Zobrazeno 1 - 10
of 1 017
pro vyhledávání: '"Huamin Wang"'
Autor:
Jie Fu, Jianhua Ling, Ching-Fei Li, Chi-Lin Tsai, Wenjuan Yin, Junwei Hou, Ping Chen, Yu Cao, Ya’an Kang, Yichen Sun, Xianghou Xia, Zhou Jiang, Kenei Furukawa, Yu Lu, Min Wu, Qian Huang, Jun Yao, David H. Hawke, Bih-Fang Pan, Jun Zhao, Jiaxing Huang, Huamin Wang, E. I. Mustapha Bahassi, Peter J. Stambrook, Peng Huang, Jason B. Fleming, Anirban Maitra, John A. Tainer, Mien-Chie Hung, Chunru Lin, Paul J. Chiao
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Pancreatic ductal adenocarcinoma (PDAC) develops through step-wise genetic and molecular alterations including Kras mutation and inactivation of various apoptotic pathways. Here, we find that development of apoptotic resistance and metastasi
Externí odkaz:
https://doaj.org/article/c655bcead33042daab28080db2e56eaa
Autor:
Abdelrahman Yousef, Mahmoud Yousef, Saikat Chowdhury, Kawther Abdilleh, Mark Knafl, Paul Edelkamp, Kristin Alfaro-Munoz, Ray Chacko, Jennifer Peterson, Brandon G. Smaglo, Robert A. Wolff, Shubham Pant, Michael S. Lee, Jason Willis, Michael Overman, Sudheer Doss, Lynn Matrisian, Mark W. Hurd, Rebecca Snyder, Matthew H. G. Katz, Huamin Wang, Anirban Maitra, John Paul Shen, Dan Zhao
Publikováno v:
npj Precision Oncology, Vol 8, Iss 1, Pp 1-13 (2024)
Abstract The relevance of KRAS mutation alleles to clinical outcome remains inconclusive in pancreatic adenocarcinoma (PDAC). We conducted a retrospective study of 803 patients with PDAC (42% with metastatic disease) at MD Anderson Cancer Center. Ove
Externí odkaz:
https://doaj.org/article/07e4c9e5f98d41abaef00dd9155ae1ad
Autor:
Yi Xu, Michael H. Nipper, Angel A. Dominguez, Zhenqing Ye, Naoki Akanuma, Kevin Lopez, Janice J. Deng, Destiny Arenas, Ava Sanchez, Francis E. Sharkey, Colin M. Court, Aatur D. Singhi, Huamin Wang, Martin E. Fernandez-Zapico, Lu-Zhe Sun, Siyuan Zheng, Yidong Chen, Jun Liu, Pei Wang
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Animal studies have demonstrated the ability of pancreatic acinar cells to transform into pancreatic ductal adenocarcinoma (PDAC). However, the tumorigenic potential of human pancreatic acinar cells remains under debate. To address this gap
Externí odkaz:
https://doaj.org/article/3ae4e657182c429c839f4021884860ba
Autor:
Hanxiao Li, Yingyue Dong, Chunmiao Han, Lisha Xia, Yue Zhang, Tongsheng Chen, Huamin Wang, Guoheng Xu
Publikováno v:
Lipids in Health and Disease, Vol 22, Iss 1, Pp 1-16 (2023)
Abstract Background Previous studies demonstrated that mast cells with their degranulated component heparin are the major endogenous factors that stimulate preadipocyte differentiation and promote fascial adipogenesis, and this effect is related to t
Externí odkaz:
https://doaj.org/article/5a8f19c5ad8d44868400bbe9464abd91
Autor:
Yuhui Zeng, Xicheng Tan, Moquan Sha, Zeenat Khadim Hussain, Tongliang Lin, Jianguang Tu, Huamin Wang, Bocai Liu, Chaopeng Li, Fang Huang, Zongyao Sha
Publikováno v:
International Journal of Applied Earth Observations and Geoinformation, Vol 128, Iss , Pp 103708- (2024)
In situations where natural disasters damage public communication networks, self-organized emergency communication networks play a vital role as important resources for disaster monitoring and emergency response. Geographical conditions, communicatio
Externí odkaz:
https://doaj.org/article/7922bd7ac1994ebdadf315115bb0740c
Autor:
Dongshi Liang, Meiqian Yu, Shuaishuai Huang, Jinglin Wang, Zijin Xu, Daai Li, Zhongyu Li, Huamin Wang
Publikováno v:
Materials & Design, Vol 235, Iss , Pp 112456- (2023)
Magnolol shows promise as an effective anti-tumor therapeutic agent. Nevertheless, the clinical application of this agent is constrained by its inherent water insolubility and diminished stability. In the present investigation, we have developed a ne
Externí odkaz:
https://doaj.org/article/e73dfc7b58884ceca619cea7071e55d2
Publikováno v:
Green Synthesis and Catalysis, Vol 4, Iss 1, Pp 54-57 (2023)
A highly efficient and mild method for [3 + 2] cycloaddition of β-sulfonyl-α,β-unsaturated ketones with terminal allenoates was well-explored and developed. The reactions were successfully performed by applying multifunctional chiral phosphi
Externí odkaz:
https://doaj.org/article/59c20e72f65f4f4d91eadadd2668e328
Autor:
Hua Wang, Rohan Moniruzzaman, Lei Li, Baoan Ji, Yi Liu, Xiangsheng Zuo, Reza Abbasgholizadeh, Jun Zhao, Guangchao Liu, Ruiqi Wang, Hongli Tang, Ryan Sun, Xiaoping Su, Tse-Hua Tan, Anirban Maitra, Huamin Wang
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 12 (2023)
Ras plays an essential role in the development of acinar-to-ductal metaplasia (ADM) and pancreatic ductal adenocarcinoma (PDAC). However, mutant Kras is an inefficient driver for PDAC development. The mechanisms of the switching from low Ras activity
Externí odkaz:
https://doaj.org/article/387208fdd37b4d7fa8c9d084ec53be4a
Autor:
Ying Lu, Wenhao Li, Yalin Li, Wanying Zhai, Xuming Zhou, Zhichao Wu, Shouwen Jiang, Taigang Liu, Huamin Wang, Ruiqin Hu, Yan Zhou, Jun Zou, Peng Hu, Guijun Guan, Qianghua Xu, Adelino V. M. Canário, Liangbiao Chen
Publikováno v:
BMC Biology, Vol 20, Iss 1, Pp 1-20 (2022)
Abstract Background Antarctica harbors the bulk of the species diversity of the dominant teleost fish suborder—Notothenioidei. However, the forces that shape their evolution are still under debate. Results We sequenced the genome of an icefish, Chi
Externí odkaz:
https://doaj.org/article/d40c2200b8254c7692b93bf700ec2acf
Autor:
Christophe Glorieux, Xiaojun Xia, Xin You, Zining Wang, Yi Han, Jing Yang, Gauthier Noppe, Christophe de Meester, Jianhua Ling, Annie Robert, Hui Zhang, Sheng-Ping Li, Huamin Wang, Paul J. Chiao, Li Zhang, Xiaobing Li, Peng Huang
Publikováno v:
Journal of Advanced Research, Vol 40, Iss , Pp 109-124 (2022)
Introduction: Immunochemotherapy using PD-1/PD-L1 antibodies in combination with chemotherapeutic agents has become a mainstream treatment for cancer patients, but it remains unclear which drug combinations would produce best therapeutic outcome. Obj
Externí odkaz:
https://doaj.org/article/31e4ae69c8a84d92ae62b9fc4d2e23ad