Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Huaizu, Guo"'
Autor:
Xuekun Wang, Jin Xu, Qingcheng Guo, Zhenhua Li, Jiawei Cao, Rongrong Fu, Mengjiao Xu, Xiang Zhao, Fugui Wang, Xinmeng Zhang, Taimin Dong, Xu Li, Weizhu Qian, Shen Hou, Lusha Ji, Dapeng Zhang, Huaizu Guo
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 12 (2024)
The Chinese hamster ovarian (CHO) cells serve as a common choice in biopharmaceutical production, traditionally cultivated in stirred tank bioreactors (STRs). Nevertheless, the pursuit of improved protein quality and production output for commercial
Externí odkaz:
https://doaj.org/article/f622f91f8c874caca261685bcf9c9c2e
Autor:
Yun Yang, He Wu, Yan Yang, Yan Kang, Runjia He, Bei Zhou, Huaizu Guo, Jing Zhang, Jianqin Li, Chunpo Ge, Tianyun Wang
Publikováno v:
Molecular Therapy: Oncolytics, Vol 31, Iss , Pp 100747- (2023)
CD47 and its receptor signal regulatory protein α (SIRPα) act as a dominant antiphagocytic, “don’t eat me” signal. Recent studies reveal CD24 as a novel target for cancer immunotherapy by macrophages in ovarian cancer and breast cancer. Howev
Externí odkaz:
https://doaj.org/article/2e58db2bf8064133a0ba132a5303ef8b
Autor:
Tao Liu, Jin Xu, Qingcheng Guo, Dapeng Zhang, Jun Li, Weizhu Qian, Huaizu Guo, Xinli Zhou, Sheng Hou
Publikováno v:
Frontiers in Chemistry, Vol 10 (2022)
Succinimide (Asu) is the intermediate for asparagine deamidation in therapeutic proteins, and it can be readily hydrolyzed to form aspartate and iso-aspartate residues. Moreover, Asu plays an important role in the protein degradation pathways, aspara
Externí odkaz:
https://doaj.org/article/5f3ee0b26b2d4cf3afdf3973c00ae3e3
Autor:
Yin Su, Jing Li, Chenguang Wang, Xunmin Zhang, Sheng Hou, Huaizu Guo, Chenhui Deng, Lun Ou, Jinwei Wang
Publikováno v:
Advances in Therapy. 40:1005-1018
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::90e343a478eac301b78e747fdb4859f4
https://doi.org/10.1007/s12325-022-02396-8
https://doi.org/10.1007/s12325-022-02396-8
Autor:
Huahua, Pu, Jingying, Jia, Chunyang, Zhao, Sheng, Hou, Huaizu, Guo, Jing, Li, Weizhu, Qian, Hao, Wang, Chan, Sun, Yang, Zou
Publikováno v:
Clinical Pharmacology in Drug Development. 12:181-189
The test drug, a recombinant humanized monoclonal antibody, is a biosimilar candidate for the reference drug. The purpose of this study was to evaluate the bioequivalence of these two drugs. The study was divided into two parts, a pre-study and a for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b4de38d957c8da5618a8b5fa76855bc
https://doi.org/10.1002/cpdd.1189
https://doi.org/10.1002/cpdd.1189
Autor:
Yajun Guo, Hao Wang, Jinqiu He, Geng Kou, Huaizu Guo, Bohua Li, Weizhu Qian, Sheng Hou, Dapeng Zhang, Suhui Wang, Huafeng Wei
Purpose: CD11c is an antigen receptor predominantly expressed on dendritic cells (DC), to which antigen targeting has been shown to induce robust antigen-specific immune responses. To facilitate targeted delivery of tumor antigens to DCs, we generate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::309b24cf440fa38b67d67be9bc3c075a
https://doi.org/10.1158/1078-0432.c.6517824
https://doi.org/10.1158/1078-0432.c.6517824
Autor:
Yajun Guo, Jian Zhao, Mengchao Wu, Hao Wang, Chang Liu, Wenming Cong, Anmin Liang, Huaizu Guo, Xin Tong, Guobin Wu, Yunchao Ma, Bin Lu
Purpose: To investigate Tip30 promoter methylation status in human hepatocellular carcinoma (HCC) and the correlation with clinicopathologic features and prognosis.Experimental Design: The methylation status of CpG islands in Tip30 promoter was exami
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e9ebaaf047390bb9487594d1e77503a
https://doi.org/10.1158/1078-0432.c.6516930.v1
https://doi.org/10.1158/1078-0432.c.6516930.v1
Autor:
Yajun Guo, Hao Wang, Jinqiu He, Geng Kou, Huaizu Guo, Bohua Li, Weizhu Qian, Sheng Hou, Dapeng Zhang, Suhui Wang, Huafeng Wei
Supplementary Data from Targeted Delivery of Tumor Antigens to Activated Dendritic Cells via CD11c Molecules Induces Potent Antitumor Immunity in Mice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20632032d5753549785f7d08e7a6519a
https://doi.org/10.1158/1078-0432.22440507.v1
https://doi.org/10.1158/1078-0432.22440507.v1
Autor:
Yajun Guo, Jian Zhao, Mengchao Wu, Hao Wang, Chang Liu, Wenming Cong, Anmin Liang, Huaizu Guo, Xin Tong, Guobin Wu, Yunchao Ma, Bin Lu
Supplementary Data from Methylation of Tip30 Promoter Is Associated with Poor Prognosis in Human Hepatocellular Carcinoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29d59246d3d0a7bf1c3d0991e8f1620f
https://doi.org/10.1158/1078-0432.22439469.v1
https://doi.org/10.1158/1078-0432.22439469.v1
Autor:
Yin, Su, Jing, Li, Chenguang, Wang, Xunmin, Zhang, Sheng, Hou, Huaizu, Guo, Chenhui, Deng, Lun, Ou, Jinwei, Wang
Publikováno v:
Advances in therapy.
CMAB008 is a monoclonal antibody developed as a biosimilar to infliximab (RemicadeThe population pharmacokinetic model was developed on the basis of intensive pharmacokinetic data from a phase 1 study in healthy male subjects and combined intensive a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::be110c5fb445bfb40ef7a839edfc58a9
https://pubmed.ncbi.nlm.nih.gov/36607544
https://pubmed.ncbi.nlm.nih.gov/36607544