Zobrazeno 1 - 10
of 95
pro vyhledávání: '"Huaizhu Wu"'
Autor:
Hua Mao, Luge Li, Qiying Fan, Aude Angelini, Pradip K. Saha, Cristian Coarfa, Kimal Rajapakshe, Dimuthu Perera, Jizhong Cheng, Huaizhu Wu, Christie M. Ballantyne, Zheng Sun, Liang Xie, Xinchun Pi
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
The vascular endothelium contributes to metabolic regulation, however, the underlying mechanisms are not fully understood. Here the authors show that endothelial low-density lipoprotein receptor-related protein 1 regulates glucose homeostasis via ost
Externí odkaz:
https://doaj.org/article/2bb6c637cb5f4e2eb55a2f359b4beb74
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 14, p 11782 (2023)
When stimulated by proinflammatory mediators, endothelial cells release ultra-large von Willebrand factor (ULVWF) multimers that are hyperactive in activating and aggregating platelets. These ULVWF multimers can accumulate in the circulation and on t
Externí odkaz:
https://doaj.org/article/80da20128243488d91d38e4ded4f5948
Autor:
Neeti Agarwal, Claudia E. Ramirez Bustamante, Huaizhu Wu, Reina Armamento‐Villareal, Jordan E. Lake, Ashok Balasubramanyam, Sean M. Hartig
Publikováno v:
Physiological Reports, Vol 10, Iss 9, Pp n/a-n/a (2022)
Abstract Plasma biomarkers that reflect energy balance disorders in people living with HIV (PLWH) remain limited. Growth differentiation factor 15 (GDF15) abundance in plasma of mice and humans induces negative energy balance but also becomes highly
Externí odkaz:
https://doaj.org/article/d305955a3d7c4aa78b5e34a1362655a4
Autor:
Hua Mao, Luge Li, Qiying Fan, Aude Angelini, Pradip K. Saha, Huaizhu Wu, Christie M. Ballantyne, Sean M. Hartig, Liang Xie, Xinchun Pi
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
Type 2 diabetes is associated with chronic inflammation and is characterized by insulin resistance. Here, the authors identify a crucial role for endothelial BMPER function in glucose homeostasis, and BMPER overexpression was shown to alleviate insul
Externí odkaz:
https://doaj.org/article/955957e083474c468a00c6e9258ec4a1
Autor:
Xueying Peng, Zeqin Lian, Xiao-Yuan Dai Perrard, Yunjie Xiao, Jing Ni, Veronica O’Brien, Henry Dong, Henry J. Pownall, Christie M. Ballantyne, Huaizhu Wu
Publikováno v:
Cells, Vol 11, Iss 11, p 1795 (2022)
Background: Hypertriglyceridemia (HTG) increases the risk for atherosclerotic cardiovascular disease, but underlying mechanisms are incompletely understood. Circulating monocytes play an important role in atherogenesis by infiltrating arterial walls,
Externí odkaz:
https://doaj.org/article/bc08e2051f9a4c01b99a11cc5049aa32
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Externí odkaz:
https://doaj.org/article/feb0635bca25471cadfcaa73836a5ae8
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Similar to obesity, aging is associated with visceral adiposity and insulin resistance. Inflammation in adipose tissue, mainly evidenced by increased accumulation and proinflammatory polarization of T cells and macrophages, has been well-documented i
Externí odkaz:
https://doaj.org/article/0e31b95dc141447fbd94c3ea74183cd2
Autor:
Qun Wang, Huaizhu Wu
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Adipose tissue performs immunoregulatory functions in addition to fat storage. Various T cells in different fat depots either help maintain metabolic homeostasis under healthy conditions or contribute to metabolic disorders in pathological conditions
Externí odkaz:
https://doaj.org/article/dd9aeb4d63ef42b0a3540c114b898e31
Autor:
Lu Xu, Fan Ping, Jinhua Yin, Xinhua Xiao, Hongding Xiang, Christie M Ballantyne, Huaizhu Wu, Ming Li
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e81615 (2013)
OBJECTIVE: Recent studies suggested that secreted protein acidic and rich in cysteine (SPARC), a novel adipokine, is a key player in the pathology of obesity and type 2 diabetes. We aimed to determine whether concentrations of SPARC were altered in p
Externí odkaz:
https://doaj.org/article/3d7d9e73a83a4e2283c05d9e85812939
Autor:
Zeqin Lian, Xiao-Yuan Dai Perrard, Antu Kalathookunnel Antony, Xueying Peng, Lu Xu, Jing Ni, Bingqian Zhang, Veronica O’Brien, Anum Saeed, Xiaoming Jia, Aliza Hussain, Bing Yu, Scott I. Simon, Frank M. Sacks, Ron C. Hoogeveen, Christie M. Ballantyne, Huaizhu Wu
Publikováno v:
JACC: Basic to Translational Science. 8:460-475