://pubmed.ncbi.nlm.nih.gov/36154017
Autor:
Huaming Sheng, Victoria Ordsmith, Emily B. Corcoran, Ping Zhuang, Simon E. Hamilton, Zachary E. X. Dance, Zhihao Lin, Joseph P. Smith
Publikováno v:
Organic Process Research & Development. 24:2611-2618
Online mass spectrometry has proven to be a useful tool for characterizing many aspects of chemical reactions. However, to the best of the authors’ knowledge, no reference standard (RS) quantitatio...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e84a919276c3fcffe6e89dbd6922fa69
https://doi.org/10.1021/acs.oprd.0c00294
https://doi.org/10.1021/acs.oprd.0c00294
Autor:
Erlu Feng, Wanru Li, Jifa Zhang, John J. Nash, Hilkka I. Kenttämaa, Jacob Milton, Leah F. Easterling, Huaming Sheng
Publikováno v:
Analytical Chemistry. 92:11895-11903
Unlabeled and deuterium-labeled dimeric lignin model compounds with β-O-4 linkages were evaporated and ionized using negative ion mode electrospray ionization, transferred into a linear quadrupole ion trap, isolated, and subjected to collision-activ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2e3432c42a2c6cb7cc6634cba9ce8f1
https://doi.org/10.1021/acs.analchem.0c02275
https://doi.org/10.1021/acs.analchem.0c02275
Autor:
Lan, Xu, Xin, Ma, Priya, Murria, Abhijit, Talpade, Huaming, Sheng, Richard, Meilan, Clint, Chapple, Rakesh, Agrawal, W Nicholas, Delgass, Fabio H, Ribeiro, Hilkka I, Kenttämaa
Publikováno v:
Journal of the American Society for Mass Spectrometry. 32(10)
The proportional content of the phenylpropanoid monomeric units (4-hydroxyphenyl (H), guaiacyl (G), and syringyl (S)) in lignin is of paramount importance in germ plasm screening and for evaluating the results of plant breeding and genetic engineerin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e418fce7d28914a66279f149f1013729
https://pubmed.ncbi.nlm.nih.gov/34463497
https://pubmed.ncbi.nlm.nih.gov/34463497
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 174:235-241
2-(dichloromethyl)-5[4-(methylsulfonyl)-phenyl]-4-(fluoromethyl)-oxazoline (DFC-M, 1) is a key oxazoline-containing intermediate in commercial process for the synthesis of Florfenicol (3), a marketed broad spectrum veterinary antibiotic. DFC-M was no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f68b5ee4ce9ae52cfcc04f42f6492321
https://doi.org/10.1016/j.jpba.2019.05.009
https://doi.org/10.1016/j.jpba.2019.05.009
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 174:242-247
Ceftolozane is MSD's 5th generation cephalosporin antibiotic with broad-spectrum gram-negative activity. While refining the synthetic route to the drug substance, a dimeric impurity was observed in the final active pharmaceutical ingredient (API) of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4271fb50e04027681f51f7c6c56967a
https://doi.org/10.1016/j.jpba.2019.05.057
https://doi.org/10.1016/j.jpba.2019.05.057
Autor:
Hilkka I. Kenttämaa, Edouard Niyonsaba, John Kong, Leah F. Easterling, Mckay W Easton, Zhoupeng Zhang, Harry R. Chobanian, Gozdem Kilaz, Huaming Sheng, Erlu Feng, Nicholas R. Deprez, Zaikuan Yu, Jacob Milton, Mark T. Cancilla
Publikováno v:
Analytical Chemistry. 91:11388-11396
Glucuronidation, a common phase II biotransformation reaction, is one of the major in vitro and in vivo metabolism pathways of xenobiotics. In this process, glucuronic acid is conjugated to a drug ...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f26900fb10ea9b3dbe41b0cf02ebfb6b
https://doi.org/10.1021/acs.analchem.9b02717
https://doi.org/10.1021/acs.analchem.9b02717