Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Huaizong, Shen"'
Autor:
Qiong Guo, Shidong Zhao, Rosario Francisco-Velilla, Jiahai Zhang, Azman Embarc-Buh, Salvador Abellan, Mengqi Lv, Peiping Tang, Qingguo Gong, Huaizong Shen, Linfeng Sun, Xuebiao Yao, Jinrong Min, Yunyu Shi, Encarnacion Martínez-Salas, Kaiming Zhang, Chao Xu
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-10 (2022)
Structural biology, complemented by biochemistry experiments and RNA-binding assays show that the Gemin5 C-terminal region adopts a decamer architecture. Gemin5 decamerization is essential for its role in regulating mRNA translation.
Externí odkaz:
https://doaj.org/article/1415af1fefb643b1be8b200fb6c9501e
Autor:
Gaoxingyu, Huang, Dongliang, Liu, Weipeng, Wang, Qiurong, Wu, Jiaofeng, Chen, Xiaojing, Pan, Huaizong, Shen, Nieng, Yan
Publikováno v:
Cell reports. 39(4)
Na
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e04ff747226964e188b5f8fa7038317a
https://pubmed.ncbi.nlm.nih.gov/35476982
https://pubmed.ncbi.nlm.nih.gov/35476982
Publikováno v:
Science Advances
Description
The cryo-EM structure of the human Meckelin reveals a unique protein fold.
Mutations in the Meckelin gene account for most cases of the Meckel-Gruber syndrome, the most severe ciliopathy with a 100% mortality rate. Here, we repo
The cryo-EM structure of the human Meckelin reveals a unique protein fold.
Mutations in the Meckelin gene account for most cases of the Meckel-Gruber syndrome, the most severe ciliopathy with a 100% mortality rate. Here, we repo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afee2417cc05eb0d934f7f8c7bdcf564
https://doi.org/10.1126/sciadv.abj9748
https://doi.org/10.1126/sciadv.abj9748
Publikováno v:
Science. 363:1303-1308
Targeting sodium channels Voltage-gated sodium (Na v ) channels have been implicated in cardiac and neurological disorders. There are many subtypes of these channels, making it challenging to develop specific therapeutics. A core α subunit is suffic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b6ae31fcc50f4d3443a6a482ec095968
https://doi.org/10.1126/science.aaw2493
https://doi.org/10.1126/science.aaw2493
Autor:
Nieng Yan, Huaizong Shen, Xiaojing Pan, Jianlin Lei, Zhangqiang Li, Gaoxingyu Huang, Shuai Gao, Lei Liu, Xiaoshuang Huang
Publikováno v:
Science. 363:1309-1313
Targeting sodium channels Voltage-gated sodium (Na v ) channels have been implicated in cardiac and neurological disorders. There are many subtypes of these channels, making it challenging to develop specific therapeutics. A core α subunit is suffic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7ecd23c3bc9436992dcf94816b61802d
https://doi.org/10.1126/science.aaw2999
https://doi.org/10.1126/science.aaw2999
Publikováno v:
Methods in enzymology. 653
Voltage-gated sodium (Na
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::76f7a20439e86cfbeb719534434e5ba4
https://pubmed.ncbi.nlm.nih.gov/34099168
https://pubmed.ncbi.nlm.nih.gov/34099168
Publikováno v:
Methods in Enzymology ISBN: 9780323853767
Voltage-gated sodium (Nav) channels are responsible for the initiation and propagation of action potentials. Their abnormal functions are associated with numerous diseases, such as epilepsy, cardiac arrhythmia, and pain syndromes. Therefore, these ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::99a698f291777896dc8ef696ec1033ab
https://doi.org/10.1016/bs.mie.2021.03.010
https://doi.org/10.1016/bs.mie.2021.03.010
Autor:
Gaoxingyu Huang, Dongliang Liu, Weipeng Wang, Qiurong Wu, Jiaofeng Chen, Xiaojing Pan, Huaizong Shen, Nieng Yan
Publikováno v:
Cell Reports. 39:110735
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a0aa6addc9fc49cc9460fecbd27b22fe
https://doi.org/10.1016/j.celrep.2022.110735
https://doi.org/10.1016/j.celrep.2022.110735
Autor:
Wei Peng1,2, Huaizong Shen1,2,3, Jianping Wu1,2,3, Wenting Guo4, Xiaojing Pan1,2, Ruiwu Wang4, Chen, S. R. Wayne4 swchen@ucalgary.ca, Nieng Yan1,2,3 nyan@tsinghua.edu.cn
Publikováno v:
Science. 10/21/2016, Vol. 354 Issue 6310, paah5324-1-aah5324-10. 10p. 3 Color Photographs, 3 Graphs.
Publikováno v:
Science (New York, N.Y.). 363(6433)
Voltage-gated sodium channel Na
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::13cd72fcf7ce87be6af9a11700490cf1
https://pubmed.ncbi.nlm.nih.gov/30765606
https://pubmed.ncbi.nlm.nih.gov/30765606