Zobrazeno 1 - 10
of 158
pro vyhledávání: '"Huamei, Tang"'
Autor:
Xiaole Meng, Risi Na, Xiao Peng, Hui Li, Wanxin Ouyang, Wenting Zhou, Xuting You, Yuhuan Li, Xin Pu, Ke Zhang, Junjie Xia, Jie Wang, Huamei Tang, Guohong Zhuang, Zhihai Peng
Publikováno v:
Cell Communication and Signaling, Vol 22, Iss 1, Pp 1-24 (2024)
Abstract Post-translational modifications (PTMs) of the non-histone protein high-mobility group protein B1 (HMGB1) are involved in modulating inflammation and immune responses. Recent studies have implicated that the RNA-binding protein (RBP) Musashi
Externí odkaz:
https://doaj.org/article/ea1da2c16f25456d9ab05c03cce9a716
Autor:
Xiaole Meng, Xiao Peng, Wanxin Ouyang, Hui Li, Risi Na, Wenting Zhou, Xuting You, Yuhuan Li, Xin Pu, Ke Zhang, Junjie Xia, Jie Wang, Guohong Zhuang, Huamei Tang, Zhihai Peng
Publikováno v:
Biological Procedures Online, Vol 25, Iss 1, Pp 1-23 (2023)
Abstract Background Musashi-2 (MSI2) is a critical RNA-binding protein (RBP) whose ectopic expression drives the pathogenesis of various cancers. Accumulating evidence suggests that inducing ferroptosis of tumor cells can inhibit their malignant biol
Externí odkaz:
https://doaj.org/article/aa2da4cd9ab64a2baf8d883cbed102f9
Publikováno v:
BMC Genomics, Vol 24, Iss 1, Pp 1-13 (2023)
Abstract Background Copy number variation (CNV) is a type of structural variation, which is a gain or loss event with abnormal changes in copy number. Methods to predict the pathogenicity of CNVs are required to realize the relationship between these
Externí odkaz:
https://doaj.org/article/31aeb4672ae343bb83a18f5557a52138
Autor:
Nengneng Li, Shiquan Xu, Shuaishuai Zhang, Qiang Zhu, Xiaole Meng, Wenbin An, Baoqing Fu, Mengya Zhong, Yan Yang, Zeyang Lin, Xueni Liu, Junjie Xia, Jie Wang, Tingting You, Changxiu Yan, Huamei Tang, Guohong Zhuang, Zhihai Peng
Publikováno v:
Frontiers in Immunology, Vol 13 (2023)
BackgroundThe etiology and pathogenesis of inflammatory bowel disease (IBD), including ulcerative colitis (UC) and Crohn’s disease (CD), are generally believed to be related to immune dysfunction and intestinal microbiota disorder. However, the exa
Externí odkaz:
https://doaj.org/article/1ff619ce14ff43479efe5c5886839dea
Autor:
Yan Yang, Zeyang Lin, Zhaopu Han, Zhengxin Wu, Jianyu Hua, Rui Zhong, Ruidan Zhao, Honggang Ran, Kaiyong Qu, Hongfei Huang, Huamei Tang, Jiyi Huang, Zhongchen Liu, Xuehui Hong, Zhihai Peng, Guohong Zhuang
Publikováno v:
Cell Death Discovery, Vol 7, Iss 1, Pp 1-9 (2021)
Abstract Colorectal cancer (CRC) is a common tumor that harms human health with a high recurrence rate. It has been reported that the expression of microRNA-539 (miR-539) is low in several types of cancer, including CRC. Tumor necrosis factor (TNF)-
Externí odkaz:
https://doaj.org/article/803eab08849d4e059bf3098d12769f83
Autor:
Hui Li, Xiaole Meng, Xuting You, Wenting Zhou, Wanxin Ouyang, Xin Pu, Runan Zhao, Huamei Tang
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
RNA-binding proteins (RBPs) mainly contribute to abnormalities in posttranscriptional gene regulation. The RBP Musashi-2, an evolutionarily conserved protein, has been characterized as an oncoprotein in various tumors. However, the prognostic value a
Externí odkaz:
https://doaj.org/article/a241b30ce8a04cb29c89301a6fac2356
Autor:
Dayang Chen, Mengmeng Wang, Ying Guo, Wei Wu, Xiang Ji, Xiaowen Dou, Huamei Tang, Zengyan Zong, Xiuming Zhang, Dan Xiong
Publikováno v:
Cancer Medicine, Vol 10, Iss 17, Pp 5936-5947 (2021)
Abstract Head and neck squamous cell carcinoma (HNSCC) is a common malignancy worldwide with a poor prognosis. DNA methylation is an epigenetic modification that plays a critical role in the etiology and pathogenesis of HNSCC. The current study aimed
Externí odkaz:
https://doaj.org/article/78dd6a957f694632a5a0ee6c50a4973a
Autor:
Xisheng Liu, Xiaole Meng, Xiao Peng, Qianlan Yao, Fangming Zhu, Zhongyi Ding, Hongze Sun, Xueni Liu, Dan Li, Ying Lu, Huamei Tang, Bin Li, Zhihai Peng
Publikováno v:
Cell Death and Disease, Vol 12, Iss 4, Pp 1-15 (2021)
Abstract Increasing evidence suggests that global downregulation of miRNA expression is a hallmark of human cancer, potentially due to defects in the miRNA processing machinery. In this study, we found that the protein expression of Argonaute 2 (AGO2
Externí odkaz:
https://doaj.org/article/313bc343c7e9480a9027b31545489a83
Autor:
Zhen Li, Lishan Zhang, Qingli Song, Guibin Wang, Wenxiao Yang, Huamei Tang, Ramanathan Srinivasan, Ling Lin, Xiangmin Lin
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
Bacterial antibiotic resistance is a serious global problem; the underlying regulatory mechanisms are largely elusive. The earlier reports states that the vital role of transcriptional regulators (TRs) in bacterial antibiotic resistance. Therefore, w
Externí odkaz:
https://doaj.org/article/0b7319de2d264161ae6ce14ae08709b1
Autor:
Ling Ye, Tao Jiang, Huanzhang Shao, Lin Zhong, Zhaowen Wang, Yuan Liu, Huamei Tang, Bingyu Qin, Xiaoqing Zhang, Junwei Fan
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 7, Iss C, Pp 453-464 (2017)
5-Fluorouracil (5FU)-based adjuvant therapy is the first-line therapy for treating stage II and III colon cancer after surgery. However, its therapeutic efficacy is limited because of chemoresistance, especially in deficient mismatch repair (dMMR) co
Externí odkaz:
https://doaj.org/article/190ddaca89264ecf8332b7b7041dfacb